دورية أكاديمية
Cerebral Toxocariasis as a Cause of Epilepsy: A Pediatric Case.
| العنوان: | Cerebral Toxocariasis as a Cause of Epilepsy: A Pediatric Case. |
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| المؤلفون: | Bossi G; Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Bruno R; Department of Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Clinical-Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy., Novati S; Department of Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Maserati R; Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Mussati G; Department of Diagnostic and Interventional Radiology and Neuroradiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Gorone MP; Pediatric Radiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Nepita EV; Molecular Virology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Regalbuto C; Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Gola G; Department of Diagnostic and Interventional Radiology and Neuroradiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Simoncelli AM; Department of Diagnostic and Interventional Radiology and Neuroradiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Bruno A; Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Musso P; Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Clerici E; Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Marseglia GL; Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Clinical-Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy. |
| المصدر: | Neuropediatrics [Neuropediatrics] 2021 Apr; Vol. 52 (2), pp. 142-145. Date of Electronic Publication: 2021 Jan 20. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Hippokrates Verlag Country of Publication: Germany NLM ID: 8101187 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-1899 (Electronic) Linking ISSN: 0174304X NLM ISO Abbreviation: Neuropediatrics Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Stuttgart : Hippokrates Verlag Original Publication: Stuttgart [Germany] : Hippokrates Verlag, [1980]- |
| مواضيع طبية MeSH: | Brain Abscess*/diagnosis , Brain Abscess*/drug therapy , Brain Abscess*/etiology , Central Nervous System Helminthiasis*/complications , Central Nervous System Helminthiasis*/diagnosis , Central Nervous System Helminthiasis*/drug therapy , Epilepsy*/diagnosis , Epilepsy*/drug therapy , Epilepsy*/etiology , Toxocariasis*/complications , Toxocariasis*/diagnosis , Toxocariasis*/drug therapy, Antiparasitic Agents/*pharmacology , Steroids/*pharmacology , Toxocara canis/*pathogenicity, Albendazole/administration & dosage ; Animals ; Antiparasitic Agents/administration & dosage ; Child ; Humans ; Larva ; Steroids/administration & dosage |
| مستخلص: | Toxocarosis is the consequence of human infection by Toxocara spp. larvae and is one of the most common ascarioses, not only in developing countries, but also in the European region, where its prevalence reaches 14%. Due to their particular behavior, children are at higher risk of this parasitic infection, whose clinical features depend on the localization of the Toxocara larvae. Neurotoxocariasis is very uncommon in children and may take different forms depending on the underlying physiopathologic process: immune reaction against the parasite antigens, vasculitis, treatment complications, or, very rarely, brain localization of Toxocara spp. larvae. The association between neurotoxocariasis and the onset of childhood epilepsy has been postulated but is still debated. Moreover, a Toxocara spp. abscess causing epileptic seizures in children has been rarely described, especially in western countries. Hereby we present a 9-year-old patient with a new diagnosis of epilepsy definitely secondary to brain abscess due to the localization of Toxocara canis larvae. Diagnosis was confirmed by neuroimaging and serological test. The successful treatment with albendazole and steroids was documented with a close and long-term clinical and neuroradiological follow-up. Our experience confirms that every case of cryptogenetic epilepsy in children deserves a neuroimaging study and, in case of cystic images, Toxocara serology is mandatory to avoid further unnecessary invasive diagnostic investigations and to set the specific drug therapy. Competing Interests: None declared. (Thieme. All rights reserved.) |
| المشرفين على المادة: | 0 (Antiparasitic Agents) 0 (Steroids) F4216019LN (Albendazole) |
| تواريخ الأحداث: | Date Created: 20210120 Date Completed: 20211108 Latest Revision: 20211108 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1055/s-0040-1721701 |
| PMID: | 33472248 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1439-1899 |
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| DOI: | 10.1055/s-0040-1721701 |