دورية أكاديمية
Transaminase profile and hepatic histopathological traits in Piaractus mesopotamicus exposed to insecticide Diflubenzuron.
| العنوان: | Transaminase profile and hepatic histopathological traits in Piaractus mesopotamicus exposed to insecticide Diflubenzuron. |
|---|---|
| المؤلفون: | Silva ALN; Programa de Pós Graduação em Ciência Animal, Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil., Rodrigues RA; Departamento de Aquicultura do Centro de Ciências Agrárias, Universidade Federal de Santa Catarina, Florianópolis, Brazil., Siqueira MS; Laboratório de Patologia Experimental (LAPEx), Instituto de Biociências Instituto de Biociências, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil., Farias KNN; Programa de Pós Graduação em Ciência Animal, Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil., Kuibida KV; Laboratório de Patologia Experimental (LAPEx), Instituto de Biociências Instituto de Biociências, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil., Franco-Belussi L; Laboratório de Patologia Experimental (LAPEx), Instituto de Biociências Instituto de Biociências, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil., Fernandes CE; Laboratório de Patologia Experimental (LAPEx), Instituto de Biociências Instituto de Biociências, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil. carlos.fernandes@ufms.br. |
| المصدر: | Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 May; Vol. 28 (17), pp. 22002-22010. Date of Electronic Publication: 2021 Jan 07. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: Germany NLM ID: 9441769 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1614-7499 (Electronic) Linking ISSN: 09441344 NLM ISO Abbreviation: Environ Sci Pollut Res Int Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2013->: Berlin : Springer Original Publication: Landsberg, Germany : Ecomed |
| مواضيع طبية MeSH: | Characiformes* , Diflubenzuron* , Insecticides*, Alanine Transaminase ; Animals ; Brazil ; Liver |
| مستخلص: | Diflubenzuron (DFB) is a widely used insecticide to control ectoparasites in fish farming. Although therapeutic concentrations (i.e., 50 to 100 mg/L) are safe as they fail to induce mortality, they can promote tissue changes. In Brazil, Pacu (Piaractus mesopotamicus) is a native species used for commercial production, and it remains crucial to determine underlying mechanisms to mitigate the potential effects of pathogens on productivity. The aim of this study was to analyze the transaminase profile and histopathological changes in the liver of P. mesopotamicus exposed to a DFB bath. Hence, the fish were exposed to an immersion bath containing a 70 mg/L nominal concentration of Difluchem 240 SC® (24% (m/m) DFB) for 30 (n = 10), 60 (n = 10), and 120 min (n = 10), every 24 h for 3 days. Following exposure, plasma transaminases and liver histology were analyzed. In DFB-exposed fish, levels of aspartate transaminase (AST) and alanine transaminase (ALT) were elevated when compared with the control at 30 and 60 min. Furthermore, liver morphology was altered based on exposure times. Compared with controls, the degree of reversible damage (degree of tissue change (DTC)) demonstrated high scores for all exposure times, with no difference between individual groups. Irreversible changes were increased in the 60 and 120-min baths. These findings highlight the impact of the therapeutic DFB concentration (i.e., 70 mg/L), revealing that 60-min and 120-min bathing induces irreversible and progressive hepatic changes. |
