دورية أكاديمية
Spondylitis-psoriasis-enthesitis-enterocolitis-dactylitis-uveitis-peripheral synovitis (SPEED-UP) treatment.
| العنوان: | Spondylitis-psoriasis-enthesitis-enterocolitis-dactylitis-uveitis-peripheral synovitis (SPEED-UP) treatment. |
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| المؤلفون: | Brüner M; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Biomedicine, Aarhus University, Denmark., Dige A; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Denmark., Loft AG; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Rheumatology, Aarhus University Hospital, Denmark., Laurberg TB; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Rheumatology, Aarhus University Hospital, Denmark., Agnholt JS; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Denmark., Clemmensen K; Department of Ophthalmology, Aarhus University Hospital, Denmark., McInnes I; Institute of Infection, Immunity and Inflammation, University of Glascow, Denmark., Lories R; Skeletal Biology and Engineering Research Center, KU Leuven, Denmark., Iversen L; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark., Hjuler KF; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark. Electronic address: dochjuler@gmail.com., Kragstrup TW; National Center of Autoimmune Diseases, Aarhus University Hospital, Denmark; Department of Biomedicine, Aarhus University, Denmark; Department of Rheumatology, Aarhus University Hospital, Denmark. Electronic address: kragstrup@biomed.au.dk. |
| المصدر: | Autoimmunity reviews [Autoimmun Rev] 2021 Feb; Vol. 20 (2), pp. 102731. Date of Electronic Publication: 2020 Dec 14. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128967 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-0183 (Electronic) Linking ISSN: 15689972 NLM ISO Abbreviation: Autoimmun Rev Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam ; New York : Elsevier, c2002- |
| مواضيع طبية MeSH: | Arthritis, Psoriatic*/complications , Arthritis, Psoriatic*/drug therapy , Enterocolitis* , Psoriasis* , Synovitis*/diagnosis , Synovitis*/drug therapy , Uveitis*/diagnosis , Uveitis*/drug therapy , Uveitis*/etiology, Humans |
| مستخلص: | Axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), psoriasis, inflammatory bowel disease (IBD), and noninfectious uveitis form a distinct group among the immune mediated inflammatory diseases. Thus, many patients suffer from more than one of these disease manifestations. Here, we will use the term spondylitis-psoriasis-enthesitis-enterocolitis-dactylitis-uveitis-peripheral synovitis (SPEED-UP) spectrum disease. The aim is to review the new targeted pharmacological treatment options for all these diseases. All biological or targeted synthetic drugs with U.S. Food and Drug Administration (FDA) or European Medicines Agency (EMA) approval for any of the diagnoses axSpA, PsA, psoriasis, IBD, or non-infectious uveitis were included. Some of the drugs have documented efficacy in more than one of the diseases, e.g. tumor necrosis factor (TNF) inhibitors. However, other drugs are particularly effective for a specific inflamed tissue and approved in only one or two of the disease entities, e.g. abatacept for peripheral arthritis and vedolizumab for inflammatory bowel disease. This contributes with bedside to bench understanding of the immunology underlying this disease spectrum and provides clinicians with an overview that can assist stratified treatment decisions. We hope that this review will help guide clinicians to speed up treatment of patients with this disease spectrum. (Copyright © 2020. Published by Elsevier B.V.) |
| فهرسة مساهمة: | Keywords: Autoimmunity; Crohn's disease; Dactylitis; Enterocolitis; Enthesitis; Immune mediated inflammatory disease; Inflammatory bowel disease; Noninfectious uveitis; Peripheral synovitis; Psoriasis; Psoriatic arthritis; Spondylitis; Spondyloarthritis; Ulcerative colitis; Uveitis |
| تواريخ الأحداث: | Date Created: 20201216 Date Completed: 20210215 Latest Revision: 20210215 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.autrev.2020.102731 |
| PMID: | 33326852 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1873-0183 |
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| DOI: | 10.1016/j.autrev.2020.102731 |