دورية أكاديمية

Risk factors for pregnancy-associated venous thromboembolism in Singapore.

التفاصيل البيبلوغرافية
العنوان: Risk factors for pregnancy-associated venous thromboembolism in Singapore.
المؤلفون: Jaya-Bodestyne SL; Duke-NUS Medical School, Singapore, Singapore., Lee LH; Department of Haematology, Singapore General Hospital, Singapore, Singapore., Tan LK; Department of Obstetrics and Gynaecology, Singapore General Hospital, Singapore, Singapore., Tan KH; Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore, Singapore., Østbye T; Duke-NUS Medical School, Singapore, Singapore., Malhotra R; Duke-NUS Medical School, Singapore, Singapore., Allen J; Duke-NUS Medical School, Singapore, Singapore., Tan SSX; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan MSY; Department of Haematology, Singapore General Hospital, Singapore, Singapore., Ng LCK; Department of Haematology, Singapore General Hospital, Singapore, Singapore., Yong Y; Department of Epidemiology, Singapore General Hospital, Singapore, Singapore., Tan TC; Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore, Singapore.
المصدر: Journal of perinatal medicine [J Perinat Med] 2020 Sep 05; Vol. 49 (2), pp. 153-158. Date of Electronic Publication: 2020 Sep 05 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Walter De Gruyter Country of Publication: Germany NLM ID: 0361031 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1619-3997 (Electronic) Linking ISSN: 03005577 NLM ISO Abbreviation: J Perinat Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Berlin : Walter De Gruyter
Original Publication: Berlin, New York, Walter de Gruyter.
مواضيع طبية MeSH: Pregnancy Complications, Cardiovascular/*epidemiology , Venous Thromboembolism/*epidemiology, Adolescent ; Adult ; Case-Control Studies ; Female ; Humans ; Middle Aged ; Pregnancy ; Risk Factors ; Singapore/epidemiology ; Young Adult
مستخلص: Objectives: Pregnancy-associated venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), is associated with increased risk of maternal mortality and morbidity. This study aimed to assess potential risk factors for pregnancy-associated VTE.
Methods: In this case-control study, women with pregnancy-associated VTE were identified via International Classification of Diseases codes and included if they had been objectively diagnosed with VTE during pregnancy or within six weeks postpartum, from 2004 to 2016, at KK Women's and Children's Hospital or Singapore General Hospital in Singapore. Controls, i.e. pregnant women without VTE, were selected from a prospective longitudinal study. The odds ratio (OR) for VTE was computed for a range of maternal and obstetric factors.
Results and Conclusions: From 2004 to 2016, 89 cases of pregnancy-associated VTE and 926 controls were identifed and analysed using logistic regression. The most significant risk factors for pregnancy-associated VTE were smoking (OR 5.44, p=0.0002) and preterm delivery (OR 5.06, p=0.023). Malay race, multiparity, non-O blood group and caesarean section, were also identified to be of higher risk. These risk factors should be useful in the development of thromboprophylaxis strategies for pregnancy and the postpartum period, especially in Singapore.
(© 2020 Sandra Lynn Jaya-Bodestyne et al., published by De Gruyter, Berlin/Boston.)
References: Heit, JA, Kobbervig, CE, James, AH, Petterson, TM, Bailey, KR, Melton, LJ. Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study. Ann Intern Med 2005;143:697–706. https://doi.org/10.7326/0003-4819-143-10-200511150-00006.
Sultan, AA, West, J, Tata, LJ, Fleming, KM, Nelson-Piercy, C, Grainge, MJ. Risk of first venous thromboembolism in and around pregnancy: a population-based cohort study. Br J Haematol 2012;156:366–73. https://doi.org/10.1111/j.1365-2141.2011.08956.x.
Greer, IA. Thrombosis in pregnancy: maternal and fetal issues. Lancet 1999;353:1258–65. https://doi.org/10.1016/s0140-6736(98)10265-9.
Meng, K, Hu, X, Peng, X, Zhang, Z. Incidence of venous thromboembolism during pregnancy and the puerperium: a systematic review and meta-analysis. J Matern Neonatal Med 2015;28:245–53. https://doi.org/10.3109/14767058.2014.913130.
Kourlaba, G, Relakis, J, Kontodimas, S, Holm, MV, Maniadakis, N. A systematic review and meta-analysis of the epidemiology and burden of venous thromboembolism among pregnant women. Int J Gynecol Obstet 2016;132:4–10. https://doi.org/10.1016/j.ijgo.2015.06.054.
Say, L, Chou, D, Gemmill, A, Tuncalp, O, Moller, A, Daniels, J, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Heal 2014;2:323–33. https://doi.org/10.1016/s2214-109x(14)70227-x.
Lau, G. Are maternal deaths on the ascent in Singapore? A review of maternal mortality as reflected by coronial casework from 1990 to 1999. Ann Acad Med Singapore 2002;31:261–75.
Wik, HS, Jacobsen, AF, Sandvik, L, Sandset, PM. Prevalence and predictors for post-thrombotic syndrome 3–16 years after pregnancy-related venous thrombosis: a population-based, cross-sectional, case-control study. J Thromb Haemostasis 2012;10:840–7. https://doi.org/10.1111/j.1538-7836.2012.04690.x.
