دورية أكاديمية
Aflatoxin M 1 in raw cow milk and associated hepatocellular carcinoma risk among dairy farming households in Malawi.
| العنوان: | Aflatoxin M |
|---|---|
| المؤلفون: | Njombwa CA; Department of Agricultural Research Services (DARS), Lunyangwa Agricultural Research Station, P.O. Box 59, Mzuzu, Malawi. njombwachunala@yahoo.co.uk., Moreira V; School of Animal Sciences, Louisiana State University Agricultural Center, Baton Rouge, LA, 70803, USA., Williams C; School of Animal Sciences, Louisiana State University Agricultural Center, Baton Rouge, LA, 70803, USA., Aryana K; School of Nutrition and Food Sciences, Louisiana State University Agricultural Center, Baton Rouge, LA, 70803, USA., Matumba L; Food Technology and Nutrition Group, Lilongwe University of Agriculture and Natural Resources, (LUANAR), Natural Resources College, P.O. Box 143, Lilongwe, Malawi. |
| المصدر: | Mycotoxin research [Mycotoxin Res] 2021 Feb; Vol. 37 (1), pp. 89-96. Date of Electronic Publication: 2020 Nov 20. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 8807334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1867-1632 (Electronic) Linking ISSN: 01787888 NLM ISO Abbreviation: Mycotoxin Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Heidelberg : Springer-Verlag Berlin Original Publication: Mainz, Federal Republic of Germany : Hans W. Schmidt, 1985- |
| مواضيع طبية MeSH: | Aflatoxin M1/*analysis , Carcinoma, Hepatocellular/*etiology , Liver Neoplasms/*etiology , Milk/*chemistry , Raw Foods/*analysis, Adult ; Agriculture ; Animals ; Carcinoma, Hepatocellular/epidemiology ; Cattle ; Child ; Child, Preschool ; Dairying/statistics & numerical data ; Food Contamination/analysis ; Humans ; Liver Neoplasms/epidemiology ; Malawi/epidemiology ; Risk Factors ; Young Adult |
| مستخلص: | In the present study, a total of 112 raw milk samples were collected between October and December of 2018 from dairy farming households in Malawi and analyzed for aflatoxin M1 (AFM1) using VICAM aflatest fluorometry procedure. These data together with the consumption data obtained through a milk consumption frequency questionnaire were used for the calculation of AFM |
| References: | Ahlberg S, Grace D, Kiarie G, Kirino Y, Lindahl J (2018) A risk assessment of aflatoxin M1 exposure in low and mid-income dairy consumers in Kenya. Toxins 10(9):348. https://doi.org/10.3390/toxins10090348. Alonso VA, Monge MP, Larriestra A, Dalcero AM, Cavaglieri LR, Chiacchiera SM (2010) Naturally occurring aflatoxin M1 in raw bulk milk from farm cooling tanks in Argentina. Food Addit Contam: Part A 27:373–379. (PMID: 10.1080/19440040903403362) Awasthi V, Bahman S, Thakur LK, Singh SK, Dua A, Ganguly S (2012) Contaminants in milk and impact of heating: an assessment study. Indian J Public Health 56:96–99. Bilandzic N, Varenina I, Solomun B (2010) Aflatoxin M1 in raw milk in Croatia. Food Control 21:1279–1281. (PMID: 10.1016/j.foodcont.2010.03.003) Cano-Sancho G, Marin S, Ramos AJ, Peris-Vicent J, Sanchis V (2010) Occurrence of aflatoxin M1 and exposure assessment in Catalonia (Spain). Rev Iberoam Micol 27:130–135. (PMID: 10.1016/j.riam.2010.05.003) CEC - Commission of the European Communities (2010) EC Regulation 165/2010. 