دورية أكاديمية
Disseminated Saksenaea infection in an immunocompromised host associated with a good clinical outcome: a case report and review of the literature.
العنوان: | Disseminated Saksenaea infection in an immunocompromised host associated with a good clinical outcome: a case report and review of the literature. |
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المؤلفون: | Davidson N; Division of Medicine, Royal Darwin Hospital, Darwin, Australia. Natalie.davidson88@gmail.com.; Sullivan and Nicolaides Pathology, Brisbane, Australia. Natalie.davidson88@gmail.com., Campbell K; Division of Medicine, Royal Darwin Hospital, Darwin, Australia., Foroughi F; Department of Pathology, Royal Darwin Hospital, Darwin, Australia., Tayal V; Division of Medicine, Royal Darwin Hospital, Darwin, Australia., Lynar S; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.; Global and Tropical Health Division, Charles Darwin University, Menzies School of Health Research, Darwin, Australia., Crawford LC; National Mycology Reference Centre, Microbiology and Infectious Diseases, SA Pathology, Frome Road, Adelaide, South Australia, Australia., Kidd SE; National Mycology Reference Centre, Microbiology and Infectious Diseases, SA Pathology, Frome Road, Adelaide, South Australia, Australia., Baird R; Department of Pathology, Royal Darwin Hospital, Darwin, Australia., Davies J; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.; Global and Tropical Health Division, Charles Darwin University, Menzies School of Health Research, Darwin, Australia., Meumann EM; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.; Global and Tropical Health Division, Charles Darwin University, Menzies School of Health Research, Darwin, Australia. |
المصدر: | BMC infectious diseases [BMC Infect Dis] 2020 Oct 14; Vol. 20 (1), pp. 755. Date of Electronic Publication: 2020 Oct 14. |
نوع المنشور: | Case Reports; Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: London : BioMed Central, [2001- |
مواضيع طبية MeSH: | Mucormycosis/*diagnosis , Mucormycosis/*etiology, Aged ; Amphotericin B/therapeutic use ; Antifungal Agents/therapeutic use ; Granulomatosis with Polyangiitis/etiology ; Humans ; Immunocompromised Host ; Male ; Mucormycosis/drug therapy ; Mucormycosis/surgery ; Northern Territory ; Triazoles/therapeutic use |
مستخلص: | Background: Saksenaea species (spp.) are uncommon causes of mucormycosis but are emerging pathogens mostly associated with trauma and soil contamination often in immunocompetent hosts. Due to lack of sporulation in the laboratory, diagnosis and susceptibility testing is difficult so optimal treatment regimens are unknown. Case Presentation: A 67 year-old man from the Northern Territory in Australia, with a history of eosinophilic granulomatosis with polyangiitis, developed disseminated Saksenaea infection after initially presenting with symptoms consistent with bacterial pyelonephritis. Despite a delay in diagnosis; with aggressive surgical management and dual therapy with amphotericin B and posaconazole, he survived. Conclusions: We describe an unusual case of disseminated infection with a favourable outcome to date. |
References: | Curr Infect Dis Rep. 2010 Nov;12(6):423-9. (PMID: 21308550) J Fungi (Basel). 2019 Nov 14;5(4):. (PMID: 31739583) Emerg Infect Dis. 2008 Feb;14(2):342-4. (PMID: 18258139) Clin Microbiol Infect. 2016 Sep;22(9):775-781. (PMID: 26806139) J Infect. 1983 Sep;7(2):162-5. (PMID: 6644085) Am J Clin Pathol. 1981 Jul;76(1):116-21. (PMID: 6942651) Nucleic Acids Res. 2016 Jan 4;44(D1):D7-19. (PMID: 26615191) Clin Infect Dis. 2000 Jun;30(6):942-3. (PMID: 10880307) J Mycol Med. 2019 Sep;29(3):260-264. (PMID: 31445820) Antimicrob Agents Chemother. 2002 May;46(5):1581-2. (PMID: 11959605) Med Mycol. 2012 Oct;50(7):710-5. (PMID: 22458251) J Clin Microbiol. 2010 Dec;48(12):4410-6. (PMID: 20926710) Mycopathologia. 2014 Feb;177(1-2):97-101. (PMID: 24178374) Mycopathologia. 2020 Jun;185(3):577-581. (PMID: 32279162) Clin Microbiol Rev. 2011 Apr;24(2):411-45. (PMID: 21482731) Int J Microbiol. 2019 Sep 22;2019:6253829. (PMID: 31662760) Med J Aust. 2008 Nov 3;189(9):519-20. (PMID: 18976196) Sabouraudia. 1985 Apr;23(2):137-40. (PMID: 4012512) J Fungi (Basel). 2019 Mar 21;5(1):. (PMID: 30901907) |
فهرسة مساهمة: | Keywords: Amphotericin B; Disseminated fungal infection; Mucormycosis; Posaconazole |
المشرفين على المادة: | 0 (Antifungal Agents) 0 (Triazoles) 6TK1G07BHZ (posaconazole) 7XU7A7DROE (Amphotericin B) |
SCR Disease Name: | Saksenaea infection |
تواريخ الأحداث: | Date Created: 20201015 Date Completed: 20201109 Latest Revision: 20201210 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC7559758 |
DOI: | 10.1186/s12879-020-05459-9 |
PMID: | 33054720 |
قاعدة البيانات: | MEDLINE |
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