دورية أكاديمية
Three Cases of Clear Cell Hidradenoma With "Benign" Lymph Node Involvement.
| العنوان: | Three Cases of Clear Cell Hidradenoma With "Benign" Lymph Node Involvement. |
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| المؤلفون: | Gonzalez-Lopez G; Department of Pathology, Hospital Universitario Doce de Octubre, Universidad Complutense, Instituto de Investigación I+12, Madrid, Spain; and., Garrido-Ruiz MC; Department of Pathology, Hospital Universitario Doce de Octubre, Universidad Complutense, Instituto de Investigación I+12, Madrid, Spain; and., Rios-Martin JJ; Department of Pathology, Hospital Universitario Virgen de la Macarena, Sevilla, Spain., Rodriguez-Peralto JL; Department of Pathology, Hospital Universitario Doce de Octubre, Universidad Complutense, Instituto de Investigación I+12, Madrid, Spain; and. |
| المصدر: | The American Journal of dermatopathology [Am J Dermatopathol] 2021 Jun 01; Vol. 43 (6), pp. e76-e79. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7911005 Publication Model: Print Cited Medium: Internet ISSN: 1533-0311 (Electronic) Linking ISSN: 01931091 NLM ISO Abbreviation: Am J Dermatopathol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: New York, Masson Publishing USA. |
| مواضيع طبية MeSH: | Acrospiroma/*pathology , Lymphatic Metastasis/*pathology , Sweat Gland Neoplasms/*pathology, Adult ; Humans ; Male ; Middle Aged |
| مستخلص: | Abstract: The malignant counterpart of cutaneous clear cell hidradenoma (CCH), hidradenocarcinoma, is an aggressive neoplasm that may have a fatal outcome. However, some cases of benign looking CCH with isolated lymph node involvement and excellent prognosis have been described. "CCH-like neoplasm of uncertain malignant potential" or "atypical hidradenoma" have been proposed as designations for these lesions. We report 3 cases of CCH with lymph node involvement. Ages ranged from 29 to 51 years old. All cases involved the inguinal lymph nodes: 2 of them presented with an isolated lymph node lesion, and the third case had lymph node and cutaneous involvement following the resection of a previous cutaneous lesion. Imaging studies showed no systemic involvement. None of the lesions exhibited histopathologic features of malignancy. All neoplasms were well circumscribed, had cystic spaces, did not display atypia or necrosis, and had less than 4 mitoses per high power field. No recurrence has been observed at follow-up after resection in all cases. All published cases of CCH with lymph node involvement so far affected a single lymph node in the axillary or inguinal regions, lacked features of malignancy, and had excellent long-term prognosis. Some cases previously reported as hidradenocarcinoma probably fit into this category. Our series adds more evidence to this rare phenomenon of "benign metastasis." Aggressive treatment should be avoided in these cases, and a long-term follow-up is warranted. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.) |
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| تواريخ الأحداث: | Date Created: 20210119 Date Completed: 20211122 Latest Revision: 20230928 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1097/DAD.0000000000001886 |
| PMID: | 33464750 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1533-0311 |
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| DOI: | 10.1097/DAD.0000000000001886 |