26.02.2010. Bruxelles: Official Journal of the EC L50/8–12. Available from: https://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2010:050:0008:0012:EN:PDF. Covic N, Hendriks SL (2016) Achieving a nutrition revolution for Africa: the road to healthier diets and optimal nutrition. International Food Policy Research Institute (IFPRI), Washington, DC. https://images.agri-profocus.nl/upload/170629_NamukoloCovic_A-nutrition-revolution-for-Africa1500555365.pdf . Accessed 30 June 2020. Cullen JM, Ruebner BH, Hsieh LS, Hyde DM, Hsieh DP (1987) Carcinogenicity of dietary aflatoxin M1 in male Fischer rats compared to aflatoxin B1. Cancer Res 47:1913–1917. (PMID: 3102052) Driehuis F, Spanjer MC, Scholten JM, te Giffel MC (2008) Occurrence of mycotoxins in feedstuffs of dairy cows and estimation of total dietary intakes. J Dairy Sci 91:4261–4271. (PMID: 10.3168/jds.2008-1093) Duarte SC, Almeida AM, Teixeira AS, Pereira AL, Falcão AC, Pena A, Lino CM (2013) Aflatoxin M1 in marketed milk in Portugal: assessment of human and animal exposure. Food Control 30:411–417. (PMID: 10.1016/j.foodcont.2012.08.002) EC – European Commission (2006) Commission regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. Off J Eur Union L 364:5–24 Last consolidated version available from: https://eurlex.europa.eu/legal-content/DE/AUTO/?uri=CELEX:02006R1881-20180319. EFSA - European Food Safety Authority (2004) Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to aflatoxin B EFSA - European Food Safety Authority (2020) Panel on contaminants in the food chain (CONTAM), risk assessment of aflatoxins in food. EFSA J 18(3):e06040. https://doi.org/10.2903/j.efsa.2020.6040. (PMID: 10.2903/j.efsa.2020.6040) Ezekiel CN, Sulyok M, Warth B, Odebode AC, Krska R (2012) Natural occurrence of mycotoxins in peanut cake from Nigeria. Food Control 27:338–342. (PMID: 10.1016/j.foodcont.2012.04.010) FAO - Food and Agriculture Organization of the United Nations (2004) Worldwide regulations for mycotoxins in food and feed in 2003. Food nutrition, 81. FAO. Available from: http://www.fao.org/3/y5499e/y5499e00.htm. FDA – US Food and Drug Administration (2005) Compliance Policy Guides Sec. 527.400 Whole milk, low fat milk, skim milk-aflatoxin M (CPG 7106.10). Washington, DC: FDA Compliance Policy Guides, 219. Available from: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/cpg-sec-527400-whole-milk-lowfat-milk-skim-milk-aflatoxin-m1. Flores-Flores ME, Lizarraga E, López de Cerain A, González-Peñas E (2015) Presence of mycotoxins in animal milk: a review. Food Control 53:163–176. (PMID: 10.1016/j.foodcont.2015.01.020) Hussein HS, Brasel JM (2001) Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 167:101–134. (PMID: 10.1016/S0300-483X(01)00471-1) IARC - International Agency for Research on Cancer (2012) Aflatoxins. In: Chemical agents and related occupations, Vol. 100F: a review of human carcinogens, pp. 225–248. Available from: https://monographs.iarc.fr/ENG/Monographs/vol100F/mono100F.pdf. IFS - Integrated Farming Systems Project (2013) Baseline survey report. Department of Agriculture Research Services, Malawi. JECFA - Joint FAO/WHO Expert Committee on Food Additives (2001) Safety evaluation of certain mycotoxins in food (WHO food additives series no. 47), 56th meeting of the joint FAO/WHO expert committee on food additives (JECFA), Geneva, international Programme on chemical safety, World Health Organization Available from: http://www.fao.org/3/a-bc528e.pdf. JECFA - Joint FAO/WHO Expert Committee on Food Additives (1999) Evaluation of certain food additives and contaminants (forty-ninth report of the