دورية أكاديمية
Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort.
العنوان: | Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort. |
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المؤلفون: | Chan AX; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California., Bakhoum CY; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California., Bangen KJ; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California., Bakhoum MF; From the Viterbi Family Department of Ophthalmology (AXC, MFB), Shiley Eye Institute, University of California San Diego, La Jolla, California, USA; Division of Pediatric Nephrology (CYB), Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA; Research Service (KJB), Veterans' Affairs San Diego Healthcare System, La Jolla, California, USA; Department of Psychiatry (KJB), University of California San Diego, La Jolla, California. Electronic address: mathieu.bakhoum@gmail.com. |
المصدر: | American journal of ophthalmology [Am J Ophthalmol] 2021 Jun; Vol. 226, pp. 201-205. Date of Electronic Publication: 2021 Jan 30. |
نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 1999- : New York, NY : Elsevier Science Original Publication: [Chicago, etc., Ophthalmic Pub. Co., etc.] |
مواضيع طبية MeSH: | Dementia/*epidemiology , Retinal Artery Occlusion/*epidemiology , Retinal Vein Occlusion/*epidemiology, Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Dementia/diagnosis ; Female ; Humans ; Male ; Odds Ratio ; Prevalence ; Retinal Artery Occlusion/diagnosis ; Retinal Vein Occlusion/diagnosis ; Retrospective Studies ; Risk Factors |
مستخلص: | Purpose: To examine the association between cognitive dementia and retinal vascular occlusions. Design: A retrospective, cross-sectional study. Methods: Single-institution study population: we reviewed the electronic medical records of 37,208 individuals older than 65 years of age who were evaluated by an ophthalmologist or an optometrist and who also had a medical visit to our institution over a 6-year period. Individuals with and without retinal vascular occlusions were identified by International Classification of Diseases, version 10 (ICD-10) diagnostic codes. Main Outcome: we analyzed the association between dementia and retinal vascular occlusions after adjusting for covariates which included age, sex, stroke, diabetes mellitus, and hypertension using multiple logistic regression analyses. Results: Compared to subjects without retinal vascular occlusions, those with retinal vascular occlusions had a higher prevalence of dementia (6.7% vs. 9.3%, respectively; P < .001). After adjusting for either age or stroke, there were no significant associations between retinal vascular occlusions and dementia. Conclusions: Individuals with retinal vascular occlusions have a higher prevalence of dementia. However, this association is secondary to shared underlying risk factors in this population, such as older age and stroke. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
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معلومات مُعتمدة: | I01 CX001842 United States CX CSRD VA; R01 AG063782 United States AG NIA NIH HHS |
تواريخ الأحداث: | Date Created: 20210202 Date Completed: 20210910 Latest Revision: 20220716 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC9227960 |
DOI: | 10.1016/j.ajo.2021.01.026 |
PMID: | 33529587 |
قاعدة البيانات: | MEDLINE |
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