دورية أكاديمية
Microglial G i -dependent dynamics regulate brain network hyperexcitability.
| العنوان: | Microglial G |
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| المؤلفون: | Merlini M; Gladstone Institutes, San Francisco, CA, USA., Rafalski VA; Gladstone Institutes, San Francisco, CA, USA., Ma K; Gladstone Institutes, San Francisco, CA, USA., Kim KY; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA., Bushong EA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA., Rios Coronado PE; Gladstone Institutes, San Francisco, CA, USA., Yan Z; Gladstone Institutes, San Francisco, CA, USA., Mendiola AS; Gladstone Institutes, San Francisco, CA, USA., Sozmen EG; Gladstone Institutes, San Francisco, CA, USA.; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Ryu JK; Gladstone Institutes, San Francisco, CA, USA.; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Haberl MG; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA., Madany M; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA., Sampson DN; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA., Petersen MA; Gladstone Institutes, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Bardehle S; Gladstone Institutes, San Francisco, CA, USA., Tognatta R; Gladstone Institutes, San Francisco, CA, USA., Dean T Jr; Gladstone Institutes, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Acevedo RM; Gladstone Institutes, San Francisco, CA, USA., Cabriga B; Gladstone Institutes, San Francisco, CA, USA., Thomas R; Gladstone Institutes, San Francisco, CA, USA., Coughlin SR; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Ellisman MH; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA., Palop JJ; Gladstone Institutes, San Francisco, CA, USA.; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Akassoglou K; Gladstone Institutes, San Francisco, CA, USA. kakassoglou@gladstone.ucsf.edu.; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. kakassoglou@gladstone.ucsf.edu. |
| المصدر: | Nature neuroscience [Nat Neurosci] 2021 Jan; Vol. 24 (1), pp. 19-23. Date of Electronic Publication: 2020 Dec 14. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2002->: New York, NY : Nature Publishing Group Original Publication: New York, NY : Nature America Inc., c1998- |
| مواضيع طبية MeSH: | G-Protein-Coupled Receptor Kinase 1/*physiology , Microglia/*physiology , Nerve Net/*physiology, Animals ; Calcium Signaling ; Cell Movement ; Convulsants ; Electroencephalography ; Immunologic Surveillance ; Mice ; Microglia/enzymology ; Microglia/ultrastructure ; Nervous System Diseases/physiopathology ; Nervous System Physiological Phenomena ; Pilocarpine ; Seizures/physiopathology ; Signal Transduction ; rho GTP-Binding Proteins/metabolism |
| مستخلص: | Microglial surveillance is a key feature of brain physiology and disease. Here, we found that G |
| التعليقات: | Comment in: Epilepsy Curr. 2021 Apr 5;:15357597211004568. (PMID: 33820468) |
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| معلومات مُعتمدة: | K99 AG062776 United States AG NIA NIH HHS; R35 NS097976 United States NS NINDS NIH HHS; RF1 AG064926 United States AG NIA NIH HHS; TL1 TR001871 United States TR NCATS NIH HHS; F32 NS096920 United States NS NINDS NIH HHS; R01 AG047313 United States AG NIA NIH HHS; U24 NS120055 United States NS NINDS NIH HHS; C06 RR018928 United States RR NCRR NIH HHS; RF1 AG062234 United States AG NIA NIH HHS; T32 AI007334 United States AI NIAID NIH HHS; K02 NS110973 United States NS NINDS NIH HHS; R24 GM137200 United States GM NIGMS NIH HHS; S10 OD021784 United States OD NIH HHS |
| المشرفين على المادة: | 0 (Convulsants) 01MI4Q9DI3 (Pilocarpine) EC 2.7.11.14 (G-Protein-Coupled Receptor Kinase 1) EC 2.7.11.14 (Grk1 protein, mouse) EC 3.6.5.2 (rho GTP-Binding Proteins) |
| تواريخ الأحداث: | Date Created: 20201215 Date Completed: 20210308 Latest Revision: 20220421 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8118167 |
| DOI: | 10.1038/s41593-020-00756-7 |
| PMID: | 33318667 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1546-1726 |
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| DOI: | 10.1038/s41593-020-00756-7 |