دورية أكاديمية
أعرض في EDS

Space-time risk cluster of visceral leishmaniasis in Brazilian endemic region with high social vulnerability: An ecological time series study.

التفاصيل البيبلوغرافية
العنوان: Space-time risk cluster of visceral leishmaniasis in Brazilian endemic region with high social vulnerability: An ecological time series study.
المؤلفون: Ribeiro CJN; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil., Dos Santos AD; Department of Nursing, Federal University of Sergipe, Lagarto, Brazil., Lima SVMA; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Department of Nursing, Federal University of Sergipe, Lagarto, Brazil., da Silva ER; Department of Nursing, Federal University of Sergipe, Aracaju, Brazil., Ribeiro BVS; Graduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, Brazil., Duque AM; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil., Peixoto MVS; Department of Speech Therapy and Audiology, Federal University of Sergipe, São Cristóvão, Brazil., Dos Santos PL; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Graduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, Brazil., de Oliveira IM; Department of Functional Biology and Health Sciences, University of Vigo, Pontevedra, Spain., Lipscomb MW; Department of Biology, Howard University, Washington DC, United States of America., de Araújo KCGM; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Graduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, Brazil., de Moura TR; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Graduate Program in Parasite Biology, Federal University of Sergipe, São Cristóvão, Brazil.
المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Jan 19; Vol. 15 (1), pp. e0009006. Date of Electronic Publication: 2021 Jan 19 (Print Publication: 2021).
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Socioeconomic Factors* , Spatio-Temporal Analysis*, Leishmaniasis, Visceral/*epidemiology, Adolescent ; Adult ; Brazil/epidemiology ; Child ; Child, Preschool ; Female ; Humans ; Incidence ; Infant ; Leishmaniasis, Visceral/transmission ; Male ; Middle Aged ; Vulnerable Populations
مستخلص: Background: Despite visceral leishmaniasis (VL) being epidemic in most Brazilian regions, the Northeast region is responsible for the highest morbidity and mortality outcomes within the country.
Objective: To analyse the spatiotemporal dynamics of VL cases to identify the temporal trends and high-risk areas for VL transmission, as well as the association of the disease with social vulnerability in Brazilian Northeast.
Methods: We carried out an ecological time series study employing spatial analysis techniques using all VL confirmed cases of 1,794 municipalities of Brazilian Northeast between the years 2000 to 2017. The Social Vulnerability Index (SVI) was used to represent the social vulnerability. Incidence rates were standardized and smoothed by the Local Empirical Bayesian Method. Time trends were examined through segmented linear regression. Spatiotemporal analysis consisted of uni- and bivariate Global and Local Moran indexes and space-time scan statistics.
Results: Incidence rate remained stable and ranged from 4.84 to 3.52 cases/100,000 inhabitants. There was higher case prevalence between males (62.71%), children and adolescents (63.27%), non-white (69.75%) and urban residents (62.58%). Increasing trends of new cases were observed among adult male subjects (≥ 40 years old) and urban residents. Importantly, VL incidence showed a direct spatial dependence. Spatial and space-time clusters were identified in sertão and meio-norte sub-regions, overlapping with high social vulnerability areas.
Conclusions: VL is a persistent health issue in Brazilian Northeast and associated with social vulnerability. Space-time clustering of VL cases in socially vulnerable municipalities demands intersectoral public policies of surveillance and control, with focus on reducing inequalities and improving living conditions for regional inhabitants.
Competing Interests: The authors have declared that no competing interests exist.
