دورية أكاديمية
Influence of the degree of conversion and Bis-GMA residues of bulk fill resins on tissue toxicity in an subcutaneous model in rats.
| العنوان: | Influence of the degree of conversion and Bis-GMA residues of bulk fill resins on tissue toxicity in an subcutaneous model in rats. |
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| المؤلفون: | Barreto Girão L; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil., Ohana de Lima Martins J; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil.; Department of Clinic Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil., Lemos JVM; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil., Pinto MR; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil., Rolim JPML; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil., Alves E Silva FCF; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil., Saboia VPA; Department of Restorative Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil., Bitu Sousa F; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil., de Barros Silva PG; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil. |
| المصدر: | Journal of applied biomaterials & functional materials [J Appl Biomater Funct Mater] 2020 Jan-Dec; Vol. 18, pp. 2280800020947330. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 101586617 Publication Model: Print Cited Medium: Internet ISSN: 2280-8000 (Electronic) Linking ISSN: 22808000 NLM ISO Abbreviation: J Appl Biomater Funct Mater Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2018- : Thousand Oaks, CA : SAGE Publications Original Publication: Milano : Wichtig Editore |
| مواضيع طبية MeSH: | Dental Materials*, Biocompatible Materials/*chemistry , Bisphenol A-Glycidyl Methacrylate/*chemistry , Composite Resins/*chemistry , Inflammation/*chemically induced, Animals ; Dentin/chemistry ; Disease Models, Animal ; Female ; Hardness ; Injections, Subcutaneous ; Light ; Materials Testing ; Polymerization ; Rats ; Rats, Wistar ; Spectroscopy, Fourier Transform Infrared ; Subcutaneous Tissue ; Surface Properties |
| مستخلص: | Aim: To analyse the influence of the degree of conversion (DC) and light curing residues of different bulk fills (BFs) composites on the inflammatory profile in the subcutaneous tissue of rats. Materials and Methods: Resin disks of BF-resins and their active conventional resins (CR; 3M®, Ivoclar®, and Kerr®) were light-cured at 2 mm (BF-superficial) and 4 mm (BF-deep) thicknesses and analyzed by infrared spectroscopy (FTIR; n = 3/group; DC and light curing residues). Then, the disks were implanted in four quadrants in the subcutaneous tissue of Wistar rats (sham, CR, BF-superficial and RF-deep), and after 7, 14, and 28 days, the animals ( n = 6/day) were euthanized for histological analysis of the intensity of the inflammatory process (scores 0-3). Kruskal-Wallis/Dunn and ANOVA/Bonferroni tests were used ( p < 0.05, Graph Pad Prism 5.0). Results: The DC of CR 3M® did not differ significantly compared to BF-superficial and BF-deep resins ( p = 0.235). The Ivoclar® and Kerr® resins showed a higher DC with CR and BF-superficial compared to the BF-deep ( p = 0.005 and p = 0.011, rctively). Kerr® resins showed a higher Bis-GMA/UDMA ratio, especially in BF-deep resin ( p < 0.05). 3M® and Ivoclar resins did not show high inflammation scores, but for Kerr® BF resins (superficial and deep), the inflammatory process was significantly higher than that in the CR and sham quadrants ( p = 0.031). Conclusion: The tissue inflammatory response after resin inoculation depends on the DC and light curing residues of Bis-GMA. |
| فهرسة مساهمة: | Keywords: Resins; permanent dental restoration; toxicity |
| المشرفين على المادة: | 0 (Biocompatible Materials) 0 (Composite Resins) 0 (Dental Materials) 454I75YXY0 (Bisphenol A-Glycidyl Methacrylate) |
| تواريخ الأحداث: | Date Created: 20201105 Date Completed: 20210920 Latest Revision: 20220418 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1177/2280800020947330 |
| PMID: | 33151768 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2280-8000 |
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| DOI: | 10.1177/2280800020947330 |