دورية أكاديمية
The Midwest ST-Elevation Myocardial Infarction Consortium: Design and Rationale.
| العنوان: | The Midwest ST-Elevation Myocardial Infarction Consortium: Design and Rationale. |
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| المؤلفون: | Yildiz M; The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, Cincinnati, OH, United States of America., Sharkey S; Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN, United States of America., Aguirre FV; Prairie Heart Institute at St John's Hospital, Springfield, IL, United States of America., Tannenbaum M; Iowa Heart Center, Des Moines, IA, United States of America., Garberich R; Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN, United States of America., Smith TD; The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, Cincinnati, OH, United States of America., Shivapour D; Iowa Heart Center, Des Moines, IA, United States of America., Schmidt CW; Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN, United States of America., Pacheco-Coronado R; Prairie Heart Institute at St John's Hospital, Springfield, IL, United States of America., Rohm HS; The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, Cincinnati, OH, United States of America., Chambers J; Prairie Heart Institute at St John's Hospital, Springfield, IL, United States of America., Coulson T; Iowa Heart Center, Des Moines, IA, United States of America., Garcia S; Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN, United States of America., Henry TD; The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, Cincinnati, OH, United States of America. Electronic address: tim.henry@thechristhospital.com. |
| المصدر: | Cardiovascular revascularization medicine : including molecular interventions [Cardiovasc Revasc Med] 2021 Feb; Vol. 23, pp. 86-90. Date of Electronic Publication: 2020 Aug 13. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 101238551 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0938 (Electronic) Linking ISSN: 18780938 NLM ISO Abbreviation: Cardiovasc Revasc Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, NY : Elsevier, c2005- |
| مواضيع طبية MeSH: | Percutaneous Coronary Intervention*/adverse effects , ST Elevation Myocardial Infarction*/diagnostic imaging , ST Elevation Myocardial Infarction*/therapy, Female ; Humans ; Infant, Newborn ; Registries ; Risk Factors ; Shock, Cardiogenic ; Stroke Volume ; Treatment Outcome ; Ventricular Function, Left |
| مستخلص: | Background: Over the past 20 years, the development of regional ST-elevation myocardial infarction (STEMI) care systems has led to remarkable progress in achieving timely coronary reperfusion with attendant improvement in clinical outcomes, including survival. Despite this progress, contemporary STEMI care does not consistently meet the national guideline-recommended goals, which offers an opportunity for further improvement in STEMI outcomes. The lack of single, comprehensive, national STEMI registry complicates our ability to improve STEMI outcomes in particular for high-risk STEMI subsets such as cardiac arrest (CA) and/or cardiogenic shock (CS). Objectives: To address this need, the Midwest STEMI Consortium (MSC) was created as a collaboration of 4 large, regional STEMI care systems to provide a comprehensive, multicenter, and prospective STEMI registry without any exclusionary criteria. Methods: The MSC is a collaboration of 4 large, regional STEMI care systems: Iowa Heart Center in Des Moines, IA; Minneapolis Heart Institute Foundation in Minneapolis, MN; Prairie Heart Institute in Springfield, IL; and The Christ Hospital in Cincinnati, OH. Each has similar standardized STEMI protocol and together include 6 percutaneous coronary intervention (PCI)-capable hospitals and over 100 non-PCI-capable hospitals. Each center had a prospective database that was transferred to a data coordinating center to create the multicenter database. The comprehensive database includes traditional risk factors, cardiovascular history, medications, time to treatment data, detailed angiographic characteristics, and short- and long-term clinical outcomes up to 5-year for myocardial infarction, stroke, and cardiovascular and all-cause mortality. Ten-year mortality rates were assessed by using national death index. Results: Currently, the comprehensive database (03/2003-01/2020) includes 14,911 consecutive STEMI patients with mean age of 62.3 ± 13.6 years, female gender (29%), and left anterior descending artery as the culprit vessel (34%). High risk features included: Age >75 years (19%), left ventricular ejection fraction <35% (15%), CA (10%), and CS (8%). Conclusion: This collaboration of 4 large, regional STEMI care systems with broad entry criteria including high-risk STEMI subsets such as CA and/or CS provides a unique platform to conduct clinical research studies to optimize STEMI care. Competing Interests: Declaration of competing interest None. (Copyright © 2020. Published by Elsevier Inc.) |
| فهرسة مساهمة: | Keywords: Angioplasty; Cardiac arrest; Cardiogenic shock; Myocardial infarction; Registry |
| تواريخ الأحداث: | Date Created: 20200905 Date Completed: 20210818 Latest Revision: 20210818 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC7425714 |
| DOI: | 10.1016/j.carrev.2020.08.019 |
| PMID: | 32883587 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1878-0938 |
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| DOI: | 10.1016/j.carrev.2020.08.019 |