References: HIV AIDS (Auckl). 2016 Mar 23;8:75-81. (PMID: 27042142)
Rev Soc Bras Med Trop. 2018 Jul-Aug;51(4):452-460. (PMID: 30133627)
Trans R Soc Trop Med Hyg. 2018 Jul 23;:. (PMID: 30053165)
J Eur Acad Dermatol Venereol. 2019 Aug;33(8):1581-1590. (PMID: 30903718)
Int J Equity Health. 2016 Nov 17;15(1):177. (PMID: 27852310)
Trop Med Int Health. 2009 Jun;14(6):639-44. (PMID: 19392741)
J Vector Borne Dis. 2016 Jul-Sep;53(3):193-8. (PMID: 27681541)
PLoS Negl Trop Dis. 2015 Aug 14;9(8):e0003982. (PMID: 26274916)
Rev Panam Salud Publica. 2014 Jul;36(1):24-30. (PMID: 25211674)
Rev Bras Epidemiol. 2012 Jun;15(2):298-307. (PMID: 22782095)
Lancet. 2011 May 28;377(9780):1877-89. (PMID: 21561657)
PLoS Negl Trop Dis. 2017 Mar 9;11(3):e0005231. (PMID: 28278151)
Cad Saude Publica. 1998 Oct-Dec;14(4):713-23. (PMID: 9878904)
PLoS Negl Trop Dis. 2014 Dec 11;8(12):e3374. (PMID: 25503575)
Acta Trop. 2014 Mar;131:56-62. (PMID: 24342506)
Asian Pac J Trop Med. 2016 Oct;9(10):925-932. (PMID: 27794384)
Cien Saude Colet. 2017 Apr;22(4):1055-1064. (PMID: 28444033)
Parasite Epidemiol Control. 2016 Apr 07;1(2):56-65. (PMID: 29988194)
Stat Med. 2000 Feb 15;19(3):335-51. (PMID: 10649300)
Trans R Soc Trop Med Hyg. 2014 Jun;108(6):338-47. (PMID: 24706340)
Soc Sci Med. 2018 Feb;199:11-18. (PMID: 29325781)
Geospat Health. 2017 May 11;12(1):503. (PMID: 28555473)
Braz J Infect Dis. 2015 Nov-Dec;19(6):651-6. (PMID: 26361839)
Am J Trop Med Hyg. 2016 Mar;94(3):489-93. (PMID: 26787156)
Pathog Glob Health. 2015 Sep;109(6):283-9. (PMID: 26257311)
PLoS Negl Trop Dis. 2018 Dec 6;12(12):e0006888. (PMID: 30521529)
Rev Inst Med Trop Sao Paulo. 2016;58:29. (PMID: 27074323)
Clin Microbiol Rev. 2014 Oct;27(4):949-79. (PMID: 25278579)
Rev Soc Bras Med Trop. 2019 Mar 18;52:e20180257. (PMID: 30892399)
BMC Public Health. 2019 Jul 4;19(1):873. (PMID: 31272437)
Environ Monit Assess. 2019 Jun 28;191(Suppl 2):331. (PMID: 31254126)
Rev Soc Bras Med Trop. 2016 Sep-Oct;49(5):608-615. (PMID: 27812656)
PLoS Negl Trop Dis. 2018 Mar 6;12(3):e0006164. (PMID: 29509765)
Infect Dis Poverty. 2017 Feb 8;6(1):20. (PMID: 28173858)
Int J Health Geogr. 2014 May 20;13:13. (PMID: 24885128)
Acta Trop. 2019 Sep;197:105052. (PMID: 31233726)
Rev Soc Bras Med Trop. 2017 Jan-Feb;50(1):104-109. (PMID: 28327810)
Rev Inst Med Trop Sao Paulo. 2018 Oct 25;60:e62. (PMID: 30379229)
Ann Epidemiol. 2016 Apr;26(4):238-40. (PMID: 27084546)
Int Health. 2016 Mar;8 Suppl 1:i53-70. (PMID: 26940310)
Rev Inst Med Trop Sao Paulo. 2020 Feb 14;62:e12. (PMID: 32074215)
Trop Med Int Health. 2020 Feb;25(2):193-208. (PMID: 31713982)
J Vector Borne Dis. 2016 Apr-Jun;53(2):99-104. (PMID: 27353578)
Trends Parasitol. 2019 Feb;35(2):97-101. (PMID: 30554966)
PLoS Negl Trop Dis. 2018 Sep 6;12(9):e0006697. (PMID: 30188898)
PLoS Negl Trop Dis. 2010 Jan 19;4(1):e584. (PMID: 20098726)
Rev Saude Publica. 2017 May 15;51(0):49. (PMID: 28513764)
Rev Soc Bras Med Trop. 2019 Dec 20;53:e20190262. (PMID: 31859950)
PLoS One. 2014 Apr 03;9(4):e93770. (PMID: 24699517)
PLoS Negl Trop Dis. 2017 Oct 6;11(10):e0005950. (PMID: 28985218)
Microbes Infect. 2014 Aug;16(8):601-6. (PMID: 25088506)
An Bras Dermatol. 2019 Mar-Apr;94(2):182-191. (PMID: 31090823)
Cien Saude Colet. 2015 Dec;20(12):3935-42. (PMID: 26691816)
معلومات مُعتمدة: SC1 GM127207 United States GM NIGMS NIH HHS
تواريخ الأحداث: Date Created: 20210119 Date Completed: 20210506 Latest Revision: 20210604
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC7846114
DOI: 10.1371/journal.pntd.0009006
PMID: 33465104
قاعدة البيانات: MEDLINE
الوصف
تدمد:1935-2735
DOI:10.1371/journal.pntd.0009006