دورية أكاديمية
أعرض في EDS

Diabetic polyneuropathy with/out neuropathic pain in Mali: A cross-sectional study in two reference diabetes treatment centers in Bamako (Mali), Western Africa.

التفاصيل البيبلوغرافية
العنوان: Diabetic polyneuropathy with/out neuropathic pain in Mali: A cross-sectional study in two reference diabetes treatment centers in Bamako (Mali), Western Africa.
المؤلفون: Maiga Y; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali.; Department of Neurology, Gabriel Touré Teaching Hospital, Bamako, Mali.; Laboratory of Therapeutics (EA3826), Faculty of Medicine of Nantes, University of Nantes, Nantes, France., Diallo S; Department of Neurology, Gabriel Touré Teaching Hospital, Bamako, Mali., Konipo FDN; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali., Sangho O; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali., Sangaré M; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali., Diallo SH; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali.; Department of Neurology, Gabriel Touré Teaching Hospital, Bamako, Mali., Mahamadou S; Department of Diabetology, Gabriel Touré UHC, Bamako, Mali., Péréon Y; Reference Center of Neuromuscular Diseases Atlantique-Occitanie-Caraïbes, Hôtel-Dieu, UHC of Nantes, Nantes, France., Giumelli B; Faculty of Dental Surgery, University of Nantes, Nantes, France., Coulibaly A; Department of Neurology, Gabriel Touré Teaching Hospital, Bamako, Mali., Daou M; Department of Neurology, Gabriel Touré Teaching Hospital, Bamako, Mali., Traoré Z; Department of Neurology, Hospital du Mali, Bamako, Mali., Sow Sylla D; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali.; Center for Combating Diabetes in Mali (CCD), Bamako, Mali., Albakaye M; Department of Neurology, Gabriel Touré Teaching Hospital, Bamako, Mali., Guinto CO; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali., Ouologem M; Faculty of Dental Surgery, University of Nantes, Nantes, France., Sissoko AS; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali., Traoré HA; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali., Coulibaly SP; Faculty of Medicine, University of Technical Sciences and Technologies, Bamako, Mali., Damier P; Faculty of Medicine, University of Nantes, Nantes, France., Attal N; INSERM U 98, CET, CHU Ambroise Paré, 92100 Boulogne-Billancourt, France., Nizard J; Laboratory of Therapeutics (EA3826), Faculty of Medicine of Nantes, University of Nantes, Nantes, France.; Faculty of Medicine, University of Nantes, Nantes, France.; Federal Pain Palliative Care and Support, Laboratory of Therapeutics, Nantes UHC, Nantes, France.
المصدر: PloS one [PLoS One] 2020 Nov 09; Vol. 15 (11), pp. e0241387. Date of Electronic Publication: 2020 Nov 09 (Print Publication: 2020).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Diabetic Neuropathies/*complications , Diabetic Neuropathies/*therapy , Neuralgia/*complications, Adolescent ; Adult ; Cross-Sectional Studies ; Female ; Health Care Costs ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Mali ; Middle Aged ; Neuralgia/drug therapy ; Neuralgia/economics ; Quality of Life ; Referral and Consultation ; Risk Factors ; Young Adult
مستخلص: Introduction: Diabetic polyneuropathy (DPN) with or without neuropathic pain is a frequent complication of diabetes. This work aimed to determine the prevalence of diabetic polyneuropathy, to describe its epidemiological aspects, and to analyze the therapeutic itinerary of patients with DPN.
Methods: This was a cross-sectional, descriptive study performed synchronously over six months at two major follow-up sites for patients with diabetes in Mali. DPN was diagnosed based on the Michigan Neuropathy Screening Instrument (MNSI). The neuropathic nature of the pain and the quality of life of patients were evaluated by the DN4 and the ED-5D scale, respectively. We used three (3) different questionnaires to collect data from patients (one at inclusion and another during the follow-up consultation) and from the caregivers of patients with DPN.
Results: We included 252 patients with diabetes, and DPN was found to have a healthcare facility-based prevalence of 69.8% (176/252). The sex ratio was approximately three females for every male patient. The patients were mostly 31 to 60 years of age, 83% had type 2 diabetes, and 86.9% had neuropathic pain Approximately half of the patients (48.3%) had autonomic neuropathy and they reported moderate to intense pain, which was mainly described as a burning sensation. The patients exhibited impaired exteroceptive and proprioceptive sensations in 51.7% of cases. The patients smoked tobacco in 3.4% of cases, while 36.6% of the patients were obese and had dyslipidemia. The caregivers clearly indicated that appropriate medications were not readily accessible or available for their patients with DPN.
Conclusion: The healthcare facility-based prevalence of DPN with or without neuropathic pain was high in our cohort. These inexpensive and easy-to-use tools (MNSI, DN4) can be used to adequately diagnose DPN in the African context. In Mali, screening and early treatment of patients at risk of DPN should allow for a reduction of the burden of the disease, while caregivers need to be adequately trained to manage DPN.
Competing Interests: The authors have declared that no competing interests exist.
