دورية أكاديمية
أعرض في EDS

'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.

التفاصيل البيبلوغرافية
العنوان: 'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.
المؤلفون: Mandal S; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK., Barnett J; Department of Radiology, Royal Free London NHS Foundation Trust, London, UK., Brill SE; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK., Brown JS; UCL Respiratory, University College London, London, UK.; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK., Denneny EK; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK., Hare SS; Department of Radiology, Royal Free London NHS Foundation Trust, London, UK., Heightman M; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK., Hillman TE; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK., Jacob J; Centre for Medical Image Computing, University College London, London, UK.; Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UK., Jarvis HC; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK., Lipman MCI; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK.; UCL Respiratory, University College London, London, UK., Naidu SB; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK., Nair A; Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UK., Porter JC; UCL Respiratory, University College London, London, UK.; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK., Tomlinson GS; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK.; Infection and Immunity, University College London, London, UK., Hurst JR; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK j.hurst@ucl.ac.uk.; UCL Respiratory, University College London, London, UK.
مؤلفون مشاركون: ARC Study Group
المصدر: Thorax [Thorax] 2021 Apr; Vol. 76 (4), pp. 396-398. Date of Electronic Publication: 2020 Nov 10.
نوع المنشور: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: British Medical Assn Country of Publication: England NLM ID: 0417353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3296 (Electronic) Linking ISSN: 00406376 NLM ISO Abbreviation: Thorax Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : British Medical Assn.
مواضيع طبية MeSH: Diagnostic Imaging* , Pandemics* , SARS-CoV-2*, COVID-19/*diagnosis , Lung/*diagnostic imaging, Biomarkers/blood ; COVID-19/blood ; Cross-Sectional Studies ; Female ; Hospitalization/trends ; Humans ; Male ; Middle Aged ; Severity of Illness Index
مستخلص: Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post discharge, 53% reported persistent breathlessness, 34% cough and 69% fatigue. 14.6% had depression. In those discharged with elevated biomarkers, 30.1% and 9.5% had persistently elevated d-dimer and C reactive protein, respectively. 38% of chest radiographs remained abnormal with 9% deteriorating. Systematic follow-up after hospitalisation with COVID-19 identifies the trajectory of physical and psychological symptom burden, recovery of blood biomarkers and imaging which could be used to inform the need for rehabilitation and/or further investigation.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
التعليقات: Comment in: Thorax. 2021 Apr;76(4):324-325. (PMID: 33589513)
References: J Med Virol. 2021 Feb;93(2):1013-1022. (PMID: 32729939)
Thorax. 2005 May;60(5):401-9. (PMID: 15860716)
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معلومات مُعتمدة: United Kingdom WT_ Wellcome Trust; 209553 United Kingdom WT_ Wellcome Trust; MR/N007727/1 United Kingdom MRC_ Medical Research Council; 209553/Z/17/Z United Kingdom WT_ Wellcome Trust
فهرسة مساهمة: Investigator: A Ahmed; A Ahmed; A Bangay; I Barbor; M Barber; J Batty; T Buchan; T Burns; A Chauhan; R Dudley; B Cooper; M Duncan; N Elsaid; R Evans; S Flatau; L Gabriel; J Goldring; H Groombridge; L Healy; N Jain; A Khan; CN Niklewicz; E Ozcan; P Patel; S Patel; A Procter; A Ring; J Robertson; P Sagoe; A Saigal; G Seligmann; R Shah; M Taylor; A Wendruff; H Woodcock
Keywords: respiratory infection; viral infection
المشرفين على المادة: 0 (Biomarkers)
تواريخ الأحداث: Date Created: 20201111 Date Completed: 20210705 Latest Revision: 20231115
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7615158
DOI: 10.1136/thoraxjnl-2020-215818
PMID: 33172844
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-3296
DOI:10.1136/thoraxjnl-2020-215818