joint FAO/WHO expert committee on food additives). In FAO/WHO expert committee on food additives; FAO/WHO: Geneva, Switzerland. Available from: https://apps.who.int/iris/handle/10665/42142. JECFA - Joint FAO/WHO Expert Committee on Food Additives (2017) Evaluation of certain contaminants in food: eighty-third report of the joint FAO/WHO expert committee on food additives. World Health Organization Available from: https://apps.who.int/iris/handle/10665/254893. Kang’ethe EK, Lang’a KA (2009) Aflatoxin B1 and M1 contamination of animal feeds and milk from urban centers in Kenya. Afr Health Sci 9:218–226. (PMID: 215031723074399) Kirino Y, Makita K, Grace D, Lindahl J (2016) Survey of informal milk retailers in Nairobi, Kenya and prevalence of aflatoxin M1 in marketed milk. Afr J Food Agric Nutr Dev 16:11022–11038. Kuboka MM, Imungi JK, Njue L, Mutua F, Grace D, Lindahl JF (2019) Occurrence of aflatoxin M1 in raw milk traded in peri-urban Nairobi, and the effect of boiling and fermentation. Infect Ecol Epidemiol 9(1):1625703. https://doi.org/10.1080/20008686.2019.1625703. Li H, Xing L, Zhang M, Wang J, Zheng N (2018) The toxic effects of aflatoxin B1 and aflatoxin M1 on kidney through regulating L-Proline and downstream apoptosis. Hindawi BioMed Res 2018:1–11. https://doi.org/10.1155/2018/9074861. (PMID: 10.1155/2018/9074861) Lu PX, Wang JB, Zhang QN, Wu Y, Sun Y, Chen TY (2010) Longitudinal study of aflatoxin exposure in the development of primary liver cancer in patients with chronic hepatitis. Zhonghua Yi Xue Za Zhi 90:1665–1669. (PMID: 20979873) Maleta K, Virtanen S, Espo M, Kulmala T, Ashorn P (2003) Timing of growth faltering in rural Malawi. Arch Dis Child 88:574–578. (PMID: 10.1136/adc.88.7.574) Marchese S, Polo A, Ariano A, Velotto S, Costantini S, Severino L (2018) Aflatoxin B1 and M1: biological properties and their involvement in cancer development. Toxins 10:1–19. Matumba L, Monjerezi M, Van Poucke C, Biswick T, Mwatseteza J, De Saeger S (2013) Evaluation of the bright greenish yellow fluorescence test as a screening technique for aflatoxin-contaminated maize in Malawi. World Mycotoxin J 6:367–373. (PMID: 10.3920/WMJ2013.1563) Matumba L, Sulyok M, Monjerezi M, Biswick T, Krska R (2014) Fungal metabolites diversity in maize and associated human dietary exposures relate to micro-climatic patterns in Malawi. World Mycotoxin J 8:269–282. (PMID: 10.3920/WMJ2014.1773) Matumba L, Kimanya M, Chunga-Sambo W, Munthali M, Ayalew A (2019) Probabilistic dietary based estimation of the burden of aflatoxin-induced hepatocellular carcinoma among adult Malawians. World Mycotoxin J 12:409–419. (PMID: 10.3920/WMJ2018.2346) MBS - Malawi Bureau of Standards (2008) Contaminants and toxins in foods – General standards. MS 302, ICS 67.020. Blantyre, Malawi. Meucci V, Razzuoli E, Soldani G, Massart F (2010) Mycotoxin detection in infant formula milks in Italy. Food Addit Contam 27:64–71. (PMID: 10.1080/02652030903207201) Neal GE, Eaton DL, Judah DJ, Verma A (1998) Metabolism and toxicity of aflatoxins M1 and B1 in human-derived in vitro systems. Toxicol Appl Pharmacol 151:152–158. (PMID: 10.1006/taap.1998.8440) Neuveut C, Wei Y, Buendia MA (2010) Mechanisms of HBV-related hepatocarcinogenesis. J Hepatol 52:594–604. (PMID: 10.1016/j.jhep.2009.10.033) Njombwa CA (2019) Occurrence of aflatoxin and zearalenone in concentrate feeds and milk contamination with aflatoxin M Nkosi MM, Andy SC, Mtegha