دورية أكاديمية
The structure of myeloid cell-specific TNF inhibitors affects their biological properties.
| العنوان: | The structure of myeloid cell-specific TNF inhibitors affects their biological properties. |
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| المؤلفون: | Vasilenko EA; Lobachevsky State University, Nizhny Novgorod, Russia., Gorshkova EN; Lobachevsky State University, Nizhny Novgorod, Russia., Astrakhantseva IV; Lobachevsky State University, Nizhny Novgorod, Russia.; Sirius University of Science and Technology, Sochi, Russia., Drutskaya MS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Tillib SV; Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia., Nedospasov SA; Sirius University of Science and Technology, Sochi, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Lomonosov Moscow State University, Moscow, Russia., Mokhonov VV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Blokhina Scientific Research Institute of Epidemiology and Microbiology of Nizhny Novgorod, Nizhny Novgorod, Russia. |
| المصدر: | FEBS letters [FEBS Lett] 2020 Nov; Vol. 594 (21), pp. 3542-3550. Date of Electronic Publication: 2020 Sep 04. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2016- : West Sussex : John Wiley & Sons Ltd. Original Publication: Amsterdam, North-Holland on behalf of the Federation of European Biochemical Societies. |
| مواضيع طبية MeSH: | Myeloid Cells/*drug effects , Tumor Necrosis Factor Inhibitors/*pharmacology, Animals ; Antibodies, Bispecific/pharmacology ; Chemical and Drug Induced Liver Injury ; Galactosamine ; Humans ; Lipopolysaccharides ; Macrophages/drug effects ; Mice ; Survival Rate ; Tumor Necrosis Factor-alpha/pharmacology |
| مستخلص: | Spatial organization and conformational changes of antibodies may significantly affect their biological functions. We assessed the effect of mutual organization of the two V (© 2020 Federation of European Biochemical Societies.) |
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| فهرسة مساهمة: | Keywords: VHH; anti-TNF therapy; bispecific antibodies; linkers |
| المشرفين على المادة: | 0 (Antibodies, Bispecific) 0 (Lipopolysaccharides) 0 (Tumor Necrosis Factor Inhibitors) 0 (Tumor Necrosis Factor-alpha) 7535-00-4 (Galactosamine) |
| تواريخ الأحداث: | Date Created: 20200901 Date Completed: 20210520 Latest Revision: 20210520 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1002/1873-3468.13913 |
| PMID: | 32865225 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3468 |
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| DOI: | 10.1002/1873-3468.13913 |