دورية أكاديمية

[Histopathological features due to the SARS-CoV-2].

التفاصيل البيبلوغرافية
العنوان: [Histopathological features due to the SARS-CoV-2].
عنوان ترانسليتريتد: Les lésions histologiques associées à l’infection par le SARS-CoV-2.
المؤلفون: Hofman P; Laboratoire de pathologie clinique et expérimentale, hôpital Pasteur, centre hospitalo-universitaire de Nice, université Côte d'Azur, B.P. 69-30, avenue de la voie romaine, 06001 Nice cedex 01, France; Biobanque hospitalière (BB-0033-00025), hôpital Pasteur, Nice, France; FHU OncoAge, hôpital Pasteur, Nice, France. Electronic address: hofman.p@chu-nice.fr., Copin MC; Université d'Angers, Inserm, CRCINA, Angers, France; Département de pathologie, centre hospitalo-universitaire, Angers, France., Tauziede-Espariat A; Service de neuropathologie, GHU de Paris psychiatrie et neurosciences, hôpital Saint-Anne, Paris, France., Adle-Biassette H; Service de pathologie, hôpital Lariboisière, AP-HP, Paris, France., Fortarezza F; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova Medical School, Padova, Italie., Passeron T; Département de dermatologie, hôpital Archet II, centre hospitalo-universitaire de nice, université Côte d'Azur, Nice, France., Salmon I; Département de pathologie, hôpital Erasme, université Libre de Bruxelles, Bruxelles, Belgique., Calabrese F; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova Medical School, Padova, Italie.
المصدر: Annales de pathologie [Ann Pathol] 2021 Feb; Vol. 41 (1), pp. 9-22. Date of Electronic Publication: 2020 Dec 30.
نوع المنشور: Journal Article; Review
اللغة: French
بيانات الدورية: Publisher: Masson Country of Publication: France NLM ID: 8106337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0242-6498 (Print) Linking ISSN: 02426498 NLM ISO Abbreviation: Ann Pathol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Paris ; New York : Masson, c1981-
مواضيع طبية MeSH: COVID-19/*pathology, Autopsy ; COVID-19/virology ; Fibrosis/pathology ; Fibrosis/virology ; Histocytochemistry ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Kidney/pathology ; Kidney/virology ; Liver/pathology ; Liver/virology ; Lung/pathology ; Lung/virology ; SARS-CoV-2/pathogenicity ; Skin/pathology ; Skin/virology ; Thrombosis/pathology ; Thrombosis/virology
مستخلص: The infection due to the SARS-CoV-2 leads lesions mainly observed at the respiratory tract level, but not exclusively. The analyses of these lesions benefited from different autopsy studies. Thus, these lesions were observed in different organs, tissues and cells. These observations allowed us to rapidly improve the knowledge of the pathophysiological mechanisms associated with this emergent infectious disease. The virus can be detected in formalin fixed paraffin embedded tissues using immunohistochemistry, in situ hybridization, molecular biology and/or electron microscopy approaches. However, many uncertainties are still present concerning the direct role of the SARS-CoV-2 on the different lesions observed in different organs, outside the lung, such as the heart, the brain, the liver, the gastrointestinal tract, the kidney and the skin. In this context, it is pivotal to keep going to increase the different tissue and cellular studies in the COVID-19 positive patients aiming to better understanding the consequences of this new infectious disease, notably considering different epidemiological and co-morbidities associated factors. This could participate to the development of new therapeutic strategies too. The purpose of this review is to describe the main histological and cellular lesions associated with the infection due to the SARS-CoV-2.
(Copyright © 2020 Elsevier Masson SAS. All rights reserved.)
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فهرسة مساهمة: Keywords: Ancillary tools; Autopsie; Autopsy; COVID-19; Pathologie; Pathology; Pathophysiology; Physiopathologie; Études ancillaires
تواريخ الأحداث: Date Created: 20210115 Date Completed: 20210219 Latest Revision: 20240330
رمز التحديث: 20240330
مُعرف محوري في PubMed: PMC7773006
DOI: 10.1016/j.annpat.2020.12.009
PMID: 33446414
قاعدة البيانات: MEDLINE
الوصف
تدمد:0242-6498
DOI:10.1016/j.annpat.2020.12.009