دورية أكاديمية
أعرض في EDS

The Effects of Antioxidant Vitamins on Proinflammatory Cytokines and Some Biochemical Parameters of Power Plant Workers: A Double-Blind Randomized Controlled Clinical Trial.

التفاصيل البيبلوغرافية
العنوان: The Effects of Antioxidant Vitamins on Proinflammatory Cytokines and Some Biochemical Parameters of Power Plant Workers: A Double-Blind Randomized Controlled Clinical Trial.
المؤلفون: Bagheri Hosseinabadi M; School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran., Khanjani N; Environmental Health Engineering Research Center, Kerman University of Medical Sciences, Kerman, Iran., Norouzi P; School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran., Faghihi-Zarandi A; Department of Occupational Health Engineering, Modelling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran., Darban-Sarokhalil D; Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., Khoramrooz SS; Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran., Mirbadie SR; School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran., Mirzaii M; School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
المصدر: Bioelectromagnetics [Bioelectromagnetics] 2021 Jan; Vol. 42 (1), pp. 18-26. Date of Electronic Publication: 2020 Sep 15.
نوع المنشور: Journal Article; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8008281 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-186X (Electronic) Linking ISSN: 01978462 NLM ISO Abbreviation: Bioelectromagnetics Subsets: MEDLINE
أسماء مطبوعة: Publication: New York, NY : Wiley-Liss
Original Publication: New York, Liss.
مواضيع طبية MeSH: Antioxidants* , Cytokines*, Humans ; Power Plants ; Vitamin E/pharmacology ; Vitamins
مستخلص: Some epidemiological studies have suggested that exposure to extremely low-frequency magnetic fields (ELF-MFs) can affect the immune system. This study aimed to investigate the effects of antioxidant vitamin consumption on proinflammatory cytokines and biochemical parameters changes. In this randomized, controlled double-blinded trial study, power plant workers exposed to ELF-MFs were enrolled based on inclusion criteria. Ninety-one eligible subjects were randomly divided into four groups: the first group (400 units of vitamin E/day), second group (1,000 mg of vitamin C/day), third group (400 units of vitamin E and 1,000 mg of vitamin C/day), and control group. The intervention was conducted for 3 months. Proinflammatory cytokines interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNF-α), and biochemical parameters (fasting blood sugar, total cholesterol, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol [HDL-c], total protein, and albumin) were measured among the participants' serums, before and after the intervention. The mean level of IL-6 in all vitamin-receiving groups, the mean level of IL-1β in vitamin C and E&C groups, and the mean level of TNF-α in the vitamin C group, decreased significantly after intervention. The arithmetic means of the effect sizes for IL-1β, IL-6, and TNF-α were 0.71, 0.57, and 0.2, respectively. The level of HDL-c in the vitamin E and vitamin E&C groups and the level of triglyceride in the vitamin C group significantly increased after the intervention. Taking antioxidant vitamins can prevent an increase of proinflammatory cytokines induced by prolonged exposure to ELF-MFs. Bioelectromagnetics. 2021;42:18-26. © 2020 Bioelectromagnetics Society.
(© 2020 Bioelectromagnetics Society.)
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معلومات مُعتمدة: 96168 Shahroud University of Medical Sciences
فهرسة مساهمة: Keywords: extremely low-frequency magnetic fields; interleukin-1β; interleukin-6; tumor necrosis factor-α; vitamin C; vitamin E
المشرفين على المادة: 0 (Antioxidants)
0 (Cytokines)
0 (Vitamins)
1406-18-4 (Vitamin E)
تواريخ الأحداث: Date Created: 20200915 Date Completed: 20211025 Latest Revision: 20211025
رمز التحديث: 20231215
DOI: 10.1002/bem.22294
PMID: 32931612
قاعدة البيانات: MEDLINE
الوصف
تدمد:1521-186X
DOI:10.1002/bem.22294