دورية أكاديمية
Effect of High-Dose vs Standard-Dose Vitamin D 3 Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial.
العنوان: | Effect of High-Dose vs Standard-Dose Vitamin D |
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المؤلفون: | Brown JC; Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.; LSU Health Sciences Center, New Orleans School of Medicine, New Orleans, LA 70012, USA.; Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70012, USA., Rosenthal MH; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Ma C; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Zhang S; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Nimeiri HS; Division of Hematology Oncology, Department of Medicine, Northwestern University, Chicago, IL 60611, USA., McCleary NJ; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Abrams TA; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Yurgelun MB; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Cleary JM; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Rubinson DA; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Schrag D; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Bullock AJ; Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Allen J; Massachusetts General Hospital, Boston, MA 02114, USA., Zuckerman D; St Luke's Mountain States Tumor Institute, Boise, ID 83712, USA., Chan E; Vanderbilt University Medical Center, Nashville, TN 37232, USA., Chan JA; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Wolpin B; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Constantine M; Dana-Farber at Milford Regional Medical Center, Milford, MA 01757, USA., Weckstein DJ; New Hampshire Oncology Hematology, Hookset, NH 03106, USA., Faggen MA; Dana-Farber at South Shore Hospital, South Weymouth, MA 02190, USA., Thomas CA; New England Cancer Specialists, Scarborough, ME 04074, USA., Kournioti C; Newton-Wellesley Hospital, Newton, MA 02462, USA., Yuan C; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Zheng H; Massachusetts General Hospital, Boston, MA 02114, USA., Hollis BW; Department of Pediatrics, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA., Fuchs CS; Yale Cancer Center, New Haven, CT 06510, USA., Ng K; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA., Meyerhardt JA; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. |
المصدر: | Cancers [Cancers (Basel)] 2020 Nov 20; Vol. 12 (11). Date of Electronic Publication: 2020 Nov 20. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI |
مستخلص: | Skeletal muscle and adipose tissue express the vitamin D receptor and may be a mechanism through which vitamin D supplementation slows cancer progression and reduces cancer death. In this exploratory analysis of a double-blind, multicenter, randomized phase II clinical trial, 105 patients with advanced or metastatic colorectal cancer who were receiving chemotherapy were randomized to either high-dose vitamin D |
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معلومات مُعتمدة: | P50CA127003 United States CA NCI NIH HHS; P30-DK072476 United States DK NIDDK NIH HHS; R25-CA203650 United States CA NCI NIH HHS; P30 DK072476 United States DK NIDDK NIH HHS; R00 CA218603 United States CA NCI NIH HHS; U54 GM104940 United States GM NIGMS NIH HHS; R01 CA205406 United States CA NCI NIH HHS; R01 CA169141 United States CA NCI NIH HHS; R01CA118553 United States CA NCI NIH HHS; U54-GM104940 National Institute of General Medicine Sciences; R01CA205406 United States CA NCI NIH HHS; R00-CA218603 United States CA NCI NIH HHS; R01 CA118553 United States CA NCI NIH HHS |
فهرسة مساهمة: | Keywords: adipose tissue; cholecalciferol; colorectal neoplasms; mediation; prognosis; randomized; skeletal muscle |
تواريخ الأحداث: | Date Created: 20201125 Latest Revision: 20210721 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC7699725 |
DOI: | 10.3390/cancers12113451 |
PMID: | 33233566 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2072-6694 |
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DOI: | 10.3390/cancers12113451 |