دورية أكاديمية

Impact of an Oral Nutritional Protocol with Oligomeric Enteral Nutrition on the Quality of Life of Patients with Oncology Treatment-Related Diarrhea.

التفاصيل البيبلوغرافية
العنوان: Impact of an Oral Nutritional Protocol with Oligomeric Enteral Nutrition on the Quality of Life of Patients with Oncology Treatment-Related Diarrhea.
المؤلفون: Sanz-Paris A; Department of Endocrinology and Nutrition, Miguel Servet Hospital, 50009 Zaragoza, Spain.; Instituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain., Martinez-Trufero J; Department of Medical Oncology, Miguel Servet Hospital, 50009 Zaragoza, Spain., Lambea-Sorrosal J; Department of Oncology, University Clinic Hospital, 50009 Zaragoza, Spain., Milà-Villarroel R; Group Research on Wellbeing (GRoW), Blanquerna School of Health Sciences-Universitat Ramon Llull, 08025 Barcelona, Spain., Calvo-Gracia F; Department of Endocrinology and Nutrition, University Clinic Hospital, 50009 Zaragoza, Spain., On Behalf Of The Diapoeno Study
المصدر: Nutrients [Nutrients] 2020 Dec 29; Vol. 13 (1). Date of Electronic Publication: 2020 Dec 29.
نوع المنشور: Journal Article; Multicenter Study; Observational Study
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Nutritional Status* , Quality of Life*, Diarrhea/*diet therapy , Enteral Nutrition/*methods , Medical Oncology/*methods, Aged ; Aged, 80 and over ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Neoplasms ; Prospective Studies ; Severity of Illness Index
مستخلص: (1) Background: Nutritional status can influence the quality of life (QoL) of cancer patients. (2) Methods: This subanalysis evaluated the impact of an oral oligomeric enteral nutrition (OEN) protocol on the QoL of patients with oncology treatment-related diarrhea (OTRD) in a multicenter, observational, prospective study (DIAPOENO study). QoL was assessed with the Nottingham Health Profile (NHP) at baseline and after eight weeks of OEN treatment. (3) In the overall population, all the NHP categories significantly improved after eight weeks of OEN treatment: energy levels ( p < 0.001), pain ( p < 0.001), emotional reactions ( p < 0.001), sleep ( p < 0.001), social isolation ( p = 0.023), and physical abilities ( p = 0.001). QoL improvement was higher in patients with improved or maintained nutritional status and in those with improved consistency of stools with the OEN protocol. However, QoL did not significantly improve in patients with worse nutritional status and with worse or maintained stool consistency with the OEN protocol. QoL improved regardless of disease severity. Multivariate logistic regression analysis showed that weight change was significantly associated with improved QoL (OR 2.90-5.3), except for social isolation, in models unadjusted and adjusted to age, sex, oncology treatment, and stool consistency. (4) Conclusion: In this subanalysis, the OEN protocol was associated with improved QoL.
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معلومات مُعتمدة: 2541 Fundacion Miguel Servet
فهرسة مساهمة: Keywords: nutritional protocol; oligomeric enteral nutrition; oncology treatment-related diarrhea; quality of life
تواريخ الأحداث: Date Created: 20210101 Date Completed: 20210503 Latest Revision: 20230919
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC7824279
DOI: 10.3390/nu13010084
PMID: 33383949
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu13010084