دورية أكاديمية
أعرض في EDS

Nutrition intervention is beneficial to the quality of life of patients with gastrointestinal cancer undergoing chemotherapy in Vietnam.

التفاصيل البيبلوغرافية
العنوان: Nutrition intervention is beneficial to the quality of life of patients with gastrointestinal cancer undergoing chemotherapy in Vietnam.
المؤلفون: Nguyen LT; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.; Department of Nutrition and Dietetic, Hanoi Medical University Hospital, Hanoi, Vietnam., Dang AK; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam., Duong PT; Department of Nutrition and Dietetic, Hanoi Medical University Hospital, Hanoi, Vietnam., Phan HBT; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam., Pham CTT; Department of Nutrition and Dietetic, Hanoi Medical University Hospital, Hanoi, Vietnam., Nguyen ATL; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam., Le HT; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.; Department of Nutrition and Dietetic, Hanoi Medical University Hospital, Hanoi, Vietnam.
المصدر: Cancer medicine [Cancer Med] 2021 Mar; Vol. 10 (5), pp. 1668-1680. Date of Electronic Publication: 2021 Feb 07.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Malden, MA] : John Wiley & Sons Ltd., c2012-
مواضيع طبية MeSH: Health Status* , Quality of Life*, Colonic Neoplasms/*drug therapy , Malnutrition/*diet therapy , Stomach Neoplasms/*drug therapy, Animals ; Cancer Pain/diet therapy ; Colonic Neoplasms/complications ; Colonic Neoplasms/psychology ; Dietary Proteins/administration & dosage ; Energy Intake ; Fatigue/diet therapy ; Female ; Food, Formulated ; Humans ; Male ; Malnutrition/etiology ; Middle Aged ; Milk ; Nutrition Assessment ; Nutritional Status ; Physical Functional Performance ; Sleep Initiation and Maintenance Disorders/diet therapy ; Socioeconomic Factors ; Stomach Neoplasms/complications ; Stomach Neoplasms/psychology ; Treatment Outcome ; Vietnam
مستخلص: Introduction: The best treatment therapy for gastrointestinal cancer patients is assessed by the improvement of health status and quality of life (QoL) after treatments. Malnutrition is related to loss of muscle strengths which leads to lower physical performance and emotional status. Thus, this study aimed to estimate the effects of nutritional interventions on the improvement of QoL among gastrointestinal patients undergoing chemotherapy in Vietnam.
Methods: A quasi-experiment with intervention and control groups for pre- and post-intervention assessment was carried out at the Department of Oncology and Palliative Care-Hanoi Medical University Hospital from 2016 to 2019. Sixty gastrointestinal cancer patients were recruited in each group. The intervention regimen consisted of nutritional counseling, a specific menu with a recommended amount of energy, protein, and formula milk used within 2 months. Nutritional status and QoL of patients were evaluated using The Scored Patient-Generated Subjective Global Assessment (PG-SGA) and The European Organization for Research and Treatment of Cancer (EORTC). The difference in differences (DiD) method was utilized to estimate the outcome between control and intervention groups.
Results: After the intervention, patients of the intervention group had better changes in scores of global health status (Coef =16.68; 95% CI =7.90; 25.46), physical (Coef =14.51; 95% CI =5.34; 23.70), and role functioning (Coef =14.67; 95% CI =1.63; 27.70) compared to the control group. Regarding symptom scales, the level of fatigue, pain, and insomnia symptoms significantly reduced between pre- and post-intervention in the intervention group. In addition, living in urban areas, defined as malnourished and having low prealbumin levels, were positively associated with the lower global health status/QoL score.
Conclusion: Nutritional therapy with high protein was beneficial to the improvement in QoL, physical function and the reduction of negative symptoms among gastrointestinal cancer patients. Early individualized nutritional support in consultation with professional dietitians during chemotherapy plays an integral part in enhancing the QoL and better treatment prognosis.
Clinical Trial Registration Number: NCT04517708.
(© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.)
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فهرسة مساهمة: Keywords: digestive cancer; gastric cancer; nutrition; quality of life
سلسلة جزيئية: ClinicalTrials.gov NCT04517708
المشرفين على المادة: 0 (Dietary Proteins)
تواريخ الأحداث: Date Created: 20210207 Date Completed: 20210716 Latest Revision: 20240331
رمز التحديث: 20240331
مُعرف محوري في PubMed: PMC7940238
DOI: 10.1002/cam4.3766
PMID: 33550719
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-7634
DOI:10.1002/cam4.3766