دورية أكاديمية
أعرض في EDS

Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort.

التفاصيل البيبلوغرافية
العنوان: Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort.
المؤلفون: Chan AX; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California., Bakhoum CY; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California., Bangen KJ; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California., Bakhoum MF; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California. Electronic address: mathieu.bakhoum@gmail.com.
المصدر: American journal of ophthalmology [Am J Ophthalmol] 2021 Jun; Vol. 226, pp. 201-205. Date of Electronic Publication: 2021 Jan 30.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : New York, NY : Elsevier Science
Original Publication: [Chicago, etc., Ophthalmic Pub. Co., etc.]
مواضيع طبية MeSH: Dementia/*epidemiology , Retinal Artery Occlusion/*epidemiology , Retinal Vein Occlusion/*epidemiology, Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Dementia/diagnosis ; Female ; Humans ; Male ; Odds Ratio ; Prevalence ; Retinal Artery Occlusion/diagnosis ; Retinal Vein Occlusion/diagnosis ; Retrospective Studies ; Risk Factors
مستخلص: Purpose: To examine the association between cognitive dementia and retinal vascular occlusions.
Design: A retrospective, cross-sectional study.
Methods: Single-institution study population: we reviewed the electronic medical records of 37,208 individuals older than 65 years of age who were evaluated by an ophthalmologist or an optometrist and who also had a medical visit to our institution over a 6-year period. Individuals with and without retinal vascular occlusions were identified by International Classification of Diseases, version 10 (ICD-10) diagnostic codes.
Main Outcome: we analyzed the association between dementia and retinal vascular occlusions after adjusting for covariates which included age, sex, stroke, diabetes mellitus, and hypertension using multiple logistic regression analyses.
Results: Compared to subjects without retinal vascular occlusions, those with retinal vascular occlusions had a higher prevalence of dementia (6.7% vs. 9.3%, respectively; P < .001). After adjusting for either age or stroke, there were no significant associations between retinal vascular occlusions and dementia.
Conclusions: Individuals with retinal vascular occlusions have a higher prevalence of dementia. However, this association is secondary to shared underlying risk factors in this population, such as older age and stroke.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
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معلومات مُعتمدة: I01 CX001842 United States CX CSRD VA; R01 AG063782 United States AG NIA NIH HHS
تواريخ الأحداث: Date Created: 20210202 Date Completed: 20210910 Latest Revision: 20220716
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC9227960
DOI: 10.1016/j.ajo.2021.01.026
PMID: 33529587
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1891
DOI:10.1016/j.ajo.2021.01.026