دورية أكاديمية
أعرض في EDS

Outcomes and risk factors for failure after trabeculectomy in Taiwanese patients: medical chart reviews from 2006 to 2017.

التفاصيل البيبلوغرافية
العنوان: Outcomes and risk factors for failure after trabeculectomy in Taiwanese patients: medical chart reviews from 2006 to 2017.
المؤلفون: Chiu HI; Department of Ophthalmology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan., Su HI; Department of Ophthalmology, En Chu Kong Hospital, New Taipei City, Taiwan., Ko YC; Department of Ophthalmology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan jlliu@vghtpe.gov.tw koyc@vghtpe.gov.tw.; Medicine, National Yang-Ming University, Taipei, Taiwan., Liu CJ; Department of Ophthalmology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan jlliu@vghtpe.gov.tw koyc@vghtpe.gov.tw.; Medicine, National Yang-Ming University, Taipei, Taiwan.
المصدر: The British journal of ophthalmology [Br J Ophthalmol] 2022 Mar; Vol. 106 (3), pp. 362-367. Date of Electronic Publication: 2020 Nov 23.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 0421041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2079 (Electronic) Linking ISSN: 00071161 NLM ISO Abbreviation: Br J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Jan. 1992- : London : BMJ Pub. Group
Original Publication: 1917-Dec. 1991: London : British Medical Association
مواضيع طبية MeSH: Glaucoma*/drug therapy , Trabeculectomy*/adverse effects, Adult ; Aged ; Follow-Up Studies ; Humans ; Intraocular Pressure ; Middle Aged ; Mitomycin/therapeutic use ; Retrospective Studies ; Risk Factors ; Treatment Outcome
مستخلص: Aims: To determine long-term outcomes and risk factors for failure after mitomycin C (MMC)-augmented initial trabeculectomy (IT) in Taiwanese patients.
Methods: We reviewed medical records of patients with glaucoma undergoing IT during December 2006-December 2016. We defined complete success as an intraocular pressure (IOP) of >5 or ≤21 mm Hg or IOP reduction of ≥20% from baseline without supplemental medications and qualified success as the aforementioned IOP levels with or without supplemental medications. Kaplan-Meier survival and Cox proportional analyses evaluated success rates and risk factors for failure, respectively.
Results: We enrolled 190 patients (237 eyes; mean age: 54.0±15.3 years; mean postoperative follow-up period: 68.4±35.1 months). Mean IOP and glaucoma medications decreased from 22.2±10.8 to 14.4±5.2 mm Hg (p<0.001) and 3.0±0.7 to 1.8±1.2 (p=0.015), respectively, at the last visit. Cumulative qualified success rates were 93.9%, 93.0%, 86.5% and 67.1% at the 1, 2, 5 and 10 years follow-up, respectively; however, only 7.7% of the eyes reached complete success at the last visit. Eyes with poor preoperative visual acuity were associated with low qualified success rates (HR=1.689, p=0.027); patients aged >70 years had higher complete success rates than did those aged ≤70 years. Five cases (2.11%) exhibited bleb-associated complications.
Conclusion: Despite satisfactory long-term success rates, most eyes needed medication for IOP control, supporting the notion of predisposed scarring vitality in patients of Chinese ethnicity following MMC-augmented trabeculectomy.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.)
فهرسة مساهمة: Keywords: glaucoma; intraocular pressure
المشرفين على المادة: 50SG953SK6 (Mitomycin)
تواريخ الأحداث: Date Created: 20201124 Date Completed: 20220422 Latest Revision: 20220422
رمز التحديث: 20221213
DOI: 10.1136/bjophthalmol-2020-317303
PMID: 33229342
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-2079
DOI:10.1136/bjophthalmol-2020-317303