دورية أكاديمية
Helical water-soluble Ni II complexes with pyridoxal ligand derivatives: Structural evaluation and interaction with biomacromolecules.
| العنوان: | Helical water-soluble Ni II complexes with pyridoxal ligand derivatives: Structural evaluation and interaction with biomacromolecules. |
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| المؤلفون: | Mainardi Martins F; Laboratório de Materiais Inorgânicos, Departamento de Química, CCNE, UFSM, Santa Maria, RS, Brazil., Chaves OA; Instituto SENAI de Inovação em Química Verde, Firjan-SENAI, Rio de Janeiro, RJ, Brazil., Acunha TV; Laboratório de Bioinorgânica e Materiais Porfirínicos, Departamento de Química, CCNE, UFSM, Santa Maria, RS, Brazil., Roman D; Laboratório de Síntese e Modificação Molecular, Faculdade de Ciências Exatas e Tecnologia, UFGD, Dourados, MS, Brazil., Iglesias BA; Laboratório de Bioinorgânica e Materiais Porfirínicos, Departamento de Química, CCNE, UFSM, Santa Maria, RS, Brazil., Back DF; Laboratório de Materiais Inorgânicos, Departamento de Química, CCNE, UFSM, Santa Maria, RS, Brazil. Electronic address: daviback@gmail.com. |
| المصدر: | Journal of inorganic biochemistry [J Inorg Biochem] 2021 Feb; Vol. 215, pp. 111307. Date of Electronic Publication: 2020 Nov 26. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, Elsevier. |
| مواضيع طبية MeSH: | Coordination Complexes/*chemistry , Nickel/*chemistry , Pyridoxal/*chemistry, Adipates/chemistry ; Azo Compounds/chemistry ; Crystallography, X-Ray/methods ; DNA/chemistry ; Humans ; Hydrazines/chemistry ; Ligands ; Molecular Docking Simulation/methods ; Molecular Structure ; Schiff Bases/chemistry ; Serum Albumin, Human/chemistry ; Solubility ; Succinates/chemistry ; Thiosemicarbazones/chemistry ; Water/chemistry ; X-Ray Diffraction/methods |
| مستخلص: | This article deals with the synthesis of Schiff-based bis-azomethine-based ligands derived from pyridoxal and aliphatic dihydrazides and the synthesis of nickel(II) complexes C1-C4. The synthesized complexes had their structures elucidated by monocrystal X-ray diffraction and were characterized by vibrational and absorption spectroscopy. The synthesized ligands have characteristics that allow the formation of self-assembly processes, thus, the flexibility or rigidity of the coordination of organic molecules added to the orbitals of the Ni II cation leads to the formation of helical complexes with double helix and a dinucler nickel(II) complex. Moreover, compounds was their interactions with CT-DNA and HSA absorption and emission analysis and molecular docking calculations. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: DNA-binding; Helicates; Nickel(II) complexes; Protein-binding; Pyridoxal |
| المشرفين على المادة: | 0 (Adipates) 0 (Azo Compounds) 0 (Coordination Complexes) 0 (Hydrazines) 0 (Ligands) 0 (Schiff Bases) 0 (Succinates) 0 (Thiosemicarbazones) 0 (azomethine) 059QF0KO0R (Water) 3THM379K8A (Pyridoxal) 4146-43-4 (succinic dihydrazide) 7OV03QG267 (Nickel) 9007-49-2 (DNA) VK98I9YW5M (adipic dihydrazide) W8V7FYY4WH (carbohydrazide) ZIF514RVZR (Serum Albumin, Human) |
| تواريخ الأحداث: | Date Created: 20201220 Date Completed: 20210907 Latest Revision: 20210907 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.jinorgbio.2020.111307 |
| PMID: | 33341589 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3344 |
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| DOI: | 10.1016/j.jinorgbio.2020.111307 |