دورية أكاديمية
Natural History of Adapted Leaman Score Assessing Coronary Artery Disease Progression by Computed Tomography Angiography: A 7-Year Follow-Up Report.
| العنوان: | Natural History of Adapted Leaman Score Assessing Coronary Artery Disease Progression by Computed Tomography Angiography: A 7-Year Follow-Up Report. |
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| المؤلفون: | Hideo-Kajita A; MedStar Washington Hospital Center, Interventional Cardiology Department, USA., Garcia-Garcia HM; MedStar Washington Hospital Center, Interventional Cardiology Department, USA. Electronic address: Hector.M.GarciaGarcia@medstar.net., Rubarth R; Georgetown University School of Medicine, Washington, DC, USA., Wopperer S; MedStar Washington Hospital Center, Interventional Cardiology Department, USA., Ozaki Y; MedStar Washington Hospital Center, Interventional Cardiology Department, USA., Freire AFD; Instituto do Coração (InCor), Universidade de São Paulo, São Paulo, São Paulo, Brazil., Cavalcante R; Instituto do Coração (InCor), Universidade de São Paulo, São Paulo, São Paulo, Brazil., Bittencourt M; Center for Clinical and Epidemiological Research and Division of Internal Medicine, University Hospital, University of São Paulo, São Paulo, São Paulo, Brazil., Dan K; MedStar Washington Hospital Center, Interventional Cardiology Department, USA., Pinheiro TL; Instituto do Coração (InCor), Universidade de São Paulo, São Paulo, São Paulo, Brazil., Falcão BAA; Hospital Do Coração De Messejana, Fortaleza, Ceará, Brazil., Falcao JLA; Hospital Do Coração De Messejana, Fortaleza, Ceará, Brazil., Soares P; Instituto do Coração (InCor), Universidade de São Paulo, São Paulo, São Paulo, Brazil., Ribeiro E; Instituto do Coração (InCor), Universidade de São Paulo, São Paulo, São Paulo, Brazil., Rochitte CE; Instituto do Coração (InCor), Universidade de São Paulo, São Paulo, São Paulo, Brazil., Lemos PA; Instituto do Coração (InCor), Universidade de São Paulo, São Paulo, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil. Electronic address: pedro.lemos@einstein.br. |
| المصدر: | Cardiovascular revascularization medicine : including molecular interventions [Cardiovasc Revasc Med] 2021 Jun; Vol. 27, pp. 38-44. Date of Electronic Publication: 2020 Jul 26. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 101238551 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0938 (Electronic) Linking ISSN: 18780938 NLM ISO Abbreviation: Cardiovasc Revasc Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, NY : Elsevier, c2005- |
| مواضيع طبية MeSH: | Coronary Artery Disease*/diagnostic imaging , Coronary Stenosis* , Plaque, Atherosclerotic*, Computed Tomography Angiography ; Coronary Angiography ; Follow-Up Studies ; Humans ; Predictive Value of Tests ; Risk Assessment ; Tomography, X-Ray Computed |
| مستخلص: | Background: Coronary computed tomographic angiography (CCTA) provides a non-invasive assessment of the coronary artery tree. Computed Tomography - adapted Leaman Score (CT-LeSc) has been shown to be an independent predictor of cardiac events in coronary artery disease (CAD) patients with a score greater than 5 (high). Purpose: To investigate the relationship between CT-LeSc and the progression of CAD and to provide vessel- and segment-level CAD qualification and quantification at baseline and 7-year follow-up. Methods: Patients with multivessel CAD and CCTA assessments at baseline and follow-up were included. The CT-LeSc analysis was performed in a paired fashion. The patient-level scores and the differences between each phase were assessed by 2 analysts in an independent core laboratory. Results: This study analyzed 248 coronary segments from 17 patients with a mean follow-up interval of 7.5 ± 0.6 years. The mean CT-LeSc at baseline and follow-up were 14.6 ± 4.2 and 16.9 ± 1.5, respectively, with an absolute increase of 2.3 ± 1.8. The mean cumulative increase of new lesions was 0.2 ± 0.2 per year. Over time, 14.6% of the non-obstructive lesions became obstructive, and 15.0% of the non-calcified plaques became calcified. There were 29 new lesions found at follow-up, and out of these, 16 were obstructive and 19 were non-calcified. Conclusion: In patients at high risk for cardiac events, as determined by CT-LeSc, there was an increase in CT-LeSc, obstructive lesions, and calcified plaques over the 7-year follow-up period. Most of the new lesions were obstructive and non-calcified. This is the first report showing long-term serial imaging CCTA changes in a high-risk population. Competing Interests: Declaration of competing interest The authors declare that there is no conflict of interest regarding the publication of this article. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Atherosclerosis; Computed tomography adapted Leaman score; Coronary artery disease |
| تواريخ الأحداث: | Date Created: 20201024 Date Completed: 20211022 Latest Revision: 20211022 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.carrev.2020.07.023 |
| PMID: | 33097462 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1878-0938 |
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| DOI: | 10.1016/j.carrev.2020.07.023 |