دورية أكاديمية
ENDOPHTHALMITIS PRESENTING AS RETINAL VASCULITIS LESS THAN 24 HOURS AFTER AFLIBERCEPT INJECTION: A CASE REPORT.
| العنوان: | ENDOPHTHALMITIS PRESENTING AS RETINAL VASCULITIS LESS THAN 24 HOURS AFTER AFLIBERCEPT INJECTION: A CASE REPORT. |
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| المؤلفون: | Weinstein JE; Department of Ophthalmology, Wake Forest University School of Medicine, Winston-Salem, North Carolina., Greven MA |
| المصدر: | Retinal cases & brief reports [Retin Cases Brief Rep] 2022 Nov 01; Vol. 16 (6), pp. 685-687. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101298744 Publication Model: Print Cited Medium: Internet ISSN: 1937-1578 (Electronic) Linking ISSN: 19351089 NLM ISO Abbreviation: Retin Cases Brief Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hagerstown, MD : Wolters Kluwer Health, c2007- |
| مواضيع طبية MeSH: | Retinal Vasculitis*/drug therapy , Endophthalmitis*/diagnosis , Endophthalmitis*/etiology , Endophthalmitis*/drug therapy , Eye Infections, Bacterial*/drug therapy, Humans ; Receptors, Vascular Endothelial Growth Factor ; Intravitreal Injections ; Vitrectomy/adverse effects ; Retrospective Studies ; Anti-Bacterial Agents/therapeutic use |
| مستخلص: | Purpose: We describe a case of endophthalmitis caused by Streptococcus salivarius presenting as a retinal vasculitis less than 24 hours after intravitreal injection. Methods: A case report. Results: The patient progressed from a hemorrhagic retinal vasculitis to severe endophthalmitis with no view to the posterior segment within 24 hours. The visual acuity progressed from 20 of 20 preinjection to light perception within less than 48 after injection. Vitreous tap and injection was performed within 24 hours of intravitreal aflibercept injection, followed by pars plana vitrectomy the next day. The final visual acuity was hand motions. Conclusion: Streptococcus salivarius is a virulent organism that may cause an endophthalmitis early after intravitreal injection with an unusual presentation of hemorrhagic retinal vasculitis. A high index of suspicion for infectious endophthalmitis should be maintained for all patients presenting with ocular inflammation and worsening vision in the days after intravitreal injections. |
| References: | Xu K, Chin EK, Bennett SR, et al. Endophthalmitis after intravitreal injection of vascular endothelial growth factor inhibitors: management and visual outcomes. Ophthalmology 2018;125:1279–1286. Kurniawan ED, Rocke JR, Sandhu SS, Allen PJ. Predictors of visual outcome and the role of early vitrectomy in streptococcal endophthalmitis. Clin Exp Ophthalmol 2018;46:424–431. Kuriyan AE, Weiss KD, Flynn HW Jr, et al. Endophthalmitis caused by streptococcal species: clinical settings, microbiology, management, and outcomes. Am J Ophthalmol 2014;157:774.e1. Relhan N, Forster RK, Flynn HW Jr. Endophthalmitis: then and now. Am J Ophthalmol 2018;187:xx–xxvii. Chen E, Lin MY, Cox J, Brown DM. Endophthalmitis after intravitreal injection: the importance of viridans streptococci. Retina 2011;31:1525–1533. |
| المشرفين على المادة: | 15C2VL427D (aflibercept) EC 2.7.10.1 (Receptors, Vascular Endothelial Growth Factor) 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20201015 Date Completed: 20221028 Latest Revision: 20221028 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1097/ICB.0000000000001069 |
| PMID: | 33055554 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-1578 |
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| DOI: | 10.1097/ICB.0000000000001069 |