دورية أكاديمية
Age-dependent histomorphometric evolution of the corpus spongiosum.
| العنوان: | Age-dependent histomorphometric evolution of the corpus spongiosum. |
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| المؤلفون: | Pigatto Filho G; Fellow Master degree, Postgraduate Program in Surgical Clinic, Universidade Federal do Paraná, Curitiba-PR, Brazil., Zeni M; Msc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil., Melchioretto EF; Msc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil., Marques GL; Msc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil., Hota T; Msc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil., Fraga R; PhD, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil. |
| المصدر: | Acta cirurgica brasileira [Acta Cir Bras] 2021 Jan 20; Vol. 35 (12), pp. e351203. Date of Electronic Publication: 2021 Jan 20 (Print Publication: 2021). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina Country of Publication: Brazil NLM ID: 9103983 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2674 (Electronic) Linking ISSN: 01028650 NLM ISO Abbreviation: Acta Cir Bras Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Sao Paulo : Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina Original Publication: São Paulo : A Sociedade, |
| مواضيع طبية MeSH: | Elastic Tissue* , Penis*, Aging ; Animals ; Collagen ; Collagen Type I ; Male ; Rats |
| مستخلص: | Purpose: To quantify the age-dependent changes in the relative volume of elastic fibers, collagen fibers and the proportion of collagen types I/III in the corpus spongiosum of rats. Methods: Forty-eight rats, raised under similar conditions, were divided into four groups (G1 to G4) and underwent penectomy at the ages of 6, 9, 12 and 24 months, respectively. Histological sections from the middle segment of the penis were stained with Weigert's resorcin-fuchsin, Masson's trichrome and Picrosirius red, the volumetric density of elastic fibers, collagen fibers and the proportion of collagen types I and III in the corpus spongiosum were determined by stereological analysis. Results: A reduction in the proportion of collagen I/III between the groups G3 and G4 (p < 0.048) was observed. In the volumetric analysis of elastic fiber, we observed a significant rise between the groups G2 and G3 (p < 0.03) and a reduction of the volume between the groups G3 and G4 (p < 0.01). However, there was no difference in the quantity of total collagen between the groups (p > 0.54). Conclusions: Aging in rats did not change the quantity of total collagen but reduced the proportion of collagen types I/III and the volume of elastic fibers. |
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| المشرفين على المادة: | 0 (Collagen Type I) 9007-34-5 (Collagen) |
| تواريخ الأحداث: | Date Created: 20210127 Date Completed: 20210129 Latest Revision: 20210130 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC7819684 |
| DOI: | 10.1590/ACB351203 |
| PMID: | 33503216 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-2674 |
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| DOI: | 10.1590/ACB351203 |