دورية أكاديمية
أعرض في EDS

The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression.

التفاصيل البيبلوغرافية
العنوان: The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression.
المؤلفون: Kaya-Çopur A; Aix Marseille University, CNRS, IBDM, Turing Center for Living Systems, Marseille, France.; Max Planck Institute of Biochemistry, Martinsried, Germany., Marchiano F; Aix Marseille University, CNRS, IBDM, Turing Center for Living Systems, Marseille, France., Hein MY; Max Planck Institute of Biochemistry, Martinsried, Germany., Alpern D; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Russeil J; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Luis NM; Aix Marseille University, CNRS, IBDM, Turing Center for Living Systems, Marseille, France., Mann M; Max Planck Institute of Biochemistry, Martinsried, Germany., Deplancke B; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Habermann BH; Aix Marseille University, CNRS, IBDM, Turing Center for Living Systems, Marseille, France., Schnorrer F; Aix Marseille University, CNRS, IBDM, Turing Center for Living Systems, Marseille, France.; Max Planck Institute of Biochemistry, Martinsried, Germany.
المصدر: ELife [Elife] 2021 Jan 06; Vol. 10. Date of Electronic Publication: 2021 Jan 06.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Cambridge, UK : eLife Sciences Publications, Ltd., 2012-
مواضيع طبية MeSH: Gene Expression Regulation*, Drosophila melanogaster/*physiology , Hippo Signaling Pathway/*physiology , Muscle Fibers, Skeletal/*physiology , Myofibrils/*metabolism , Sarcomeres/*genetics, Animals ; Drosophila melanogaster/genetics
مستخلص: Skeletal muscles are composed of gigantic cells called muscle fibers, packed with force-producing myofibrils. During development, the size of individual muscle fibers must dramatically enlarge to match with skeletal growth. How muscle growth is coordinated with growth of the contractile apparatus is not understood. Here, we use the large Drosophila flight muscles to mechanistically decipher how muscle fiber growth is controlled. We find that regulated activity of core members of the Hippo pathway is required to support flight muscle growth. Interestingly, we identify Dlg5 and Slmap as regulators of the STRIPAK phosphatase, which negatively regulates Hippo to enable post-mitotic muscle growth. Mechanistically, we show that the Hippo pathway controls timing and levels of sarcomeric gene expression during development and thus regulates the key components that physically mediate muscle growth. Since Dlg5, STRIPAK and the Hippo pathway are conserved a similar mechanism may contribute to muscle or cardiomyocyte growth in humans.
Competing Interests: AK, FM, MH, DA, JR, NL, MM, BD, BH, FS No competing interests declared
(© 2021, Kaya-Çopur et al.)
References: Dev Cell. 2010 Oct 19;19(4):491-505. (PMID: 20951342)
J Cell Sci. 2020 May 26;133(10):. (PMID: 32184260)
