دورية أكاديمية
Allergic sensitization pattern of patients in Brazil.
| العنوان: | Allergic sensitization pattern of patients in Brazil. |
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| المؤلفون: | Aranda CS; Universidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil. Electronic address: aranda@unifesp.br., Cocco RR; Universidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil., Pierotti FF; Universidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil., Sarinho E; Universidade Federal de Pernambuco, Departamento de Pediatria, Recife, PE, Brazil., Sano F; Hospital Nipo Brasileiro, Departamento de Pediatria, São Paulo, SP, Brazil., Porto A; Universidade de Passo Fundo, Departamento de Pediatria, Passo Fundo, RS, Brazil., Rosário N; Universidade Federal do Paraná, Departamento de Pediatria, Curitiba, PR, Brazil., Chong Neto HJ; Universidade Federal do Paraná, Departamento de Pediatria, Curitiba, PR, Brazil., Goudouris E; Universidade Federal do Rio de Janeiro, Departamento de Pediatria, Rio de Janeiro, RJ, Brazil., Moraes LS; Universidade Federal de Mato Grosso, Departamento de Pediatria, Cuiabá, MT, Brazil., Wandalsen NF; Faculdade de Medicina do ABC, Departamento de Pediatria, São Paulo, SP, Brazil., Mallozi MC; Universidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil., Pastorino AC; Universidade de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil., Franco JM; Universidade Federal de Sergipe, Departamento de Pediatria, Aracaju, SE, Brazil., Chavarria ML; Universidade Federal de Goiás, Departamento de Pediatria, Goiânia, GO, Brazil., Borres M; Uppsala University, Department of Maternal and Child Health, Uppsala, Sweden., Solé D; Universidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil. |
| المصدر: | Jornal de pediatria [J Pediatr (Rio J)] 2021 Jul-Aug; Vol. 97 (4), pp. 387-395. Date of Electronic Publication: 2020 Sep 25. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Editora Ltda Country of Publication: Brazil NLM ID: 2985188R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4782 (Electronic) Linking ISSN: 00217557 NLM ISO Abbreviation: J Pediatr (Rio J) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Rio de Janeiro, Brazil : Elsevier Editora Ltda Original Publication: Rio de Janeiro. |
| مواضيع طبية MeSH: | Asthma*, Allergens ; Animals ; Brazil/epidemiology ; Child ; Humans ; Immunoglobulin E ; Pyroglyphidae |
| مستخلص: | Objective: Allergic sensitization is one of the key components for the development of allergies. Polysensitization seems to be related to the persistence and severity of allergic diseases. Furthermore, allergic sensitization has a predictive role in the development of allergies. The aim of this study was to characterize the pattern of sensitization of atopic patients treated at different pediatric allergy referral centers in Brazil. Methods: A nation-wide transversal multicenter study collected data on patients attended in Brazil. Peripheral blood samples were collected to determine the serum levels of allergen-specific IgE. If allergen-specific IgE was higher than 0.1 kUA/L, the following specific components were quantified. Results: A total of 470 individuals were enrolled in the study. Mite sensitization was the most frequent kind in all participants. A high frequency of sensitization to furry animals and grasses featured in the respiratory allergies. Regarding components, there was a predominance of sensitization to Der p 1 and Der p 2. It has been verified that having a food allergy, atopic dermatitis, or multimorbidity are risk factors for the development of more severe allergic disease. Conclusion: Studies on the pattern of allergic sensitization to a specific population offer tools for the more effectual prevention, diagnosis, and treatment of allergic diseases. Sensitization to dust mites house was the most prevalent in the evaluated sample. High rates of sensitization to furry animals also stand out. Patients with food allergy, atopic dermatitis, or multimorbidity appear to be at greater risk for developing more severe allergic diseases. (Copyright © 2020 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.) |
| التعليقات: | Comment in: J Pediatr (Rio J). 2021 Jul-Aug;97(4):363-365. (PMID: 33676885) |
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| فهرسة مساهمة: | Keywords: Allergy; Biomarkers; Children; Prognosis; Sensitization |
| المشرفين على المادة: | 0 (Allergens) 37341-29-0 (Immunoglobulin E) |
| تواريخ الأحداث: | Date Created: 20200928 Date Completed: 20210804 Latest Revision: 20220910 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9432344 |
| DOI: | 10.1016/j.jped.2020.08.005 |
| PMID: | 32986999 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-4782 |
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| DOI: | 10.1016/j.jped.2020.08.005 |