Comparative overview of the effects of aerobic and resistance exercise on anxiety-like behavior, cognitive flexibility, and hippocampal synaptic plasticity parameters in healthy rats.

التفاصيل البيبلوغرافية
العنوان:	Comparative overview of the effects of aerobic and resistance exercise on anxiety-like behavior, cognitive flexibility, and hippocampal synaptic plasticity parameters in healthy rats.
المؤلفون:	Segabinazi E; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Gasperini NF; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Faustino AM; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Centeno R; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Santos ASD; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Almeida W; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Bronauth LP; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Marcuzzo S; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil., Pereira LO; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.; Laboratório de Histofisiologia Comparada, Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
المصدر:	Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas [Braz J Med Biol Res] 2020 Oct 09; Vol. 53 (11), pp. e9816. Date of Electronic Publication: 2020 Oct 09 (Print Publication: 2020).
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Associação Brasileira de Divulgação Científica Country of Publication: Brazil NLM ID: 8112917 Publication Model: eCollection Cited Medium: Internet ISSN: 1414-431X (Electronic) Linking ISSN: 0100879X NLM ISO Abbreviation: Braz J Med Biol Res Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: [SP, Brasil : Associação Brasileira de Divulgação Científica, 1981-
مواضيع طبية MeSH:	Physical Conditioning, Animal* , Resistance Training*, Animals ; Anxiety ; Cognition ; Hippocampus ; Male ; Neuronal Plasticity ; Rats ; Rats, Wistar
مستخلص:	Clinical studies show that physical exercise has anxiolytic and pro-cognitive properties for both healthy individuals and psychiatric patients. Most of these data refer to the effects of aerobic exercise. However, other modalities such as resistance exercise deserve more attention because they may also modulate brain function. This study aimed to compare the effects of an aerobic exercise protocol on a treadmill and a resistance exercise protocol on a ladder apparatus on anxiety-like behavior, cognitive flexibility, and neuroplasticity parameters in healthy animals. Adult male Wistar rats were divided into three groups: sedentary control, aerobic training, and resistance training. Subsequently, they were evaluated in the elevated plus-maze (EPM), light-dark box, and modified hole board (mHB) tests. The expressions of synaptophysin and postsynaptic plasticity protein 95 in the dorsal and ventral hippocampus were analyzed by immunofluorescence. The results demonstrated an anxiolytic effect promoted by exercise in the EPM, particularly in the animals submitted to aerobic training, and a mild pro-learning effect of both exercise modalities was observed in the mHB test. All groups showed similar outcomes in the other evaluations. Therefore, the exercise modalities investigated in the present study did not provide considerable modifications to such aspects of the emotional/cognitive functions and neuroplasticity under physiological contexts. Perhaps the two types of exercise acted in neurobiological pathways not analyzed in this study, or the effects may emerge under pathological contexts. These hypotheses should be tested in future studies.
References:	Psychopharmacology (Berl). 1993;113(2):237-42. (PMID: 7855188) Mol Neurobiol. 2019 Jan;56(1):748-760. (PMID: 29796991) Braz J Med Biol Res. 2012 Dec;45(12):1215-20. (PMID: 22930413) Behav Brain Res. 2005 Apr 15;159(1):55-61. (PMID: 15794998) Eur J Neurosci. 2003 Jan;17(1):128-36. (PMID: 12534976) Behav Brain Res. 2003 Feb 17;139(1-2):197-213. (PMID: 12642189) Exp Gerontol. 2013 Feb;48(2):136-9. (PMID: 23201423) Br J Sports Med. 2015 Feb;49(4):248-54. (PMID: 24711660) Neuroscience. 2013 Jun 14;240:1-12. (PMID: 23454542) Behav Brain Res. 2001 Aug 1;122(2):159-67. (PMID: 11334646) Pflugers Arch. 2014 Sep;466(9):1673-87. (PMID: 24647666) Endocrinology. 2014 Oct;155(10):3920-33. (PMID: 25057792) Psychoneuroendocrinology. 2014 Dec;50:106-17. (PMID: 25202830) Dialogues Clin Neurosci. 2015 Sep;17(3):295-303. (PMID: 26487810) Neurology. 2019 Feb 26;92(9):e905-e916. (PMID: 30700591) Front Hum Neurosci. 2019 Jul 31;13:260. (PMID: 31417381) Neuroscience. 2018 Apr 15;376:94-107. (PMID: 29462703) J Exerc Rehabil. 2018 Oct 31;14(5):724-730. (PMID: 30443516) PLoS One. 2019 Dec 3;14(12):e0225940. (PMID: 31794582) Ann Neurosci. 2019 Jan;25(3):121-125. (PMID: 30814820) Science. 2005 Jun 17;308(5729):1792-4. (PMID: 15961670) J Neuroinflammation. 2020 Jan 3;17(1):4. (PMID: 31900170) J Appl Physiol (1985). 2016 Jul 1;121(1):248-54. (PMID: 27283912) Sci Rep. 2019 Sep 23;9(1):13684. (PMID: 31548605) J Anxiety Disord. 2017 Dec;52:43-52. (PMID: 29049901) Acta Psychol (Amst). 2014 Nov;153:13-9. (PMID: 25262058) Brain Res. 2019 Mar 15;1707:27-44. (PMID: 30448443) Int J Sports Med. 2004 Jan;25(1):78-82. (PMID: 14750018) Physiol Behav. 2015 Feb;139:26-33. (PMID: 25446212) Int J Neurosci. 2020 Jun;130(6):541-550. (PMID: 31847639) Brain Imaging Behav. 2020 Oct;14(5):1577-1587. (PMID: 30927200) Sports Med. 2017 Dec;47(12):2521-2532. (PMID: 28819746) Int J Neurosci. 2019 Jun;129(6):551-562. (PMID: 30929591) Physiol Behav. 2014 May 10;130:47-53. (PMID: 24657739) J Bodyw Mov Ther. 2008 Jan;12(1):72-5. (PMID: 19083658) Neuroscience. 2012 Jan 27;202:309-17. (PMID: 22155655) J Nutr Health Aging. 2018;22(8):944-951. (PMID: 30272098)
تواريخ الأحداث:	Date Created: 20201014 Date Completed: 20201201 Latest Revision: 20201201
رمز التحديث:	20231215
مُعرف محوري في PubMed:	PMC7561075
DOI:	10.1590/1414-431X20209816
PMID:	33053097
قاعدة البيانات:	MEDLINE

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تدمد:	1414-431X
DOI:	10.1590/1414-431X20209816