دورية أكاديمية

Prevalence of malignant neoplastic oral lesions among children and adolescents: A systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Prevalence of malignant neoplastic oral lesions among children and adolescents: A systematic review and meta-analysis.
المؤلفون: de Paula DS; Post-graduate program in Clinic Dentistry, Federal University of Ceará, Fortaleza, Brazil., Nóbrega Malta CE; Post-graduate program in Clinic Dentistry, Federal University of Ceará, Fortaleza, Brazil., de Brito WH; UniNassau University Center, Fortaleza, Brazil., Mota Lemos JV; Post-graduate program in Dental Sciences, Unichristus, Fortaleza, Brazil., Cetira Fillho EL; Post-graduate program in Clinic Dentistry, Federal University of Ceará, Fortaleza, Brazil.; UniNassau University Center, Fortaleza, Brazil.; Post-graduate program in Dental Sciences, Unichristus, Fortaleza, Brazil., Gurgel Costa FW; Post-graduate program in Clinic Dentistry, Federal University of Ceará, Fortaleza, Brazil., Nunes Alves APN; Post-graduate program in Clinic Dentistry, Federal University of Ceará, Fortaleza, Brazil., de Barros Silva PG; Post-graduate program in Clinic Dentistry, Federal University of Ceará, Fortaleza, Brazil.; Post-graduate program in Dental Sciences, Unichristus, Fortaleza, Brazil.
المصدر: International journal of paediatric dentistry [Int J Paediatr Dent] 2021 Jul; Vol. 31 (4), pp. 504-519. Date of Electronic Publication: 2021 Mar 15.
نوع المنشور: Journal Article; Meta-Analysis; Review; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9107511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-263X (Electronic) Linking ISSN: 09607439 NLM ISO Abbreviation: Int J Paediatr Dent
أسماء مطبوعة: Original Publication: Oxford : Blackwell Scientific Publications, c1991-
مواضيع طبية MeSH: Mouth* , Neoplasms*, Adolescent ; Child ; Cross-Sectional Studies ; Humans ; Prevalence
مستخلص: Background: Malignant neoplasms that affect children and adolescents are predominantly embryonic and generally affect blood system cells and supporting tissues.
Aim: This study aimed to summarize the scientific evidence about the prevalence of malignant lesions in the oral cavity of children and adolescents.
Design: In this systematic review and meta-analysis (PROSPERO CRD42020158338), data were obtained from seven databases and the gray literature. Cross-sectional observational studies on the prevalence of biopsied oral pediatric malignancies were included. The Newcastle-Ottawa Scale assessed the quality of the included studies, and the GRADE approach evaluated the evidence certainty. The meta-analysis prevalence was calculated using MedCalc® software, adopting a 95% confidence level (CI; random-effect model).
Results: Forty-two studies were included in the meta-analysis. Of the 64,522 biopsies, the prevalence of malignant lesions was 1.93% (n = 1,100; 95% CI = 1.21%-2.80%). Countries with a low socioeconomic profile showed the highest prevalence. The sample size did not influence the prevalence of oral malignancies, and unspecified lymphomas (12.08%; 95% CI = 5.73%-20.37%) and rhabdomyosarcoma (10.53%; 95% CI = 7.28%-14.30%) were the most common lesions.
Conclusions: Oral malignant lesions biopsied in children and adolescents had a prevalence of <3%, and lymphomas and sarcomas were the most prevalent lesions.
(© 2021 BSPD, IAPD and John Wiley & Sons Ltd.)
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فهرسة مساهمة: Keywords: adolescent; child; lymphoma; mouth neoplasms; prevalence
تواريخ الأحداث: Date Created: 20201208 Date Completed: 20210622 Latest Revision: 20210622
رمز التحديث: 20240829
DOI: 10.1111/ipd.12765
PMID: 33289182
قاعدة البيانات: MEDLINE
الوصف
تدمد:1365-263X
DOI:10.1111/ipd.12765