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أعرض في EDS

Bridging "Big Data" and Mechanistic Insight To Enable Precision Medicine.

التفاصيل البيبلوغرافية
العنوان: Bridging "Big Data" and Mechanistic Insight To Enable Precision Medicine.
المؤلفون: Douglass EF Jr; Department of Systems Biology, Columbia University, 1130 St Nicholas Ave, New York, NY, 10032, USA.
المصدر: Chembiochem : a European journal of chemical biology [Chembiochem] 2020 Nov 02; Vol. 21 (21), pp. 3047-3050. Date of Electronic Publication: 2020 Aug 31.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Weinheim, Germany : Wiley-VCH Verlag, c2000-
مواضيع طبية MeSH: Big Data* , Precision Medicine*, Databases, Factual ; Humans
مستخلص: Realizing the promise of precision medicine will require breaking down communication barriers between genomic, screening and literature "big data." We discuss the opportunities and challenges of reconciling data science approaches with the scientific method and the critical role of chemical biologists as a bridge between data and mechanism. Finally we propose next steps on the road to precision medicine and give examples of new tools designed to catalyze these steps.
(© 2020 Wiley-VCH GmbH.)
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فهرسة مساهمة: Keywords: big data; chemical biology; data science; mechanisms; precision medicine
تواريخ الأحداث: Date Created: 20200901 Date Completed: 20210706 Latest Revision: 20210706
رمز التحديث: 20231215
DOI: 10.1002/cbic.202000494
PMID: 32865878
قاعدة البيانات: MEDLINE
الوصف
تدمد:1439-7633
DOI:10.1002/cbic.202000494