دورية أكاديمية
Prognostic value of electrocardiographic abnormalities in adults from the Brazilian longitudinal study of adults' health.
| العنوان: | Prognostic value of electrocardiographic abnormalities in adults from the Brazilian longitudinal study of adults' health. |
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| المؤلفون: | Pinto-Filho MM; Cardiology, Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Brant LC; Internal Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Dos Reis RP; Statistics, UFRGS, Porto Alegre, RS, Brazil., Giatti L; Medicina Preventiva e Social, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Duncan BB; Faculdade de Medicina da UFRGS, Porto Alegre, RS, Brazil., Lotufo PA; Center for Clinical and Epidemiologic Research, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil., da Fonseca MJM; Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, RJ, Brazil., Mill JG; Physiological Sciences, Federal University of Espírito Santo, VITÓRIA, ESPÍRITO SANTO, Brazil., de Almeida MDCC; Fiocruz Bahia, Salvador, BA, Brazil., MacFarlane P; Inst CAMS, University of Glasgow, Glasgow, UK., Barreto SM; Social and Preventive Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Ribeiro ALP; Internal Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil tom1963br@yahoo.com.br. |
| المصدر: | Heart (British Cardiac Society) [Heart] 2021 Oct; Vol. 107 (19), pp. 1560-1566. Date of Electronic Publication: 2020 Dec 23. |
| نوع المنشور: | Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9602087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-201X (Electronic) Linking ISSN: 13556037 NLM ISO Abbreviation: Heart Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Pub. Group, c1996- |
| مواضيع طبية MeSH: | Health Status*, Cardiovascular Diseases/*epidemiology , Electrocardiography/*methods , Primary Health Care/*methods , Risk Assessment/*methods, Adult ; Aged ; Brazil/epidemiology ; Cardiovascular Diseases/physiopathology ; Female ; Follow-Up Studies ; Humans ; Incidence ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Risk Factors ; Survival Rate/trends |
| مستخلص: | Objective: Cardiovascular diseases (CVDs) are highly preventable non-communicable diseases. ECG is a potential tool for risk stratification with respect to CVD. Our aim was to evaluate ECG's role in all-cause and cardiovascular mortality prediction. Methods: Participants from the Brazilian Longitudinal Study of Adult Health, free of known CVD at baseline were included. A 12-lead ECG was obtained at baseline (2008-2010). Participants were followed up to 2018 by annual interviews. Deaths were independently reviewed. Cox as well as Fine and Grey multivariable regression models were applied to evaluate if the presence of any major electrocardiographic abnormality (MEA), defined according to the Minnesota Code system, would predict total and cardiovascular deaths. We also evaluated the Net Reclassification Index of adding MEA to the Systematic Coronary Risk Evaluation (SCORE). Results: The 13 428 participants (median age 51 years, 45% men) were followed up for 8±1 years. All-cause and cardiovascular mortality occurred in 2.8% and 1.2% of the population, respectively. Prevalent MEA was an independent predictor of overall (HR=2.3, 95% CI 1.7 to 2.9) and cardiovascular mortality (HR=4.6, 95% CI 3.0 to 7.0) after adjustments for age, race, education and traditional cardiovascular risk factors. Adding MEA to the SCORE resulted in 9% mis-reclassification in the non-event subgroup and 33% correct reclassification in those with a fatal cardiovascular event. Conclusion: Presence of MEA was an independent predictor of overall and cardiovascular mortality. ECG may have a role in risk prediction of cardiovascular mortality in primary care. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.) |
| فهرسة مساهمة: | Keywords: ECG/electrocardiogram; cardiac risk factors and prevention |
| تواريخ الأحداث: | Date Created: 20201228 Date Completed: 20211208 Latest Revision: 20211214 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1136/heartjnl-2020-318097 |
| PMID: | 33361354 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1468-201X |
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| DOI: | 10.1136/heartjnl-2020-318097 |