دورية أكاديمية
(-)-Tetrahydroberberrubine∙acetate accelerates antioxidant potential and inhibits food associated Bacillus cereus in rice.
| العنوان: | (-)-Tetrahydroberberrubine∙acetate accelerates antioxidant potential and inhibits food associated Bacillus cereus in rice. |
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| المؤلفون: | Bajpai VK; Department of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Seoul 04620, Republic of Korea., Park I; College of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea; Natural Product Informatics Research Center, Korea Institute of Science and Technology (KIST), Gangneung Institute, Gangneung 25451, Republic of Korea., Khan I; Department of Biological Engineering, Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Republic of Korea; The Hormel Institute, University of Minnesota, Austin, MN, 55912, USA., Alshammari FH; Department of Food Science and Biotechnology, Graduate School, Kyungpook National University, Daegu 41566, Republic of Korea., Kumar P; Department of Forestry, North Eastern Regional Institute of Science and Technology, Nirjuli 791109, Arunachal Pradesh, India., Chen L; College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China. Electronic address: chenlei841114@hotmail.com., Na M; College of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea. Electronic address: mkna@cnu.ac.kr., Huh YS; Department of Biological Engineering, Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Republic of Korea. Electronic address: yunsuk.huh@inha.ac.kr., Han YK; Department of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Seoul 04620, Republic of Korea. Electronic address: ykenergy@dongguk.edu., Shukla S; Department of Food Science and Technology, National Institute of Food Technology Entrepreneurship and Management (NIFTEM), Sonipat, Haryana 131028, India. Electronic address: shruti.shukla15@yahoo.com. |
| المصدر: | Food chemistry [Food Chem] 2021 Mar 01; Vol. 339, pp. 127902. Date of Electronic Publication: 2020 Aug 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Barking : Elsevier Applied Science Publishers Original Publication: Barking, Eng., Applied Science Publishers. |
| مواضيع طبية MeSH: | Anti-Infective Agents/*pharmacology , Antioxidants/*metabolism , Berberine/*analogs & derivatives , Biofilms/*drug effects , Oryza/*microbiology, Alkaloids/chemistry ; Animals ; Anti-Infective Agents/chemistry ; Antioxidants/pharmacology ; Bacillus cereus/physiology ; Bacillus cereus/radiation effects ; Berberine/chemistry ; Berberine/pharmacology ; Biofilms/radiation effects ; Cell Survival/drug effects ; Food Microbiology ; Mice ; NIH 3T3 Cells ; Reactive Oxygen Species/metabolism ; Superoxide Dismutase-1/metabolism ; Ultraviolet Rays |
| مستخلص: | A protoberberine alkaloid, (-)-tetrahydroberberrubine∙acetate (THBA) was assessed for its antioxidant potential and ability to inhibit the growth of a food hazard bacterium Bacillus cereus in vitro and in situ. THBA displayed significant and dose-dependent cellular antioxidant potential against hydrogen peroxide-induced oxidative stress in NIH 3T3 fibroblast cells and decreased the ROS levels as well as increased the expression levels of SOD1 and SOD2 enzymes. The inhibitory spectrum of THBA confirmed its mechanistic role in the disruption of the membrane integrity of B. cereus as evidenced by the results of time-inactivation, cell membrane integrity, NPN membrane uptake, membrane potential, and electron microscopy analyses. Moreover, THBA inhibited biofilm formation by B. cereus and disrupted pre-established biofilms on a glass surface. Furthermore, THBA was also able to inhibit B. cereus in raw rice with a significant amount of reduction in CFU counts, suggesting its potential role as a natural antioxidant and antimicrobial agent. (Copyright © 2020 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: (−)-Tetrahydroberberrubine∙acetate; Antioxidant, Bacillus cereus; Biofilm inhibition; Food rice model; Scanning electron microscopy (SEM); Transmission electron microscopy (TEM) |
| المشرفين على المادة: | 0 (Alkaloids) 0 (Anti-Infective Agents) 0 (Antioxidants) 0 (Reactive Oxygen Species) 0I8Y3P32UF (Berberine) EC 1.15.1.1 (Superoxide Dismutase-1) QBN8KZ3C3X (tetrahydroberberrubine) |
| تواريخ الأحداث: | Date Created: 20200913 Date Completed: 20201214 Latest Revision: 20201214 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.foodchem.2020.127902 |
| PMID: | 32920304 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-7072 |
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| DOI: | 10.1016/j.foodchem.2020.127902 |