دورية أكاديمية
[Autopsies are essential for a better knowledge and prevention of sudden cardiac death].
| العنوان: | [Autopsies are essential for a better knowledge and prevention of sudden cardiac death]. |
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| عنوان ترانسليتريتد: | L’autopsie : indispensable pour la connaissance et la prévention de la mort subite cardiaque. |
| المؤلفون: | Fornès P; Laboratoire de biopathologie, hôpital Robert-Debré, institut-médico-légal, CHU, avenue du Général-Koenig, 51100 Reims, France. Electronic address: pfornes@chu-reims.fr., Callon D; Laboratoire de biopathologie, hôpital Robert-Debré, institut-médico-légal, CHU, avenue du Général-Koenig, 51100 Reims, France. |
| المصدر: | Annales de pathologie [Ann Pathol] 2021 Feb; Vol. 41 (1), pp. 85-96. Date of Electronic Publication: 2021 Jan 04. |
| نوع المنشور: | Journal Article |
| اللغة: | French |
| بيانات الدورية: | Publisher: Masson Country of Publication: France NLM ID: 8106337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0242-6498 (Print) Linking ISSN: 02426498 NLM ISO Abbreviation: Ann Pathol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Paris ; New York : Masson, c1981- |
| مواضيع طبية MeSH: | Coronary Artery Disease* , Death, Sudden, Cardiac*/etiology , Death, Sudden, Cardiac*/prevention & control, Autopsy ; Cause of Death ; Humans ; Incidence |
| مستخلص: | In France, the incidence of sudden cardiac deaths (SCD) is approximately 30,000-50,000 per year. In the whole population, their cause is an atherosclerotic coronary disease in more than 80 % of cases, but in the young (<35 years old), causes are various, including genetic, infectious, toxic, congenital anomalies, immune…Therefore a multidisciplinary approach is required for a better knowledge and prevention of SCD. In this article, we examine different aspects of autopsies and complementary investigations: histopathology, toxicology, biochemistry, genetics and virology. Six cases illustrate the importance of a multidisciplinary approach. There are two categories of autopsies: medicolegal or medical. Medicolegal autopsies are requested by a judicial authority when a death is considered suspicious. These autopsies are performed by forensic doctors. Most of them are not pathologists. During the autopsies, blood and tissue samples are taken, but analyses are done only at the request of the judicial authority if the analyses are useful for the truth. Consequently, the cause of death can remain uncertain. Medical autopsies are performed by a pathologist at the request of a clinician. The family consent is required. Useful analyses are performed, which is essential for the determination of a precise cause of death. In the young, "molecular autopsy", in addition to histology and other analyses, is essential in preventing genetic causes of SCD. (Copyright © 2020 Elsevier Masson SAS. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Autopsie; Autopsy; Cœur; Forensics; Genetics; Génétique; Heart; Histopathologie; Histopathology; Mort subite; Médecine légale; Sudden death; Virologie; Virology |
| تواريخ الأحداث: | Date Created: 20210108 Date Completed: 20211015 Latest Revision: 20211015 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.annpat.2020.09.008 |
| PMID: | 33413973 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0242-6498 |
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| DOI: | 10.1016/j.annpat.2020.09.008 |