دورية أكاديمية
Smell Status in Children Infected with SARS-CoV-2.
العنوان: | Smell Status in Children Infected with SARS-CoV-2. |
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المؤلفون: | Rusetsky Y; Otorhinolaryngological surgical department with a group of head and neck diseases, National Medical Research Center of Children's Health, Moscow, Russia.; Department of ear, nose and throat diseases, Central State Medical Academy, Moscow, Russia., Meytel I; Otorhinolaryngological surgical department with a group of head and neck diseases, National Medical Research Center of Children's Health, Moscow, Russia., Mokoyan Z; Department of ear, nose and throat diseases, I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Fisenko A; Otorhinolaryngological surgical department with a group of head and neck diseases, National Medical Research Center of Children's Health, Moscow, Russia., Babayan A; Otorhinolaryngological surgical department with a group of head and neck diseases, National Medical Research Center of Children's Health, Moscow, Russia., Malyavina U; Otorhinolaryngological surgical department with a group of head and neck diseases, National Medical Research Center of Children's Health, Moscow, Russia. |
المصدر: | The Laryngoscope [Laryngoscope] 2021 Aug; Vol. 131 (8), pp. E2475-E2480. Date of Electronic Publication: 2021 Jan 18. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8607378 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-4995 (Electronic) Linking ISSN: 0023852X NLM ISO Abbreviation: Laryngoscope Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2009- >: Philadelphia, PA : Wiley-Blackwell Original Publication: St. Louis, Mo. : [s.n., 1896- |
مواضيع طبية MeSH: | SARS-CoV-2*, Anosmia/*epidemiology , COVID-19/*complications , Olfaction Disorders/*epidemiology, Adolescent ; Anosmia/diagnosis ; Anosmia/virology ; COVID-19/physiopathology ; COVID-19/virology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Male ; Odorants/analysis ; Olfaction Disorders/diagnosis ; Olfaction Disorders/virology ; Prospective Studies ; Psychophysics ; Smell/physiology ; Surveys and Questionnaires ; Symptom Assessment/methods |
مستخلص: | Objectives/hypothesis: This study aimed to evaluate the olfactory status in children with laboratory confirmed SARS-CoV-2 using subjective and psychophysical methods. Study Design: Prospective clinical cross-sectional study. Methods: This is a prospective clinical cross-sectional study of 79 children with COVID-19. The 21st item of SNOT-22 questionnaire and odor identification test were used for smell assessment. Children were examined twice during the hospitalization, and a telephone survey was conducted 60 days after hospital discharge. Results: Immediately after confirmation of COVID-19, smell impairment was detected in 86.1% of children by means of the Identification test and in 68.4% of children by means of the survey (P = .010). After 5 days survey revealed a statistically significant decrease in the number of patients with hyposmia (41 out of 79, 51.9%). On the first visit, the mean Identification test score corresponded to "hyposmia" (9.5 ± 2.7), while on the second visit, the average value was 13.1 ± 1.9, which corresponded to "normosmia." According to the telephone survey, recovery of the olfactory function occurred within 10 days in 37 of 52 patients (71.2%), 11 to 29 days - in 12 children (23.1%), and later than 30 days - in three cases (5.7%). Conclusions: In the pediatric population, olfactory dysfunction is an early and common symptom of COVID-19. There is a trend to quick recovery of olfactory function in children with COVID-19. The overwhelming majority of patients (94.3%) had no subjective olfactory complaints by the end of the first month. Level of Evidence: 4 Laryngoscope, 131:E2475-E2480, 2021. (© 2021 The American Laryngological, Rhinological and Otological Society, Inc.) |
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فهرسة مساهمة: | Keywords: Anosmia; COVID-19; SARS-CoV-2; children; hyposmia; pandemic; smell |
تواريخ الأحداث: | Date Created: 20210114 Date Completed: 20210720 Latest Revision: 20221005 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC8013292 |
DOI: | 10.1002/lary.29403 |
PMID: | 33443298 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1531-4995 |
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DOI: | 10.1002/lary.29403 |