تقرير
Ceftiofur Side Effect in a Mare-Case Report.
| العنوان: | Ceftiofur Side Effect in a Mare-Case Report. |
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| المؤلفون: | Pradella GD; Universidade Federal do Pampa (UNIPAMPA), Uruguaiana, RS. Electronic address: gabrieladowich@hotmail.com., Taschetto PM; Master's Student at Universidade Federal do Pampa (UNIPAMPA), Uruguaiana, RS., Duarte CA; Researcher Teacher at Universidade Federal do Pampa (UNIPAMPA), Uruguaiana, RS., da Silva Azevedo M; Researcher Teacher at Universidade Federal do Pampa (UNIPAMPA), Uruguaiana, RS., Góss GC; Master's Student at Universidade Federal do Pampa (UNIPAMPA), Uruguaiana, RS. |
| المصدر: | Journal of equine veterinary science [J Equine Vet Sci] 2020 Dec; Vol. 95, pp. 103295. Date of Electronic Publication: 2020 Oct 12. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 8216840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0737-0806 (Print) Linking ISSN: 07370806 NLM ISO Abbreviation: J Equine Vet Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2003- : New York : Elsevier Original Publication: [Wildomar, CA : William E. Jones, c1981- |
| مواضيع طبية MeSH: | Drug-Related Side Effects and Adverse Reactions*/veterinary , Horse Diseases*, Animals ; Anti-Bacterial Agents/adverse effects ; Cephalosporins/adverse effects ; Female ; Horses |
| مستخلص: | Adverse drug reactions in horses are rare. The antimicrobials are in the list of the most common drugs associated with reaction in horses. The aim of this report is to describe the clinical presentation of an adverse drug reaction after the intramuscular administration of ceftiofur hydrochloride. A 5-year-old crioulo broodmare at one day postpartum presented signs of difficulty to walk, positive pulse in the four limbs, and heart rate of 80 beats per minute (bpm), with a history of fighting with another mare. The clinical suspicions were rhabdomyolysis and laminitis. Initially a dose of flunixin meglumine was administrated intravenous to prevent an endotoxemia. On the same day, the blood collection showed an elevated number of white blood cells, predominantly neutrophils and monocytes. An antimicrobial treatment with ceftiofur hydrochloride at a dose of 2.2 mg/kg intramuscular was applied. At the first day, the mare does not show signs of drug side effect. However, 24 hours later, in the second application, the patient presents incoordination, dizziness, and loss of equilibrium. At the same time, dexamethasone was administrated. The signs were reverted, and the mare was normal after the reaction. The treatment with ceftiofur was changed to enrofloxacin, and the animal had a complete recovery. These drug reactions are not common in the routine of equine clinical practitioners, but they cause a great preoccupation for the owner and the veterinarian. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Allergic; Cephalosporin; Equine; Hypersensitivity |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (Cephalosporins) 83JL932I1C (ceftiofur) |
| تواريخ الأحداث: | Date Created: 20201205 Date Completed: 20210323 Latest Revision: 20210323 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.jevs.2020.103295 |
| PMID: | 33276911 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0737-0806 |
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| DOI: | 10.1016/j.jevs.2020.103295 |