The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals.

التفاصيل البيبلوغرافية
العنوان:	The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals.
المؤلفون:	Bastian FB; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Roux J; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Niknejad A; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Comte A; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Fonseca Costa SS; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., de Farias TM; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Moretti S; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Parmentier G; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., de Laval VR; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Rosikiewicz M; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Wollbrett J; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Echchiki A; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Escoriza A; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Gharib WH; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Gonzales-Porta M; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Jarosz Y; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Laurenczy B; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Moret P; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Person E; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Roelli P; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Sanjeev K; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Seppey M; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Robinson-Rechavi M; Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
المصدر:	Nucleic acids research [Nucleic Acids Res] 2021 Jan 08; Vol. 49 (D1), pp. D831-D847.
نوع المنشور:	Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة:	English
بيانات الدورية:	Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
أسماء مطبوعة:	Publication: 1992- : Oxford : Oxford University Press Original Publication: London, Information Retrieval ltd.
مواضيع طبية MeSH:	Data Curation* , Databases, Genetic, Transcriptome/genetics, Animals ; Gene Expression Regulation ; Molecular Sequence Annotation ; User-Computer Interface
مستخلص:	Bgee is a database to retrieve and compare gene expression patterns in multiple animal species, produced by integrating multiple data types (RNA-Seq, Affymetrix, in situ hybridization, and EST data). It is based exclusively on curated healthy wild-type expression data (e.g., no gene knock-out, no treatment, no disease), to provide a comparable reference of normal gene expression. Curation includes very large datasets such as GTEx (re-annotation of samples as 'healthy' or not) as well as many small ones. Data are integrated and made comparable between species thanks to consistent data annotation and processing, and to calls of presence/absence of expression, along with expression scores. As a result, Bgee is capable of detecting the conditions of expression of any single gene, accommodating any data type and species. Bgee provides several tools for analyses, allowing, e.g., automated comparisons of gene expression patterns within and between species, retrieval of the prefered conditions of expression of any gene, or enrichment analyses of conditions with expression of sets of genes. Bgee release 14.1 includes 29 animal species, and is available at https://bgee.org/ and through its Bioconductor R package BgeeDB. (© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.)
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معلومات مُعتمدة:	U01 CA215010 United States CA NCI NIH HHS
تواريخ الأحداث:	Date Created: 20201010 Date Completed: 20210126 Latest Revision: 20210703
رمز التحديث:	20221213
مُعرف محوري في PubMed:	PMC7778977
DOI:	10.1093/nar/gkaa793
PMID:	33037820
قاعدة البيانات:	MEDLINE

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تدمد:	1362-4962
DOI:	10.1093/nar/gkaa793