| References: | Ardeshir RA, Zolgharnein H, Movahedinia A, Salamat N, Zabihi E (2017) Comparison of waterborne and intraperitoneal exposure to fipronil in the Caspian white fish (Rutilus frisii) on acute toxicity and histopathology. Toxicol Rep 4:348–357. https://doi.org/10.1016/j.toxrep.2017.06.010. (PMID: 10.1016/j.toxrep.2017.06.010) Benze TP, Sakuragui MM, De Paula Zago LH, Fernandes MN (2016) Subchronic exposure to diflubenzuron causes health disorders in neotropical freshwater fish, Prochilodus lineatus. Environ Toxicol 31:533–542. https://doi.org/10.1002/tox.22065. (PMID: 10.1002/tox.22065) Bernet D, Schmidt H, Meier W, Burkhardt-Holm P, Wahli T (1999) Histopathology in fish: proposal for a protocol to assess aquatic pollution. J Fish Dis 22:25–34. https://doi.org/10.1046/j.1365-2761.1999.00134.x. (PMID: 10.1046/j.1365-2761.1999.00134.x) Branson EJ, Rønsberg SS, Ritchie G (2000) Efficacy of teflubenzuron (Calicide®) for the treatment of sea lice, lepeophtheirus salmonis (Krøyer 1838), infestations of farmed Atlantic salmon (Salmo salar L.). Aquac Res 31:861–867. https://doi.org/10.1046/j.1365-2109.2000.00509.x. (PMID: 10.1046/j.1365-2109.2000.00509.x) Brunk UT, Terman A (2002) Lipofuscin: mechanisms of age-related accumulation and influence on cell function. Free Radical Bio Med 33:611–619. https://doi.org/10.1016/S0891-5849(02)00959-0. (PMID: 10.1016/S0891-5849(02)00959-0) Camargo MM, Martinez CB (2007) Histopathology of gills, kidney and liver of a Neotropical fish caged in an urban stream. Neotrop Ichthyol 5:327–336. https://doi.org/10.1590/S1679-62252007000300013. (PMID: 10.1590/S1679-62252007000300013) Campbell PJ, Hammell KL, Dohoo IR, Ritchie G (2006a) Randomized clinical trial to investigate the effectiveness of teflubenzuron for treating sea lice on Atlantic salmon. Dis Aquat Org 70:101–108. https://doi.org/10.3354/dao070101. (PMID: 10.3354/dao070101) Campbell PJ, Hammell KL, Dohoo IR, Ritchie G (2006b) Historical control clinical trial to assess the effectiveness of teflubenzuron for treating sea lice on Atlantic salmon. Dis Aquat Org 70:109–114. https://doi.org/10.3354/dao070109. (PMID: 10.3354/dao070109) Carson FL, Hlakik C (2009) Histotechnology. A self-instructional text. 3nd ed, ASCP Press, Hong Kong. Cheville NF (2009) Ultrastructural pathology: the comparative cellular basis of disease. 2nd ed. Wiley-Blackwell A john Wiley of Sons, Inc. USA. Cunha MA (2017) Legislação de Fármacos utilizados na Aquicultura. In: Gomes LC, Heinzmann BM, Cunha MA (eds) Baldisserotto B. Farmacologia aplicada a aquicultura, Santa Maria, pp 19–20. Dabrowski K, Guderley H (2002) Intermediary metabolism. In: Halver JE, Hardy RW (eds) Fish nutrition. 3.ed. Washington, D.C., Academic Press, pp 309-365. Dane H, Sisman T (2015) Histopathological changes in gill and liver of Capoeta capoeta living in the Karasu River, Erzurum. Environ Toxicol 30:904–917. https://doi.org/10.1002/tox.21965. (PMID: 10.1002/tox.21965) Dantzger DD, Jonsson CM, Aoyama H (2018) Mixtures of diflubenzuron and p-chloroaniline changes the activities of enzymes biomarkers on tilapia fish (Oreochromis niloticus) in the presence and absence of soil. Ecotoxicol Environ Saf 148:367–376. https://doi.org/10.1016/j.ecoenv.2017.10.054. (PMID: 10.1016/j.ecoenv.2017.10.054) FAO (2018). World Food And Agriculture – Statistical Pocketbook 2018. Rome. 254 pp. Licence: CC BY-NC-SA 3.0 IGO. Fischer SA, Hall LW (1992) Environmental concentrations and aquatic toxicity data on diflubenzuron (Dimilin®). Crit Rev Toxicol 22:45–79. https://doi.org/10.3109/10408449209145321. (PMID: 10.3109/10408449209145321) Fossi MC, Leonzio C (1993) Nondestructive biomarkers in vertebrates. CRC Press. Grune T, Jung T, Merker K, Davies KJ (2004) Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and ‘aggresomes’ during oxidative stress, aging, and disease. Int J Biochem Cell Biol 36:2519–2530. https://doi.org/10.1016/j.biocel.2004.04.020. (PMID: 10.1016/j.biocel.2004.04.020) Heath AG (1995) Liver. In. Heath AG (ed) Water pollution and fish physiology. Second Edition. Lewis Publishers, USA, pp.125-139. Hinton DE, Segner H, Braunbeck T (2001) Toxic responses of the liver. In: Schlenk D, Benson WH (eds),Target organ toxicity in marine and freshwater teleosts. Volume 1: Organs, Taylor & Francis, Fl. USA, pp. 248-298. Hohn A, Jung T, Grimm S, Catalgol B, Weber D, Grune T (2011) Lipofuscin inhibits the proteasome by binding to surface motifs. Free Radical Bio Med 50:585–591. https://doi.org/10.1016/j.freeradbiomed.2010.12.011. (PMID: 10.1016/j.freeradbiomed.2010.12.011) Huggett