دورية أكاديمية

Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease.

التفاصيل البيبلوغرافية
العنوان: Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease.
المؤلفون: Saunders DC; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Messmer J; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Kusmartseva I; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, Diabetes Institute, University of Florida, Gainesville, FL, USA., Beery ML; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, Diabetes Institute, University of Florida, Gainesville, FL, USA., Yang M; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, Diabetes Institute, University of Florida, Gainesville, FL, USA., Atkinson MA; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pediatrics, College of Medicine, Diabetes Institute, University of Florida, Gainesville, FL, USA., Powers AC; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; VA Tennessee Valley Healthcare System, Nashville, TN, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Cartailler JP; Creative Data Solutions Shared Resource, Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA., Brissova M; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
المصدر: Patterns (New York, N.Y.) [Patterns (N Y)] 2020 Oct 05; Vol. 1 (8), pp. 100120. Date of Electronic Publication: 2020 Oct 05 (Print Publication: 2020).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101767765 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3899 (Electronic) Linking ISSN: 26663899 NLM ISO Abbreviation: Patterns (N Y) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [New York] : Elsevier Inc., [2020]-
مستخلص: Human tissue phenotyping generates complex spatial information from numerous imaging modalities, yet images typically become static figures for publication, and original data and metadata are rarely available. While comprehensive image maps exist for some organs, most resources have limited support for multiplexed imaging or have non-intuitive user interfaces. Therefore, we built a Pancreatlas resource that integrates several technologies into a unique interface, allowing users to access richly annotated web pages, drill down to individual images, and deeply explore data online. The current version of Pancreatlas contains over 800 unique images acquired by whole-slide scanning, confocal microscopy, and imaging mass cytometry, and is available at https://www.pancreatlas.org. To create this human pancreas-specific biological imaging resource, we developed a React-based web application and Python-based application programming interface, collectively called Flexible Framework for Integrating and Navigating Data (FFIND), which can be adapted beyond Pancreatlas to meet countless imaging or other structured data-management needs.
Competing Interests: The authors declare no competing interests.
(© 2020 The Authors.)
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فهرسة مساهمة: Keywords: application programming interface; data integration; data publication and archiving; diabetes; human pancreas development; imaging databases; microscopy; open source; pancreas imaging; software; web resource
تواريخ الأحداث: Date Created: 20201209 Latest Revision: 20201218
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7691395
DOI: 10.1016/j.patter.2020.100120
PMID: 33294866
قاعدة البيانات: MEDLINE
الوصف
تدمد:2666-3899
DOI:10.1016/j.patter.2020.100120