دورية أكاديمية
European research networks to facilitate drug research in children.
| العنوان: | European research networks to facilitate drug research in children. |
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| المؤلفون: | Turner MA; Institute of Lifecourse and Medical Sciences, University of Liverpool, Liverpool Health Partners, Liverpool, UK., Cheng K; Child Health Innovation Leadership Department (CHILD), Johnson and Johnson, High Wycombe, UK., de Wildt S; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Hildebrand H; Pediatric Development, Research & Development, Pharmaceuticals, Bayer AG, Berlin, Germany., Attar S; Institute of Lifecourse and Medical Sciences, University of Liverpool, Liverpool Health Partners, Liverpool, UK., Rossi P; Academic Department of Pediatrics (DPUO), Unit of Perinatal infection and congenital infectious diseases, Bambino Gesu Children's Hospital-University of Rome Tor Vergata, Rome, Italy., Bonifazi D; Consorzio per Valutazioni Biologiche e Farmacologiche, Bari, Italy., Ceci A; Fondazione per la Ricerca Farmacologica Gianni Benzi Onlus, Bari, Italy., Claverol J; Institut de Recerca Sant Joan de Deu, Sant Joan de Deu Research Foundation, Barcelona, Spain., Nafria B; Institut de Recerca Sant Joan de Deu, Sant Joan de Deu Research Foundation, Barcelona, Spain., Giaquinto C; Division of Pediatric Infectious Diseases, Department of Woman's and Child's Health, University of Padua, Padua, Italy. |
| المصدر: | British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Oct; Vol. 88 (10), pp. 4258-4266. Date of Electronic Publication: 2020 Sep 20. |
| نوع المنشور: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Wiley-Blackwell Original Publication: London, Macmillan Journals Ltd. |
| مواضيع طبية MeSH: | Pharmaceutical Research*, Child ; Europe ; Humans ; Translational Research, Biomedical |
| مستخلص: | Paediatric drug development faces several barriers. These include fragmentation of stakeholders and inconsistent processes during the conduct of research. This review summarises recent efforts to overcome these barriers in Europe. Two exemplar initiatives are described. The European Paediatric Translational Research Infrastructure facilitates preclinical research and other work that underpins clinical trials. conect4children facilitates the design and implementation of clinical trials. Both these initiatives listen to the voices of children and their advocates. Coordination of research needs specific effort that supplements work on science, resources and the policy context. (© 2020 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.) |
| References: | Eur J Pediatr. 2015 Apr;174(4):481-91. (PMID: 25241827) Arch Dis Child. 2019 Apr;104(4):385-388. (PMID: 30902887) Acta Paediatr. 2020 Mar;109(3):607-612. (PMID: 31532836) Br J Clin Pharmacol. 2022 Oct;88(10):4258-4266. (PMID: 32893382) Arch Dis Child. 2019 Jun;104(6):601-604. (PMID: 31101643) Birth Defects Res B Dev Reprod Toxicol. 2011 Aug;92(4):254-60. (PMID: 21638754) Arch Dis Child. 2019 May;104(5):494-500. (PMID: 31000534) Rand Health Q. 2017 Jan 13;6(2):13. (PMID: 28845351) Bull World Health Organ. 2003;81(11):815-20. (PMID: 14758408) Arch Dis Child. 2019 Sep;104(9):900-905. (PMID: 31201156) Paediatr Drugs. 2017 Dec;19(6):505-513. (PMID: 28900869) Eur J Cancer. 2015 Jan;51(2):218-24. (PMID: 25434924) J Clin Pharmacol. 2018 Oct;58 Suppl 10:S10-S25. (PMID: 30248190) Pediatr Res. 2016 Apr;79(4):662-9. (PMID: 26650344) Eur J Cancer. 2020 Sep;136:116-129. (PMID: 32688206) Paediatr Drugs. 2016 Aug;18(4):251-60. (PMID: 27142473) |
| فهرسة مساهمة: | Keywords: drug development; paediatric; research infrastructure |
| تواريخ الأحداث: | Date Created: 20200907 Date Completed: 20220913 Latest Revision: 20221015 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9546307 |
| DOI: | 10.1111/bcp.14545 |
| PMID: | 32893382 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1365-2125 |
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| DOI: | 10.1111/bcp.14545 |