References: Adv Exp Med Biol. 2001;498:21-6. (PMID: 11900370)
Diabetes Care. 2013 Sep;36(9):2456-65. (PMID: 23970715)
Curr Diab Rep. 2019 May 7;19(6):32. (PMID: 31065863)
Diabetes Care. 1988 Jul-Aug;11(7):592-7. (PMID: 3060328)
J Pain Symptom Manage. 2018 Feb;55(2S):S135-S139. (PMID: 28803088)
Neurology. 1993 Apr;43(4):817-24. (PMID: 8469345)
J Int Med Res. 2014 Aug;42(4):1018-28. (PMID: 24891556)
J Cardiovasc Risk. 2003 Apr;10(2):85-96. (PMID: 12668905)
Diabetes Care. 2004 May;27(5):1047-53. (PMID: 15111519)
Eur J Neurol. 2010 Aug;17(8):1010-8. (PMID: 20298428)
East Afr Med J. 2005 Dec;82(12 Suppl):S163-72. (PMID: 16619728)
Int J Endocrinol. 2015;2015:519032. (PMID: 26000014)
Curr Diabetes Rev. 2019;15(4):340-345. (PMID: 30813879)
Acta Neuropathol. 2001 Apr;101(4):367-74. (PMID: 11355308)
Pan Afr Med J. 2018 Nov 01;31:158. (PMID: 31086614)
J Diabetes Complications. 2017 Aug;31(8):1318-1324. (PMID: 28599823)
Curr Diab Rep. 2014;14(9):528. (PMID: 25139473)
Handb Clin Neurol. 2014;126:97-107. (PMID: 25410217)
Int J Epidemiol. 2017 Oct 1;46(5):1421-1432. (PMID: 28582528)
Ann Neurol. 2012 Jan;71(1):26-39. (PMID: 21698661)
Diabetes Care. 2019 Jan;42(Suppl 1):S124-S138. (PMID: 30559237)
J Diabetes Res. 2017;2017:6943851. (PMID: 28191471)
Handb Clin Neurol. 2014;126:559-78. (PMID: 25410244)
PLoS One. 2017 Feb 9;12(2):e0171223. (PMID: 28182728)
Pain Med. 2007 Sep;8 Suppl 2:S50-62. (PMID: 17714116)
PLoS One. 2017 May 18;12(5):e0176128. (PMID: 28545129)
Diabetes Metab Syndr. 2015 Oct-Dec;9(4):373-8. (PMID: 25470637)
BMJ Open Diabetes Res Care. 2019 Nov 15;7(1):e000497. (PMID: 31798889)
Diabetes Care. 2010 Jan;33(1):174-6. (PMID: 20040675)
Diabetes Care. 2017 Jan;40(1):136-154. (PMID: 27999003)
Popul Health Metr. 2003 Dec 16;1(1):11. (PMID: 14678566)
J Diabetes Complications. 2002 Mar-Apr;16(2):159-64. (PMID: 12039399)
Diabetes Metab Res Rev. 2010 Sep;26(6):433-45. (PMID: 20641142)
Diabetes Metab. 2009 Jun;35(3):206-13. (PMID: 19297223)
Diabetes Metab Res Rev. 2011 Oct;27(7):629-38. (PMID: 21695762)
Mali Med. 2014;29(4):15-20. (PMID: 30049111)
Diabetes Care. 2018 May;41(5):1068-1075. (PMID: 29487078)
Diabet Med. 2012 Jul;29(7):937-44. (PMID: 22417277)
PLoS One. 2013 Sep 13;8(9):e74195. (PMID: 24058527)
BMC Complement Altern Med. 2016 Feb 22;16:71. (PMID: 26906899)
J Diabetes Investig. 2019 Sep;10(5):1148-1157. (PMID: 31222961)
PLoS One. 2019 Feb 4;14(2):e0211449. (PMID: 30716109)
Mayo Clin Proc. 2015 Apr;90(4):532-45. (PMID: 25841257)
Diabetes Metab Res Rev. 2013 Jul;29(5):327-33. (PMID: 23381942)
Diabetes Metab Syndr Obes. 2019 Oct 31;12:2261-2272. (PMID: 31802925)
Diabetes Care. 2010 May;33(5):1090-6. (PMID: 20150297)
J Diabetes Complications. 1992 Jan-Mar;6(1):49-57. (PMID: 1562759)
Pain. 2018 Dec;159(12):2658-2666. (PMID: 30161042)
J Appl Physiol (1985). 2016 Jul 1;121(1):1-6. (PMID: 26989220)
BMC Res Notes. 2016 Jan 12;9:24. (PMID: 26758272)
Diabetes Care. 2010 Jan;33 Suppl 1:S62-9. (PMID: 20042775)
Heart. 2008 Nov;94(11):1376-82. (PMID: 18519551)
Diabetes Care. 1994 Nov;17(11):1281-9. (PMID: 7821168)
Pain. 2020 Mar;161(3):574-583. (PMID: 31693539)
Diabetes Care. 2010 Oct;33(10):2285-93. (PMID: 20876709)
J Diabetes Complications. 2015 Mar;29(2):212-7. (PMID: 25498300)
Int J Diabetes Dev Ctries. 2008 Oct;28(4):101-8. (PMID: 20165596)
Diabetes Care. 2011 Oct;34(10):2220-4. (PMID: 21852677)
Diabete Metab. 1977 Dec;3(4):245-56. (PMID: 598565)
Therapie. 2019 Dec;74(6):633-643. (PMID: 31097329)
Qual Life Res. 2017 Aug;26(8):2067-2078. (PMID: 28343350)
Pain. 2004 Apr;108(3):248-257. (PMID: 15030944)
Handb Clin Neurol. 2014;126:469-87. (PMID: 25410240)
Neuron. 2017 Mar 22;93(6):1296-1313. (PMID: 28334605)
تواريخ الأحداث: Date Created: 20201109 Date Completed: 20201223 Latest Revision: 20231104
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC7652324
DOI: 10.1371/journal.pone.0241387
PMID: 33166296
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0241387