دورية أكاديمية
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Computerized Cognitive Training by Healthy Older and Younger Adults: Age Comparisons of Overall Efficacy and Selective Effects on Cognition.

التفاصيل البيبلوغرافية
العنوان: Computerized Cognitive Training by Healthy Older and Younger Adults: Age Comparisons of Overall Efficacy and Selective Effects on Cognition.
المؤلفون: Ng NF; Department of Research and Development, Lumos Labs, San Francisco, CA, United States., Osman AM; Department of Research and Development, Lumos Labs, San Francisco, CA, United States., Kerlan KR; Department of Research and Development, Lumos Labs, San Francisco, CA, United States., Doraiswamy PM; Duke University School of Medicine, Neurocognitive Disorders Program, Department of Psychiatry and Behavioral Sciences, Duke Institute for Brain Sciences, Durham, NC, United States., Schafer RJ; Department of Research and Development, Lumos Labs, San Francisco, CA, United States.
المصدر: Frontiers in neurology [Front Neurol] 2021 Jan 08; Vol. 11, pp. 564317. Date of Electronic Publication: 2021 Jan 08 (Print Publication: 2020).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2295 (Print) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Lausanne : Frontiers Research Foundation, 2010]-
مستخلص: Among the non-pharmacological methods under development for maintaining cognitive function across the lifespan is computerized cognitive training (CCT). There has been considerable interest in using CCT to slow or remediate age-related cognitive decline, both normal and pathological. Toward these ends, it would be useful to know how the effects of CCT on cognitive function vary over the course of normal cognitive aging. Are there changes in either 1) the overall efficacy of CCT or 2) which cognitive faculties are affected? To address these two questions, we reanalyzed results from a large online study by Hardy et al. (1) of 4,715 adults between 18 and 80 that examined effects of CCT on both a neuropsychological test battery and self-reported ratings of cognition and affect in daily living. Combined across all participants, Hardy et al. found greater improvement on both types of assessment following 10 weeks of CCT with the commercial program Lumosity, as compared to practice with a control activity involving computerized crossword puzzles. The present study compared the size of these effects on the older (50-80) and younger (18-49) participants. To address the question of overall efficacy, we examined CCT effects (treatment minus control) on overall performance of the test battery and mean rating. No significant difference on either measure was found between the two age cohorts. To address the question of whether the same magnitude of overall effects on both age cohorts was due to equivalent effects on the same set of underlying cognitive functions, we examined the patterns of CCT effects across individual subtests and rated items. These patterns did not differ significantly between the two age cohorts. Our findings suggest that benefits from CCT can occur to a similar degree and in a similar way across an extended part of the adult lifespan. Moreover, the overall effects of CCT delivered over the internet were of the same small to medium size as those typically found in the lab or clinic. Besides improving access and reducing the cost of CCT for older adults, delivery over the internet makes long-term training more practicable, which could potentially yield larger benefits.
Competing Interests: The current study examined effects of cognitive training with Lumosity on the NeuroCognitive Performance Test, both of which are produced by Lumos Labs, Inc. AO, KK, NN, and RS are current employees and hold stock options in the company. PD is a former unpaid scientific advisor to Lumos and has received research access to Lumosity and the NeuroCognitive Performance Test for an ongoing NIH grant. PD has received grants and advisory or board fees from several other health and technology companies. PD owns stock in several companies whose products are not mentioned here and is a co-inventor on several patents that are not mentioned.
(Copyright © 2021 Ng, Osman, Kerlan, Doraiswamy and Schafer.)
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فهرسة مساهمة: Keywords: Alzheimer's disease; age-related cognitive decline; cognitive aging; computerized cognitive training; digital health; mild cognitive impairment; telemedicine
تواريخ الأحداث: Date Created: 20210128 Latest Revision: 20210130
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7832391
DOI: 10.3389/fneur.2020.564317
PMID: 33505344
قاعدة البيانات: MEDLINE
الوصف
تدمد:1664-2295
DOI:10.3389/fneur.2020.564317