دورية أكاديمية
أعرض في EDS

A high-protein meal does not improve blood pressure or vasoactive biomarker responses to acute exercise in humans.

التفاصيل البيبلوغرافية
العنوان: A high-protein meal does not improve blood pressure or vasoactive biomarker responses to acute exercise in humans.
المؤلفون: Bergia RE; Department of Nutrition Science, Purdue University, 700 West State St, West Lafayette, IN 47907., Campbell WW; Department of Nutrition Science, Purdue University, 700 West State St, West Lafayette, IN 47907. Electronic address: campbellw@purdue.edu., Roseguini BT; Department of Health & Kinesiology, Purdue University, 800 W Stadium Ave, West Lafayette, IN 47907., Kim JE; Food Science and Technology Programme, c/o Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543. Electronic address: chmkje@nus.edu.sg.
المصدر: Nutrition research (New York, N.Y.) [Nutr Res] 2020 Sep; Vol. 81, pp. 97-107. Date of Electronic Publication: 2020 Aug 11.
نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8303331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0739 (Electronic) Linking ISSN: 02715317 NLM ISO Abbreviation: Nutr Res Subsets: MEDLINE
أسماء مطبوعة: Publication: <2004- > : Tarrytown, NY : Elsevier Science
Original Publication: New York : Pergamon Press, c1981-
مواضيع طبية MeSH: Blood Pressure* , Exercise* , Meals*, Dietary Proteins/*administration & dosage, Adult ; Arginine/analogs & derivatives ; Arginine/blood ; Biomarkers/blood ; Cross-Over Studies ; Dietary Fats/administration & dosage ; Double-Blind Method ; Female ; Humans ; Male ; Postprandial Period
مستخلص: Blood pressure (BP) responses to exercise yield prognostic information beyond resting BP. While habitual higher dietary protein intake is associated with reduced resting BP, few studies have assessed the impact of high-protein meals on acute BP and vasoactive biomarker responses to exercise. To test the hypothesis that consuming a higher-protein, lower fat meal (HP; 30 g protein, 17 g fat, 52 g carbohydrate) would attenuate the BP response to exercise and result in a more robust post-exercise hypotensive response compared to a lower-protein, higher-fat meal (LP; 13 g protein, 25 g fat, 54 g carbohydrate), we recruited 31 pre-hypertensive subjects to complete this randomized, double-blind, cross-over acute feeding study. One hundred sixty-five minutes after consuming the test HP or LP meal, subjects exercised on a cycle ergometer at 70% VO 2 max for 30 minutes. Blood pressure was measured prior to the meal and periodically before, during, and after exercise for a 315-minute period. Blood samples were periodically collected to quantify plasma arginine, arginine metabolites (asymmetric dimethylarginine, symmetric dimethylarginine; ADMA, SDMA), endothelin-1, nitrates, and nitrites in a subset of subjects (n = 15) as shown in Supplemental Table S1. Consuming the HP meal did not influence the BP responses to exercise, including the post-exercise return to baseline BP or systolic BP area under the curve. While the HP meal resulted in greater postprandial plasma arginine concentrations, ADMA, SDMA, endothelin-1, nitrates, and nitrites were unaltered. These results suggest that consuming a higher-protein, lower-fat meal does not influence BP or vasoactive biomarker responses to exercise compared to a lower-protein, higher-fat meal.
(Copyright © 2020 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: dietary proteins; hemodynamics; human model; hypertension; period; post-exercise hypotension; postprandial
المشرفين على المادة: 0 (Biomarkers)
0 (Dietary Fats)
0 (Dietary Proteins)
49787G1ULV (symmetric dimethylarginine)
63CV1GEK3Y (N,N-dimethylarginine)
94ZLA3W45F (Arginine)
تواريخ الأحداث: Date Created: 20200919 Date Completed: 20210628 Latest Revision: 20210628
رمز التحديث: 20221213
DOI: 10.1016/j.nutres.2020.08.001
PMID: 32949918
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-0739
DOI:10.1016/j.nutres.2020.08.001