Mol Cell. 2010 Aug 27;39(4):521-34. (PMID: 20797625)
Nat Cell Biol. 2006 Jan;8(1):27-36. (PMID: 16341207)
Nature. 2008 Aug 7;454(7205):784-8. (PMID: 18600262)
Nat Cell Biol. 2003 Oct;5(10):914-20. (PMID: 14502294)
Elife. 2017 Oct 24;6:. (PMID: 29063833)
Elife. 2014 Aug 18;3:. (PMID: 25135939)
Nat Rev Cancer. 2007 Mar;7(3):182-91. (PMID: 17318211)
Elife. 2016 Feb 20;5:e12068. (PMID: 26896675)
Cell. 2015 Oct 22;163(3):712-23. (PMID: 26496610)
Sci Signal. 2014 Aug 05;7(337):re4. (PMID: 25097035)
J Exp Biol. 2008 Jul;211(Pt 13):2005-13. (PMID: 18552289)
Skelet Muscle. 2015 Jul 15;5:22. (PMID: 26180627)
Dev Biol. 2010 Jan 15;337(2):303-12. (PMID: 19900439)
Cell. 2013 Sep 12;154(6):1342-55. (PMID: 24012335)
J Cell Biol. 1998 Jun 1;141(5):1135-45. (PMID: 9606206)
Cell Rep. 2017 Dec 19;21(12):3612-3623. (PMID: 29262338)
Nucleic Acids Res. 2019 Jul 2;47(W1):W183-W190. (PMID: 31069376)
Nature. 2007 Jul 12;448(7150):151-6. (PMID: 17625558)
Spine (Phila Pa 1976). 2011 Dec 15;36(26):E1666-74. (PMID: 21415810)
Cell. 2014 Jul 3;158(1):143-156. (PMID: 24995985)
Int J Biochem Cell Biol. 2014 Feb;47:118-48. (PMID: 24333164)
Mech Dev. 2017 Apr;144(Pt A):92-101. (PMID: 27913119)
FEBS J. 2013 Sep;280(17):4294-314. (PMID: 23517348)
Development. 1991 Sep;113(1):79-89. (PMID: 1765010)
Genome Biol. 2014;15(12):550. (PMID: 25516281)
FEBS J. 2018 Oct;285(20):3688-3694. (PMID: 29761627)
Front Cell Dev Biol. 2020 Mar 19;8:161. (PMID: 32266255)
Curr Biol. 2014 Mar 31;24(7):705-16. (PMID: 24631244)
Development. 2011 Sep;138(18):3907-14. (PMID: 21831922)
Curr Biol. 2014 Mar 31;24(7):793-800. (PMID: 24656828)
Development. 2011 Jun;138(11):2337-46. (PMID: 21525075)
J Mol Biol. 2015 Jun 19;427(12):2151-8. (PMID: 25868382)
Nature. 2011 Jun 08;474(7350):179-83. (PMID: 21654799)
PLoS Biol. 2019 Mar 27;17(3):e3000057. (PMID: 30917109)
Handb Exp Pharmacol. 2017;235:39-75. (PMID: 27832381)
Elife. 2016 Oct 12;5:. (PMID: 27731794)
Nat Biotechnol. 2008 Dec;26(12):1367-72. (PMID: 19029910)
EMBO J. 2015 Apr 1;34(7):940-54. (PMID: 25712476)
Elife. 2019 Oct 02;8:. (PMID: 31577228)
Dev Cell. 2004 Jul;7(1):9-20. (PMID: 15239950)
Genes Dev. 2016 Dec 15;30(24):2696-2709. (PMID: 28087714)
Genes Dev. 1997 Oct 1;11(19):2510-21. (PMID: 9334316)
Nat Methods. 2012 Jun 28;9(7):676-82. (PMID: 22743772)
Methods Mol Biol. 2016;1418:93-110. (PMID: 27008011)
Dev Biol. 2012 Jan 15;361(2):191-207. (PMID: 22008792)
BMC Biol. 2013 Feb 01;11:12. (PMID: 23374633)
Cell. 2015 Jan 15;160(1-2):313-23. (PMID: 25557078)
Nat Methods. 2011 May;8(5):405-7. (PMID: 21460824)
Elife. 2018 May 30;7:. (PMID: 29846170)
Cell. 2007 Sep 21;130(6):1120-33. (PMID: 17889654)
J Biol Chem. 1996 Apr 5;271(14):8266-74. (PMID: 8626521)
Development. 2018 Mar 8;145(5):. (PMID: 29440303)
Adv Exp Med Biol. 2008;642:176-91. (PMID: 19181101)
Nat Commun. 2015 Jan 12;6:6048. (PMID: 25581281)
Science. 1991 Nov 29;254(5036):1388-90. (PMID: 1962198)