Wik, HS, Enden, TR, Jacobsen, AF, Sandset, PM. Long-term quality of life after pregnancy-related deep vein thrombosis and the influence of socioeconomic factors and comorbidity. J Thromb Haemostasis 2011;9:1931–6. https://doi.org/10.1111/j.1538-7836.2011.04468.x.
RCOG. Reducing the risk of venous thromboembolism during pregnancy and the puerperium: Green-Top Guideline No. 37a; 2015.
Liew, NC, Alemany, GV, Angchaisuksiri, P, Bang, SM, Choi, G, De Silva, DA, et al. Asian venous thromboembolism guidelines: updated recommendations for the prevention of venous thromboembolism. Int Angiol 2017;36:1–20. https://doi.org/10.23736/s0392-9590.16.03765-2.
Won, HS, Kim, DY, Yang, MS, Lee, SJ, Shin, HH, Parl, JB. Pregnancy-induced hypertension, but not gestational diabetes mellitus, is a risk factor for venous thromboembolism in pregnancy. Korean Circ J 2011;41:23–7. https://doi.org/10.4070/kcj.2011.41.1.23.
Gader, AA, Haggaz, AED, Adam, I. Epidemiology of deep venous thrombosis during pregnancy and puerperium. Vasc Health Risk Manag 2009;5:2007–10. https://doi.org/10.2147/VHRM.S4196.
Kevane, B, Donnelly, J, D’Alton, M, Cooley, S, Preston, RJS, Ainle, FN. Risk factors for pregnancy-associated venous thromboembolism: a review. J Perinat Med 2014;42:417–25. https://doi.org/10.1515/jpm-2013-0207.
Larsen, TB, Johnsen, SP, Gislum, M, Møller, CAI, Larsen, H, Søresnsen, HT. ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A population-based, nested case-control study. J Thromb Haemostasis 2005;3:300–4. https://doi.org/10.1111/j.1538-7836.2005.01195.x.
Blondon, M, Quon, BS, Harrington, LB, Bounameaux, H, Smith, NL. Association between newborn birth weight and the risk of postpartum maternal venous thromboembolism a population-based case-control study. Circulation 2015;131:1471–6. https://doi.org/10.1161/circulationaha.114.012749.
Lim, WY, Saw, SM, Tan, KH, Yeo, GSH, Kwek, KYC. A cohort evaluation on arterial stiffness and hypertensive disorders in pregnancy. BMC Pregnancy Childbirth 2012;12:160. https://doi.org/10.1186/1471-2393-12-160.
Rasmussen, KM, Catalano, PM, Yaktine, AL. New guidelines for weight gain during pregnancy: what obstetrician/gynecologists should know. Curr Opin Obstet Gynecol 2009;21:521–6. https://doi.org/10.1097/gco.0b013e328332d24e.
Molina, JAD, Gabriel, ZJ, Heng, BH. Venous thromboembolism at the National Healthcare Group, Singapore. Ann Acad Med Singapore 2009;38:470–7.
White, RH, Keenan, CR. Effects of race and ethnicity on the incidence of venous thromboembolism. Thromb Res 2009;123:S11–7. https://doi.org/10.1016/s0049-3848(09)70136-7.
Robert, A, Aillaud, MF, Eschwège, V, Randrianjohany, A, Scarabin, Y, Juhan-Vague, I. ABO blood group and risk of venous thrombosis in heterozygous carriers of factor V Leiden. Thromb Haemostasis 2000;83:630–1. https://doi.org/10.1055/s-0037-1613876.
Heit, JA, Leibson, CL, Ashrani, AA, Petterson, TM, Bailey, KR, Melton, LJ. Is diabetes mellitus an independent risk factor for venous thromboembolism? A population-based case-control study. Arterioscler Thromb Vasc Biol 2009;29:1399–405. https://doi.org/10.1161/atvbaha.109.189290.
Bonnar, J, McNicol, GP, Douglas, AS. Coagulation and fibrinolytic mechanisms during and after normal childbirth. Br Med J 1970;2:200–3. https://doi.org/10.1136/bmj.2.5703.200.
Boehlen, F, Epiney, M, Boulvain, M, Reber, G, Antonelli, E, Morales, M, et al. D-dimer levels during the pregnancy and the postpartum. Rev Med Suisse 2005;1:296–8. https://doi.org/10.1111/j.1538-7836.2004.01108.x.
Kjellberg, U, Andersson, NE, Rosén, S, Tengborn, L, Hellgren, M. APC resistance and other haemostatic variables during pregnancy and puerperium. Thromb Haemostasis 1999;81:527–31. https://doi.org/10.1055/s-0037-1614518.
فهرسة مساهمة: Keywords: postpartum; pregnancy; risk factors; venous thromboembolism
تواريخ الأحداث: Date Created: 20200905 Date Completed: 20211028 Latest Revision: 20211028
رمز التحديث: 20240628
DOI: 10.1515/jpm-2020-0298
PMID: 32889795
قاعدة البيانات: MEDLINE
الوصف
تدمد:1619-3997
DOI:10.1515/jpm-2020-0298