دورية أكاديمية
Radioactive Iodine Following Total Thyroidectomy Is Comparable to Lobectomy in Low/Intermediate-Risk Differentiated Thyroid Carcinoma: A Meta-Analysis.
العنوان: | Radioactive Iodine Following Total Thyroidectomy Is Comparable to Lobectomy in Low/Intermediate-Risk Differentiated Thyroid Carcinoma: A Meta-Analysis. |
---|---|
المؤلفون: | Altedlawi Albalawi IA 2nd; Surgical Oncology, University of Tabuk, Tabuk, SAU., Altidlawi AI; Surgery, University of Tabuk, Tabuk, SAU., Mirghani H; Internal Medicine, University of Tabuk, Tabuk, SAU. |
المصدر: | Cureus [Cureus] 2020 Dec 28; Vol. 12 (12), pp. e12332. Date of Electronic Publication: 2020 Dec 28. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: Electronic Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Palo Alto, CA : Cureus, Inc. |
مستخلص: | Radioactive iodine (RAI) is being increasingly used for remnants ablation of low/intermediate-risk differentiated thyroid carcinoma (DTC). Importantly, total thyroidectomy (TT) is in common use in the treatment of low-grade DTC to facilitate RAI despite the recommendations for lobectomy. Intermediate-risk DTC has been an arena of controversy (fueled by weighing the risks and benefits of RAI). This meta-analysis aimed to assess the role of RAI following TT in comparison to lobectomy in low/intermediate-risk patients with DTC. We identified 482 references through PubMed, Cochrane Library, EBSCO, and Google Scholar databases. The keywords used were "differentiated thyroid carcinoma", "low/intermediate risk", "radioactive iodine following total thyroidectomy", "total thyroidectomy versus lobectomy and RAI", "remnants ablation", "recurrence", "survival rate", "tumor-specific cancer death", "overall mortality", and "tumor-specific mortality". From the 67 full texts screened, only seven studies fulfilled the inclusion and exclusion criteria. The studies were from the USA, Australia, Asia, Mexico, and South America (63,268 patients included; five were retrospective and two prospective cohorts). No differences were found regarding recurrence and survival rate between TT followed by RAI and lobectomy alone. However, the current data were limited by the observational studies included, the pooling of both recurrence and survival rate, and the significant heterogeneity observed. The ongoing randomized controlled trials are awaited to resolve the issue. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2020, Altedlawi Albalawi et al.) |
References: | Thyroid. 2007 Dec;17(12):1235-42. (PMID: 17988197) Hell J Nucl Med. 2017 Jan-Apr;20(1):3-10. (PMID: 28315902) Endocr Relat Cancer. 2016 May;23(5):367-76. (PMID: 26917553) Thyroid. 2010 Nov;20(11):1235-45. (PMID: 21062195) J Clin Endocrinol Metab. 1948 Jun;8(6):423-32. (PMID: 18871464) Arch Endocrinol Metab. 2018 Apr 05;62(2):149-156. (PMID: 29641738) Am J Clin Oncol. 1998 Feb;21(1):77-81. (PMID: 9499265) J Clin Endocrinol Metab. 2004 Aug;89(8):3668-76. (PMID: 15292285) Clin Nucl Med. 2010 Jun;35(6):396-9. (PMID: 20479583) Am J Med. 1981 Mar;70(3):511-8. (PMID: 7211893) J Clin Endocrinol Metab. 2016 Jul;101(7):2692-700. (PMID: 27023446) World J Surg. 2002 Aug;26(8):879-85. (PMID: 12016468) J Surg Res. 2019 Nov;243:189-197. (PMID: 31185435) PLoS One. 2020 Jun 15;15(6):e0234843. (PMID: 32542018) Cir Cir. 2011 Mar-Apr;79(2):118-25. (PMID: 21631972) Nucl Med Commun. 2011 Oct;32(10):954-9. (PMID: 21849927) J Nucl Med. 2018 Aug;59(8):1187-1194. (PMID: 29653980) J Clin Endocrinol Metab. 2015 Apr;100(4):1529-36. (PMID: 25642591) Asian Pac J Cancer Prev. 2013;14(11):6209-13. (PMID: 24377506) Clin Endocrinol (Oxf). 2019 Aug;91(2):331-339. (PMID: 30525210) J Evid Based Med. 2015 Feb;8(1):2-10. (PMID: 25594108) Thyroid. 2017 Feb;27(2):174-181. (PMID: 27750028) |
فهرسة مساهمة: | Keywords: differentiated thyroid carcinoma; lobectomy; radioactive iodine; remnants ablation; total thyroidectomy |
تواريخ الأحداث: | Date Created: 20210106 Latest Revision: 20210111 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC7773301 |
DOI: | 10.7759/cureus.12332 |
PMID: | 33403191 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2168-8184 |
---|---|
DOI: | 10.7759/cureus.12332 |