Dev Cell. 2008 Mar;14(3):377-87. (PMID: 18258485)
Elife. 2019 Oct 29;8:. (PMID: 31661072)
Nature. 2011 Nov 16;479(7373):406-9. (PMID: 22094701)
Cell. 2003 Aug 22;114(4):445-56. (PMID: 12941273)
Dev Cell. 2008 Mar;14(3):388-98. (PMID: 18258486)
EMBO Rep. 2015 Feb;16(2):178-91. (PMID: 25532219)
Bioinformatics. 2011 Sep 1;27(17):2453-4. (PMID: 21727141)
Science. 2003 Dec 5;302(5651):1765-8. (PMID: 14657498)
Development. 2017 Apr 1;144(7):1261-1272. (PMID: 28174246)
Development. 2008 Mar;135(6):1081-8. (PMID: 18256197)
Bioinformatics. 2013 Jan 1;29(1):15-21. (PMID: 23104886)
Genome Biol. 2019 Apr 19;20(1):71. (PMID: 30999927)
J Biol Chem. 2013 Feb 8;288(6):3977-88. (PMID: 23275380)
Elife. 2019 Nov 20;8:. (PMID: 31746737)
Development. 1991 Sep;113(1):67-77. (PMID: 1765009)
PLoS One. 2013;8(3):e59622. (PMID: 23544078)
Cell. 2005 Aug 12;122(3):421-34. (PMID: 16096061)
Mol Cell Proteomics. 2014 Sep;13(9):2513-26. (PMID: 24942700)
Elife. 2021 Jan 06;10:. (PMID: 33404503)
Development. 2004 Aug;131(15):3761-72. (PMID: 15262890)
BMC Biotechnol. 2013 Feb 14;13:12. (PMID: 23410102)
Nucleic Acids Res. 2016 Jul 8;44(W1):W90-7. (PMID: 27141961)
Curr Biol. 2008 Mar 25;18(6):435-41. (PMID: 18313299)
Curr Biol. 2006 Dec 19;16(24):2459-65. (PMID: 17174922)
EMBO J. 2011 May 10;30(12):2325-35. (PMID: 21556047)
Adv Exp Med Biol. 2008;642:1-14. (PMID: 19181089)
Nat Commun. 2021 Apr 7;12(1):2091. (PMID: 33828099)
Dev Cell. 2018 Aug 6;46(3):271-284.e5. (PMID: 30032991)
Nature. 2010 Mar 11;464(7286):287-91. (PMID: 20220848)
Cell Res. 2015 Dec;25(12):1299-313. (PMID: 26611634)
Development. 2019 Jun 28;146(13):. (PMID: 31164352)
J Cell Biol. 2017 Feb;216(2):441-461. (PMID: 28100687)
J Biol Chem. 1992 Aug 25;267(24):17234-40. (PMID: 1324927)
PLoS Biol. 2018 Apr 27;16(4):e2004718. (PMID: 29702642)
Elife. 2015 Mar 31;4:e06567. (PMID: 25826608)
Genes Dev. 2001 Nov 15;15(22):2967-79. (PMID: 11711432)
Methods. 2014 Jun 15;68(1):2-14. (PMID: 24625467)
J Cell Sci. 2013 Jan 1;126(Pt 1):139-48. (PMID: 23178940)
Nat Rev Cancer. 2019 Aug;19(8):454-464. (PMID: 31270418)
Nat Commun. 2020 Jul 24;11(1):3722. (PMID: 32709902)
Dev Biol. 1993 Dec;160(2):443-65. (PMID: 8253277)
Am J Physiol. 1996 Jun;270(6 Pt 1):C1624-33. (PMID: 8764144)
J Cell Biol. 2010 May 17;189(4):739-54. (PMID: 20479470)
Nat Rev Mol Cell Biol. 2009 Apr;10(4):293-8. (PMID: 19190670)
Genetics. 2007 Mar;175(3):1505-31. (PMID: 17194782)
Curr Opin Genet Dev. 2015 Jun;32:162-70. (PMID: 25989064)
معلومات مُعتمدة: P40 OD018537 United States OD NIH HHS
فهرسة مساهمة: Keywords: D. melanogaster; Drosophila; Hippo; developmental biology; muscle; myofibril; sarcomere; yorkie
سلسلة جزيئية: GEO GSE158957
تواريخ الأحداث: Date Created: 20210106 Date Completed: 20220217 Latest Revision: 20240330
رمز التحديث: 20240330
مُعرف محوري في PubMed: PMC7815313
DOI: 10.7554/eLife.63726
PMID: 33404503
قاعدة البيانات: MEDLINE
الوصف
تدمد:2050-084X
DOI:10.7554/eLife.63726