C (2019) Prevalence and contamination levels of aflatoxins in dairy cattle feeds from five milk bulking groups in Malawi. Afr J Rural Dev 3:883–894. NSO - National Statistical Office [Malawi] and ICF (2017) Malawi demographic and health survey 2015–16. Zomba, Malawi, and Rockville, Maryland, USA: NSO and ICF https://dhsprogram.com/pubs/pdf/FR319/FR319.pdf . Accessed 25 June 2020. Peng K, Chen C (2009) Prevalence of aflatoxin M1 in Milk and its potential liver cancer risk in Taiwan. J Food Prot 72:1025–1029. (PMID: 10.4315/0362-028X-72.5.1025) Reddy KR, Salleh B, Saad B, Abbas HK, Abel CA, Shier WT (2010) An overview of mycotoxin contamination in foods and its implications for human health. Toxin Rev 29:3–26. Sadler K, Catley A (2009) Milk matters: improving health and nutritional status of children in pastoralist communities. https://www.ennonline.net/page/renderforpdf/4001 . Accessed 26 September 2020. Schweitzer A, Horn J, Mikolajczyk RT, Krause G, Ott JJ (2015) Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013. Lancet 386:1546–1555. (PMID: 10.1016/S0140-6736(15)61412-X) Sherif OS, Salama EE, Abdel-Wahhab MA (2009) Mycotoxins and child health: the need for health risk assessment. Int J Hyg Environ Health 212:347–368. (PMID: 10.1016/j.ijheh.2008.08.002) Streit E, Schwab C, Sulyok M, Naehrer K, Krska R, Schatzmayr G (2013) Multi-mycotoxin screening reveals the occurrence of 139 different secondary metabolites in feed and feed ingredients. Toxins 5:504–523. (PMID: 10.3390/toxins5030504) Sun Z, Lu P, Gail MH, Pee D, Zhang Q, Ming L, Wang J, Wu Y, Liu G (1999) Increased risk of hepatocellular carcinoma in male hepatitis B surface antigen carriers with chronic hepatitis who have detectable urinary aflatoxin metabolite M1. Hepatology 30:379–383. (PMID: 10.1002/hep.510300204) Tebug SF, Chikagwa-Malunga S, Wiedemann S (2012) On-farm evaluation of dairy farming innovations uptake in northern Malawi. Livest Res Rural Dev 24:1–9. Udovicki B, Djekic I, Kalogianni EP, Rajkovic A (2019) Exposure assessment and risk characterization of aflatoxin M1 intake through consumption of milk and yoghurt by student population in Serbia and Greece. Toxins 11(4):205. https://doi.org/10.3390/toxins11040205. VICAM (2014) AflaTest, AflaM1, ZearalaTest and DONtest Instruction manuals. Available from: http://vicam.com . Accessed 10 January 2020. Walpole SC, Prieto-Merino D, Edwards P, Cleland J, Stevens G, Roberts I (2012) The weight of nations: an estimation of adult human biomass. BMC Public Health 12:439. https://doi.org/10.1186/1471-2458-12-439. Xiang X, Qin HG, You XM, Wang YY, Qi LN, Ma L, Xiang BD, Zhong JH, Li LQ (2017) Expression of P62 in hepatocellular carcinoma involving hepatitis B virus infection and aflatoxin B1 exposure. Cancer Med 6:2357–2369. https://doi.org/10.1002/cam4.1176. (PMID: 10.1002/cam4.1176289412115633547) |
| معلومات مُعتمدة: | RC102095 United States Agency for International Development |
| فهرسة مساهمة: | Keywords: Aflatoxin M1; Cancer risk; Dairy farming; Dietary exposure; Hepatocellular carcinoma; Raw milk |
| المشرفين على المادة: | 6795-23-9 (Aflatoxin M1) |
| تواريخ الأحداث: | Date Created: 20201120 Date Completed: 20210805 Latest Revision: 20210805 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1007/s12550-020-00417-5 |
| PMID: | 33216318 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1867-1632 |
|---|---|
| DOI: | 10.1007/s12550-020-00417-5 |