دورية أكاديمية
Predictive Low Glucose Suspend Algorithm in Real Life: A Five-Year Follow-Up Retrospective Analysis.
العنوان: | Predictive Low Glucose Suspend Algorithm in Real Life: A Five-Year Follow-Up Retrospective Analysis. |
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المؤلفون: | Tubili C; Diabetes Unit, 'S. Camillo-Forlanini' Hospital, Rome, Italy., Pollakova D; Diabetes Unit, 'S. Camillo-Forlanini' Hospital, Rome, Italy., Nardone MR; Diabetes Unit, 'S. Camillo-Forlanini' Hospital, Rome, Italy., Di Folco U; Diabetes Unit, 'S. Camillo-Forlanini' Hospital, Rome, Italy. |
المصدر: | Journal of diabetes science and technology [J Diabetes Sci Technol] 2021 Nov; Vol. 15 (6), pp. 1303-1307. Date of Electronic Publication: 2020 Aug 29. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Sage Country of Publication: United States NLM ID: 101306166 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-2968 (Electronic) Linking ISSN: 19322968 NLM ISO Abbreviation: J Diabetes Sci Technol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2014- : Thousand Oaks, CA : Sage Original Publication: Foster City, CA : Diabetes Technology Society |
مواضيع طبية MeSH: | Blood Glucose Self-Monitoring* , Diabetes Mellitus, Type 1*/drug therapy, Adult ; Algorithms ; Blood Glucose ; Follow-Up Studies ; Glycated Hemoglobin ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Insulin Infusion Systems ; Quality of Life ; Retrospective Studies |
مستخلص: | Aim: Sensor-augmented pumps with predictive low glucose suspend function (PLGS-SAP) help patients avoid hypoglycemia and improve quality of life: in this retrospective study, we investigated long-term effects of PLGS-SAP on metabolic outcomes, acute and chronic diabetic complications, in particular cardiovascular events. Materials and Methods: One hundred thirty-nine adults with type 1 diabetes (T1D) treated for more than 10 years with continuous subcutaneous insulin infusion (CSII) were followed for 5 years; 71 (Group 1) started to use PLGS-SAP, and 68 (Group 2) maintained on their non-PLGM insulin pump. Glucose control measures (hemoglobin A1c [HbA1c], acute diabetic complications), clinical outcomes (body mass index [BMI], arterial hypertension, dyslipidemia), chronic diabetes-related complications, and device utilization (continuous glucose monitoring utilization, use of temporary basal rates or special boluses, carbohydrate counting usage) were assessed. Results: The reduction of HbA1c was significant in Group 1 (from 7.5% ± 1.1% to 7.0% ± 1.0%, P = .02), while in Group 2 it did not reach statistical significance (from 7.5% ± 1.1% to 7.4% ± 0.9%, P = .853). BMI increased significantly in Group 2 (from 25.3 ± 2.8 to 25.7 ± 3.4, P < .001), but not in Group 1 (from 25.2 ± 3.5 to 25.2 ± 2.8, P = .887). There were no statistically significant differences in occurrence of acute diabetes complications, other clinical outcomes, prevalence of diabetes-related complications, or device utilization between the groups. Conclusions: In our five-year follow-up experience with T1D CSII users, PLGS-SAP has resulted efficient in improving metabolic control and maintaining the body weight. |
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فهرسة مساهمة: | Keywords: body mass index; continuous subcutaneous insulin infusion; predictive low glucose suspend; sensor-augmented pump; type 1 diabetes mellitus |
المشرفين على المادة: | 0 (Blood Glucose) 0 (Glycated Hemoglobin A) 0 (Hypoglycemic Agents) 0 (Insulin) |
تواريخ الأحداث: | Date Created: 20200901 Date Completed: 20211129 Latest Revision: 20221207 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC8655276 |
DOI: | 10.1177/1932296820952107 |
PMID: | 32865016 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1932-2968 |
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DOI: | 10.1177/1932296820952107 |