دورية أكاديمية
Charge-Based Separation of Micro- and Nanoparticles.
العنوان: | Charge-Based Separation of Micro- and Nanoparticles. |
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المؤلفون: | Ho BD; Division of Solid State Physics and NanoLund, Physics Department, Lund University, P.O. Box 118, 22100 Lund, Sweden., Beech JP; Division of Solid State Physics and NanoLund, Physics Department, Lund University, P.O. Box 118, 22100 Lund, Sweden., Tegenfeldt JO; Division of Solid State Physics and NanoLund, Physics Department, Lund University, P.O. Box 118, 22100 Lund, Sweden. |
المصدر: | Micromachines [Micromachines (Basel)] 2020 Nov 18; Vol. 11 (11). Date of Electronic Publication: 2020 Nov 18. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101640903 Publication Model: Electronic Cited Medium: Print ISSN: 2072-666X (Print) Linking ISSN: 2072666X NLM ISO Abbreviation: Micromachines (Basel) Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI, [2010]- |
مستخلص: | Deterministic Lateral Displacement (DLD) is a label-free particle sorting method that separates by size continuously and with high resolution. By combining DLD with electric fields (eDLD), we show separation of a variety of nano and micro-sized particles primarily by their zeta potential. Zeta potential is an indicator of electrokinetic charge-the charge corresponding to the electric field at the shear plane-an important property of micro- and nanoparticles in colloidal or separation science. We also demonstrate proof of principle of separation of nanoscale liposomes of different lipid compositions, with strong relevance for biomedicine. We perform careful characterization of relevant experimental conditions necessary to obtain adequate sorting of different particle types. By choosing a combination of frequency and amplitude, sorting can be made sensitive to the particle subgroup of interest. The enhanced displacement effect due to electrokinetics is found to be significant at low frequency and for particles with high zeta potential. The effect appears to scale with the square of the voltage, suggesting that it is associated with either non-linear electrokinetics or dielectrophoresis (DEP). However, since we observe large changes in separation behavior over the frequency range at which DEP forces are expected to remain constant, DEP can be ruled out. |
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معلومات مُعتمدة: | 607350 Seventh Framework Programme; 801367 Horizon 2020 Framework Programme; 634890 Horizon 2020 Framework Programme; 2016-05739 Vetenskapsrådet |
فهرسة مساهمة: | Keywords: charge-based separation; electrokinetic deterministic lateral displacement |
تواريخ الأحداث: | Date Created: 20201121 Latest Revision: 20240407 |
رمز التحديث: | 20240407 |
مُعرف محوري في PubMed: | PMC7702211 |
DOI: | 10.3390/mi11111014 |
PMID: | 33218201 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2072-666X |
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DOI: | 10.3390/mi11111014 |