RJ, Kimerle RA, Mehrle PM Jr, Bergan HL (1992) Biomarkers: biochemical, physiological, and histological markers of anthropogenic stress. Lewis Publishers, Boca Raton, p 347. Jomori K, Carneiro DJ, Martins IEG, Portella MC (2005) Economic evaluation of Piaractus mesopotamicus juvenile production in different rearing systems. Aquaculture 243:175–183. https://doi.org/10.1016/j.aquaculture.2004.09.034. (PMID: 10.1016/j.aquaculture.2004.09.034) Kildea MA, Allan GL, Kearney RE (2004) Accumulation and clearance of the anesthetics clove oil and AQUI-S TM from the edible tissue of silver perch (Bidyanus bidyanus). Aquaculture 232:265–277. https://doi.org/10.1016/S0044-8486(03)00483-6. (PMID: 10.1016/S0044-8486(03)00483-6) Kleiner DE (2018) Drugs and toxins. In: MacSween’s Pathology of the Liver. Ed 7, Elsevier, pp.673-779. Luvizotto-Santos R, Cordeiro PJM, Vieira EM (2009) Analysis of Diflubenzuron in tilapia filet by HPLC-DAD. J Chromatogr Sci 47:785–788. https://doi.org/10.1093/chromsci/47.9.785. (PMID: 10.1093/chromsci/47.9.785) Maduenho LP, Martinez CB (2008) Acute effects of diflubenzuron on the freshwater fish Prochilodus lineatus. Comp Biochem Physiol C148:265–272. https://doi.org/10.1016/j.cbpc.2008.06.010. (PMID: 10.1016/j.cbpc.2008.06.010) Marcon L, Bazzoli N, Honor Mounteer A, Anjos Benjamin LD (2015) Histological and histometric evaluation of the liver in Astyanax bimaculatus (Teleostei: Characidae), exposed to different concentrations of an organochlorine insecticide. Anat Rec 298:1754–1764. https://doi.org/10.1002/ar.23196. (PMID: 10.1002/ar.23196) Merzendorfer H, Kim HS, Chaudhari SS, Kumari M et al (2012) Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneum. Insect Biochem Mol Biol 42:264–276. https://doi.org/10.1016/j.ibmb.2011.12.008. (PMID: 10.1016/j.ibmb.2011.12.008) Metón I, Mediavilla D, Caseras A, Canto E, Fernández F, Baanante IV (1999) Effect of diet composition and ration size on key enzyme activities of glycolysis–gluconeogenesis, the pentose phosphate pathway and amino acid metabolism in liver of gilthead sea bream (Sparusaurata). Brit J Nutr 82:223–232. https://doi.org/10.1017/S0007114599001403. (PMID: 10.1017/S0007114599001403) Moss DW, Henderson AR, Kochmar JF (1986) Enzymes; principles of diagnostic enzymology and the aminotransferases. In: Tietz NW (ed) Textbook of Clinical Chemistry. Saunders, Philadelphia pp, pp 663–678. Mourad NMN, Costa AC, Freitas RTF, Serafini MA, Reis Neto RV, Felizardo VO (2018) Weight and morphometric growth of Pacu (Piaractus mesopotamicus), Tambaqui (Colossoma macropumum) and their hybrids from spring to winter. Pesqui Vet Bras 38:544–550. https://doi.org/10.1590/1678-5150-pvb-4808. (PMID: 10.1590/1678-5150-pvb-4808) Olsvik PA, Samuelsen OB, Erdal A, Holmelid B, Lunestad BT (2013) Toxicological assessment of the anti-salmon lice drug diflubenzuron on Atlantic cod Gadus morhua. Dis Aquat Org 105:27–43. https://doi.org/10.3354/dao02613. (PMID: 10.3354/dao02613) Orchard GE (2013) Pigments and minerals. In. Survarna SK, Layton C, Bancroft JD (eds) Bancroft´s theory and practice of histological techiques. 8th ed, Elsevier, pp.198-230. Pelli A, Paula DR, Arruda AAM, Lopes JM, Ramos SM, Rezende APS (2008) Toxicidade aguda e crônica de diflubenzuron para o jáu, Zungaro zungaro (Humboldt, 1821) (Pisces, Pimelodidae). Revista Brasileira de Zoociências 10:51–54. Petitjean Q, Jean S, Gandar A, Côte J, Laffaille P, Jacquin L (2019) Stress responses in fish: from molecular to evolutionary processes. Sci Total Environ 684:371–380. https://doi.org/10.1016/j.scitotenv.2019.05.357. (PMID: 10.1016/j.scitotenv.2019.05.357) Rath S, Friedlander LG, Reuss R (2015) Residue monograph prepared by the meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), 81st meeting 2015 - Diflubenzuron. pp. 1-32. Ritchie G, Rønsberg SS, Hoff KA, Branson EJ (2002) Clinical efficacy of teflubenzuron (Calicide®) for the treatment of Lepeophtheirus salmonis infestations of farmed Atlantic salmon Salmo salar at low water temperatures. Dis Aquat Org 