دورية أكاديمية
Genomic adaptation of Pseudomonas strains to acidity and antibiotics in hydrothermal vents at Kolumbo submarine volcano, Greece.
العنوان: | Genomic adaptation of Pseudomonas strains to acidity and antibiotics in hydrothermal vents at Kolumbo submarine volcano, Greece. |
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المؤلفون: | Bravakos P; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece., Mandalakis M; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece., Nomikou P; Department of Geology and Geoenvironment, National and Kapodistrian University of Athens, Athens, Greece., Anastasiou TI; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece., Kristoffersen JB; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece., Stavroulaki M; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece., Kilias S; Department of Geology and Geoenvironment, National and Kapodistrian University of Athens, Athens, Greece., Kotoulas G; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece., Magoulas A; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece., Polymenakou PN; Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research (IMBBC-HCMR), Gournes Pediados, Heraklion Crete, Greece. polymen@hcmr.gr. |
المصدر: | Scientific reports [Sci Rep] 2021 Jan 14; Vol. 11 (1), pp. 1336. Date of Electronic Publication: 2021 Jan 14. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
مواضيع طبية MeSH: | Genome, Bacterial*, Adaptation, Physiological/*genetics , Drug Resistance, Multiple, Bacterial/*genetics , Hydrothermal Vents/*microbiology , Pseudomonas/*genetics , Seawater/*microbiology, Greece ; Pseudomonas/isolation & purification |
مستخلص: | Although the rise of antibiotic and multidrug resistant bacteria is one of the biggest current threats to human health, our understanding of the mechanisms involved in antibiotic resistance selection remains scarce. We performed whole genome sequencing of 21 Pseudomonas strains, previously isolated from an active submarine volcano of Greece, the Kolumbo volcano. Our goal was to identify the genetic basis of the enhanced co-tolerance to antibiotics and acidity of these Pseudomonas strains. Pangenome analysis identified 10,908 Gene Clusters (GCs). It revealed that the numbers of phage-related GCs and sigma factors, which both provide the mechanisms of adaptation to environmental stressors, were much higher in the high tolerant Pseudomonas strains compared to the rest ones. All identified GCs of these strains were associated with antimicrobial and multidrug resistance. The present study provides strong evidence that the CO |
References: | Clin Microbiol Infect. 2009 Jan;15 Suppl 1:20-5. (PMID: 19220348) Metab Eng. 2017 Sep;43(Pt B):113-124. (PMID: 28192215) Methods Mol Biol. 2014;1079:155-70. (PMID: 24170401) Science. 1994 Apr 15;264(5157):375-82. (PMID: 8153624) Bioinformatics. 2019 Nov 1;35(21):4453-4455. (PMID: 31070718) Sci Rep. 2013;3:2421. (PMID: 23939372) BMC Bioinformatics. 2010 Mar 08;11:119. (PMID: 20211023) Environ Microbiol Rep. 2013 Feb;5(1):127-34. (PMID: 23757141) Appl Environ Microbiol. 2015 Nov;81(21):7593-9. (PMID: 26296734) Environ Microbiol. 2016 Apr;18(4):1122-36. (PMID: 26487573) Mol Biol Evol. 2018 Jun 1;35(6):1547-1549. (PMID: 29722887) Res Microbiol. 2015 Jun;166(5):448-457. (PMID: 25908548) Cell Signal. 2013 Jul;25(7):1608-13. (PMID: 23602932) Front Microbiol. 2011 Nov 29;2:238. (PMID: 22347872) Nat Biotechnol. 2018 Nov;36(10):996-1004. (PMID: 30148503) PLoS One. 2011 Mar 03;6(3):e17549. (PMID: 21390233) Genome Biol. 2004;5(2):R12. (PMID: 14759262) Environ Microbiol. 2009 Aug;11(8):2148-63. (PMID: 19397678) PLoS Pathog. 2015 Mar 17;11(3):e1004744. (PMID: 25780925) Microb Biotechnol. 2020 Jan;13(1):32-53. (PMID: 30883020) Infect Drug Resist. 2018 Apr 11;11:523-530. (PMID: 29695921) Nucleic Acids Res. 2015 Jul 1;43(W1):W7-14. (PMID: 25883146) Appl Microbiol Biotechnol. 2010 May;86(6):1659-70. (PMID: 20352425) Can J Microbiol. 2009 Jan;55(1):37-45. (PMID: 19190699) Mol Biol Evol. 2007 Aug;24(8):1586-91. (PMID: 17483113) BMC Genomics. 2014 Jan 03;15:8. (PMID: 24387194) PeerJ. 2018 Jan 25;6:e4320. (PMID: 29423345) J Mol Biol. 2004 May 14;338(5):1027-36. (PMID: 15111065) Extremophiles. 2018 Jan;22(1):13-27. (PMID: 29067531) ISME J. 2011 Jan;5(1):51-60. (PMID: 20668489) Bioinformatics. 2015 Oct 1;31(19):3210-2. (PMID: 26059717) Environ Microbiol. 2018 Jun;20(6):2142-2159. (PMID: 29633519) Nucleic Acids Res. 2021 Jan 8;49(D1):D545-D551. (PMID: 33125081) Microb Biotechnol. 2019 Sep;12(5):993-1002. (PMID: 31270958) Front Microbiol. 2015 Mar 18;6:214. (PMID: 26074881) Bioinformatics. 2005 Sep 15;21(18):3674-6. (PMID: 16081474) Microorganisms. 2016 Feb 16;4(1):. (PMID: 27681908) J Comput Biol. 2012 May;19(5):455-77. (PMID: 22506599) Science. 2012 Aug 31;337(6098):1107-11. (PMID: 22936781) Cell. 2017 Oct 5;171(2):273-285. (PMID: 28985560) Appl Environ Microbiol. 2012 Apr;78(7):2128-36. (PMID: 22286981) Bioinformatics. 2011 Apr 15;27(8):1164-5. (PMID: 21335321) Science. 2008 Jul 18;321(5887):365-7. (PMID: 18635792) Genome Res. 2015 Jul;25(7):1043-55. (PMID: 25977477) Protein Sci. 2019 Nov;28(11):1947-1951. (PMID: 31441146) In Vivo. 2020 Jan-Feb;34(1):65-71. (PMID: 31882464) ACS Chem Biol. 2012 Jan 20;7(1):197-209. (PMID: 21999246) Front Cell Infect Microbiol. 2017 Feb 15;7:39. (PMID: 28261568) Nucleic Acids Res. 2000 Jan 1;28(1):27-30. (PMID: 10592173) Int J Syst Evol Microbiol. 2003 Mar;53(Pt 2):393-400. (PMID: 12710603) Mar Environ Res. 2019 Feb;144:102-110. (PMID: 30654982) Environ Microbiol. 2004 Sep;6(9):981-9. (PMID: 15305923) Front Neurosci. 2018 Apr 17;12:249. (PMID: 29719499) FEMS Microbiol Rev. 2011 Jul;35(4):652-80. (PMID: 21361996) Nucleic Acids Res. 2004 Mar 19;32(5):1792-7. (PMID: 15034147) Syst Biol. 2010 May;59(3):307-21. (PMID: 20525638) |
تواريخ الأحداث: | Date Created: 20210115 Date Completed: 20210810 Latest Revision: 20240330 |
رمز التحديث: | 20240330 |
مُعرف محوري في PubMed: | PMC7809023 |
DOI: | 10.1038/s41598-020-79359-y |
PMID: | 33446715 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2045-2322 |
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DOI: | 10.1038/s41598-020-79359-y |