دورية أكاديمية
SARS-Cov-2 infection in transplant-related biology: Where do we stand?
| العنوان: | SARS-Cov-2 infection in transplant-related biology: Where do we stand? |
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| المؤلفون: | Kong D; Department of Surgery, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland)., Li M; Physical Examination Center, Tianjin First Central Hospital, Tianjin, China (mainland)., Gong W; Department of Surgery, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland). |
| المصدر: | Annals of transplantation [Ann Transplant] 2020 Dec 29; Vol. 25, pp. e924768. Date of Electronic Publication: 2020 Dec 29. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: International Scientific Literature, Inc Country of Publication: United States NLM ID: 9802544 Publication Model: Electronic Cited Medium: Internet ISSN: 2329-0358 (Electronic) Linking ISSN: 14259524 NLM ISO Abbreviation: Ann Transplant Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2013- > : Smithtown, New York: International Scientific Literature, Inc. Original Publication: Warsaw : Polish Transplantology Foundation : Transplantation Institute, Warsaw Medical School, 1996- |
| مواضيع طبية MeSH: | Transplant Recipients*, COVID-19/*virology, Humans ; Organ Transplantation ; Risk Factors |
| مستخلص: | Since December 2019, the novel coronavirus (SARS-CoV-2) emerged in Wuhan and rapidly spread throughout the world. There are nearly 3 951 905 confirmed cases of novel coronary pneumonia and more than 275 067 deaths worldwide, [JHU data-09/05/2020, https://www.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6]. A great number of patients contracted SARS-Cov-2 pneumonia (COVID-19). SARS-CoV-2 invades human target cells through receptor angiotensin-converting enzyme II (ACE2), which are expressed in the lung, kidney, and ileum and mediate inflammatory responses and immune activities. High plasma levels of proinflammatory cytokines were detected in the infected patients. These factors may predispose transplant patients to high risk of poor outcomes. Therefore, transplant patients might be affected by this coronavirus infection and protection of allografts should receive special attention during this outbreak. In the present study we attempt to delineate the transplant-related biology of SARS-CoV-2 infection. |
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| تواريخ الأحداث: | Date Created: 20201229 Date Completed: 20210114 Latest Revision: 20210114 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC7777149 |
| DOI: | 10.12659/AOT.924768 |
| PMID: | 33372171 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2329-0358 |
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| DOI: | 10.12659/AOT.924768 |