دورية أكاديمية
أعرض في EDS

Disseminated Saksenaea infection in an immunocompromised host associated with a good clinical outcome: a case report and review of the literature.

التفاصيل البيبلوغرافية
العنوان: Disseminated Saksenaea infection in an immunocompromised host associated with a good clinical outcome: a case report and review of the literature.
المؤلفون: Davidson N; Division of Medicine, Royal Darwin Hospital, Darwin, Australia. Natalie.davidson88@gmail.com.; Sullivan and Nicolaides Pathology, Brisbane, Australia. Natalie.davidson88@gmail.com., Campbell K; Division of Medicine, Royal Darwin Hospital, Darwin, Australia., Foroughi F; Department of Pathology, Royal Darwin Hospital, Darwin, Australia., Tayal V; Division of Medicine, Royal Darwin Hospital, Darwin, Australia., Lynar S; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.; Global and Tropical Health Division, Charles Darwin University, Menzies School of Health Research, Darwin, Australia., Crawford LC; National Mycology Reference Centre, Microbiology and Infectious Diseases, SA Pathology, Frome Road, Adelaide, South Australia, Australia., Kidd SE; National Mycology Reference Centre, Microbiology and Infectious Diseases, SA Pathology, Frome Road, Adelaide, South Australia, Australia., Baird R; Department of Pathology, Royal Darwin Hospital, Darwin, Australia., Davies J; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.; Global and Tropical Health Division, Charles Darwin University, Menzies School of Health Research, Darwin, Australia., Meumann EM; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.; Global and Tropical Health Division, Charles Darwin University, Menzies School of Health Research, Darwin, Australia.
المصدر: BMC infectious diseases [BMC Infect Dis] 2020 Oct 14; Vol. 20 (1), pp. 755. Date of Electronic Publication: 2020 Oct 14.
نوع المنشور: Case Reports; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Mucormycosis/*diagnosis , Mucormycosis/*etiology, Aged ; Amphotericin B/therapeutic use ; Antifungal Agents/therapeutic use ; Granulomatosis with Polyangiitis/etiology ; Humans ; Immunocompromised Host ; Male ; Mucormycosis/drug therapy ; Mucormycosis/surgery ; Northern Territory ; Triazoles/therapeutic use
مستخلص: Background: Saksenaea species (spp.) are uncommon causes of mucormycosis but are emerging pathogens mostly associated with trauma and soil contamination often in immunocompetent hosts. Due to lack of sporulation in the laboratory, diagnosis and susceptibility testing is difficult so optimal treatment regimens are unknown.
Case Presentation: A 67 year-old man from the Northern Territory in Australia, with a history of eosinophilic granulomatosis with polyangiitis, developed disseminated Saksenaea infection after initially presenting with symptoms consistent with bacterial pyelonephritis. Despite a delay in diagnosis; with aggressive surgical management and dual therapy with amphotericin B and posaconazole, he survived.
Conclusions: We describe an unusual case of disseminated infection with a favourable outcome to date.
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فهرسة مساهمة: Keywords: Amphotericin B; Disseminated fungal infection; Mucormycosis; Posaconazole
المشرفين على المادة: 0 (Antifungal Agents)
0 (Triazoles)
6TK1G07BHZ (posaconazole)
7XU7A7DROE (Amphotericin B)
SCR Disease Name: Saksenaea infection
تواريخ الأحداث: Date Created: 20201015 Date Completed: 20201109 Latest Revision: 20201210
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7559758
DOI: 10.1186/s12879-020-05459-9
PMID: 33054720
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2334
DOI:10.1186/s12879-020-05459-9