51:101–106. https://doi.org/10.3354/dao051101. (PMID: 10.3354/dao051101) Schlenk D, Calander M, Gallagher EP, Gorge S, James M, Kulman SW, Van Den Hurk P, Willet K (2008) Biotransformation in Fishe. In.: Di Giulio RT, Hinton DE (eds) The Toxicology of Fishes. CRC Press, USA, pp.154-234. Schulter EP, Vieira Filho JER (2017) Evolução da piscicultura no brasil: diagnóstico e desenvolvimento da cadeia produtiva de tilápia. Texto para discussão / Instituto de Pesquisa Econômica Aplicada – IPEA/Ministério do Planejamento, Desenvolvimento e Gestão, Brasília pp.35. Schwaiger J, Wanke R, Adam S, Pawert M, Honnen W, Triebskorn R (1997) The use of histopathological indicators to evaluated contaminant-related stress in fish. J Aquat Ecosyst Stress Recover 6:75–86. https://doi.org/10.1023/A:1008212000208. (PMID: 10.1023/A:1008212000208) Shiogiri NS, Paulino MG, Carraschi SP, Baraldi FG, Cruz C, Fernandes MN (2012) Acute exposure of a glyphosate-based herbicide affects the gills and liver of the Neotropical fish, Piaractus mesopotamicus. Environ Toxicol Pharmacol 34:388–396. https://doi.org/10.1016/j.etap.2012.05.007. (PMID: 10.1016/j.etap.2012.05.007) Silva JJ, Mendes J (2002) Effects of Diflubenzuron on immature stages of Haematobia irritans (L.) (Diptera: Muscidae) in Uberlândia, State of Minas Gerais, Brazil. Mem Inst Oswaldo Cruz 97:679–682. https://doi.org/10.1590/S0074-02762002000500017. (PMID: 10.1590/S0074-02762002000500017) Solaini G, Baracca A, Lenaz G, Sgarbi G (2010) Hypoxia and mitochondrial oxidative metabolism. Biochim Biophys Acta Bioenerg 1797:1171–1177. https://doi.org/10.1016/j.bbabio.2010.02.011. (PMID: 10.1016/j.bbabio.2010.02.011) Strnad P, Stumptner C, Zatloukal K, Denk H (2008) Intermediate Wlament cytoskeleton of the liver in health and disease. Histochem Cell Biol 129:735–749. https://doi.org/10.1007/s00418-008-0431-x. (PMID: 10.1007/s00418-008-0431-x) Strnad P, Nuraldeen R, Guldiken N, Hartmann D, Mahajan V, Denk H, Haybaeck J (2013) Broad spectrum of hepatocyte inclusions in humans, animals, and experimental models. Compr Physiol 3:1393–1436. https://doi.org/10.1002/cphy.c120032. (PMID: 10.1002/cphy.c120032) Tavares-Dias M, Martins ML (2017) An overall estimation of losses caused by diseases in the Brazilian fish farms. J Parasit Dis 41:913–918. https://doi.org/10.1007/s12639-017-0938-y. (PMID: 10.1007/s12639-017-0938-y) Ursus-Nikolaus R, Werner M (2004) Color Atlas of Pathology. Pathologic Principes, Associated Diseases. Sequeles. Thieme, Stuttgard, Germany, p 457. Vassiliou G (2016) Factors affecting risk assessment of pesticides in water bodies: a review. MOJ Toxicology 2:26–32. (PMID: 10.15406/mojt.2016.02.00030) Walling MA, Janovitz EB (2018) Morphological manifestations of toxic cell injury. In.:Wallig MA, Bolon B, Haschek WM, Rousseaux CG (eds) Fundamentals of toxicologic pathology, Academic Press, pp.59-81. WHO (2008) Diflubenzuron in drinking water: use for vector control in drinking-water sources and containers. Background document for development of WHO guidelines for drinking-water quality. Available at www.who.int/water_sanitation_health/dwq/chemicals/phe_wsh_diflubenzuron_fact_sheet.pdf . Accessed 23 April 2020. Wolf JC, Wolfe MJ (2005) A brief overview of nonneoplastic hepatic toxicity in fish. Toxicol Pathol 33:75–85. https://doi.org/10.1080/01926230590890187. (PMID: 10.1080/01926230590890187) |
| معلومات مُعتمدة: | Finance Code 001 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; FUNDECT/CAPES n° 07/2015 Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul |
| فهرسة مساهمة: | Keywords: ALT; AST; Fish; Histopathology; Liver; Xenobiotics |
| المشرفين على المادة: | 0 (Insecticides) EC 2.6.1.2 (Alanine Transaminase) J76U6ZSI8D (Diflubenzuron) |
| تواريخ الأحداث: | Date Created: 20210107 Date Completed: 20210512 Latest Revision: 20210512 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1007/s11356-020-12013-2 |
| PMID: | 33410075 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1614-7499 |
|---|---|
| DOI: | 10.1007/s11356-020-12013-2 |