دورية أكاديمية
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The fentanyl phase of the opioid epidemic in Cuyahoga County, Ohio, United States.

التفاصيل البيبلوغرافية
العنوان: The fentanyl phase of the opioid epidemic in Cuyahoga County, Ohio, United States.
المؤلفون: Deo VS; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Gilson TP; Chief Medical Examiner and Executive Director of Regional Forensic Science Laboratory, Cuyahoga County, OH, USA.; Cuyahoga County Medical Examiner's Office, Cleveland, OH, USA., Kaspar C; Cuyahoga County Medical Examiner's Office, Cleveland, OH, USA., Singer ME; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
المصدر: Journal of forensic sciences [J Forensic Sci] 2021 May; Vol. 66 (3), pp. 926-933. Date of Electronic Publication: 2021 Jan 04.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Pub Country of Publication: United States NLM ID: 0375370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-4029 (Electronic) Linking ISSN: 00221198 NLM ISO Abbreviation: J Forensic Sci Subsets: MEDLINE
أسماء مطبوعة: Publication: 2006- : Malden, MA : Blackwell Pub.
Original Publication: [Chicago, Ill.] : Callaghan and Co., 1956-
مواضيع طبية MeSH: Drug Overdose/*mortality , Fentanyl/*poisoning , Illicit Drugs/*poisoning , Opioid-Related Disorders/*mortality, Adult ; Age Distribution ; Coroners and Medical Examiners ; Drug Overdose/drug therapy ; Drug Prescriptions/statistics & numerical data ; Female ; Heroin/poisoning ; Humans ; Male ; Middle Aged ; Naloxone/administration & dosage ; Narcotic Antagonists/administration & dosage ; Ohio/epidemiology ; Racial Groups/statistics & numerical data ; Sex Distribution
مستخلص: Since late 2014, fentanyl has become the major driver of opioid mortality in the United States. However, a descriptive analysis of fentanyl victims is limited. We studied the 2016 fentanyl and heroin overdose deaths and compared them to previously studied heroin-associated fatalities from 2012 over a wide range of demographic and investigative variables, including overdose scene findings, toxicology results, and prescription drug history. We observed a significant increase in fentanyl-related deaths (n = 421, 2016) versus heroin deaths (n = 160, 2012) but the baseline demographics between both cohorts remained similar. Victims were predominantly of ages 35-64 years (60%-64%), White (83%-85%), and male (73%-76%). 2016 fentanyl decedents were more likely to have naloxone administered upon overdose, and the majority still had a positive prescription history for a controlled substance. Toxicology data showed a decrease in mean morphine and 6-monoacetylmorphine concentrations when cointoxication with fentanyl occurred. Our study emphasizes the medical examiner's role as a public health data source and bridge between different stakeholders combating the opioid epidemic.
(© 2021 American Academy of Forensic Sciences.)
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فهرسة مساهمة: Keywords: Ohio; United States; autopsy; fentanyl; forensic pathology; forensic toxicology; heroin; mortality; opioid; overdose; prescription data
المشرفين على المادة: 0 (Illicit Drugs)
0 (Narcotic Antagonists)
36B82AMQ7N (Naloxone)
70D95007SX (Heroin)
UF599785JZ (Fentanyl)
تواريخ الأحداث: Date Created: 20210104 Date Completed: 20210629 Latest Revision: 20211204
رمز التحديث: 20240628
DOI: 10.1111/1556-4029.14665
PMID: 33394503
قاعدة البيانات: MEDLINE
الوصف
تدمد:1556-4029
DOI:10.1111/1556-4029.14665