دورية أكاديمية
Bridging "Big Data" and Mechanistic Insight To Enable Precision Medicine.
العنوان: | Bridging "Big Data" and Mechanistic Insight To Enable Precision Medicine. |
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المؤلفون: | Douglass EF Jr; Department of Systems Biology, Columbia University, 1130 St Nicholas Ave, New York, NY, 10032, USA. |
المصدر: | Chembiochem : a European journal of chemical biology [Chembiochem] 2020 Nov 02; Vol. 21 (21), pp. 3047-3050. Date of Electronic Publication: 2020 Aug 31. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Weinheim, Germany : Wiley-VCH Verlag, c2000- |
مواضيع طبية MeSH: | Big Data* , Precision Medicine*, Databases, Factual ; Humans |
مستخلص: | Realizing the promise of precision medicine will require breaking down communication barriers between genomic, screening and literature "big data." We discuss the opportunities and challenges of reconciling data science approaches with the scientific method and the critical role of chemical biologists as a bridge between data and mechanism. Finally we propose next steps on the road to precision medicine and give examples of new tools designed to catalyze these steps. (© 2020 Wiley-VCH GmbH.) |
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فهرسة مساهمة: | Keywords: big data; chemical biology; data science; mechanisms; precision medicine |
تواريخ الأحداث: | Date Created: 20200901 Date Completed: 20210706 Latest Revision: 20210706 |
رمز التحديث: | 20231215 |
DOI: | 10.1002/cbic.202000494 |
PMID: | 32865878 |
قاعدة البيانات: | MEDLINE |
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