دورية أكاديمية
Investigation of phytochemical composition and enzyme inhibitory potential of Anagallis arvensis L.
| العنوان: | Investigation of phytochemical composition and enzyme inhibitory potential of Anagallis arvensis L. |
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| المؤلفون: | Saleem H; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor Darul Ehsan, Malaysia.; Institute of Pharmaceutical Sciences (IPS), University of Veterinary & Animal Sciences (UVAS), Lahore, Pakistan., Zengin G; Department of Biology, Faculty of Science, Selcuk University, Campus/Konya, Turkey., Locatelli M; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy., Abidin SAZ; Jeffrey Cheah School of Medicine and Health Sciences, Liquid Chromatography Mass Spectrometery (LCMS) Platform, Monash University, Bandar Sunway, Selangor, Darul Ehsan, Malaysia., Ahemad N; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor Darul Ehsan, Malaysia.; Tropical Medicine and Biology Multidisciplinary Platform, Monash University Malaysia, Bandar Sunway, Selangor Darul Ehsan, Malaysia.; Global Asia in The 21st Century (GA21) Multidisciplinary Research Platform, Monash University, Bandar Sunway, Selangor, Malaysia. |
| المصدر: | Natural product research [Nat Prod Res] 2022 Jul; Vol. 36 (14), pp. 3750-3755. Date of Electronic Publication: 2021 Feb 08. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Anagallis*/chemistry , Monophenol Monooxygenase*, Amylases ; Antioxidants/pharmacology ; Enzyme Inhibitors/chemistry ; Phytochemicals/analysis ; Phytochemicals/pharmacology ; Plant Components, Aerial/chemistry ; Plant Extracts/chemistry |
| مستخلص: | Anagallis arvensis L. commonly known as 'Scarlet Pimpernel' has been used in folklore as natural remedy for treating common ailments. The present research is aimed to explore the phytochemical composition and enzyme inhibition potential of methanol and dichloromethane (DCM) extracts of A. arvensis aerial and root parts. The phytochemical composition was established via HPLC-PDA polyphenolic quantification and UHPLC-MS analysis, while the inhibition potential against amylase and tyrosinase enzymes were assessed using standard in vitro protocols. The HPLC-PDA polyphenolic quantification revealed the presence of important compounds including catechin, gallic acid, chlorogenic acid, and ferulic acid, whereas 34 different secondary metabolites were tentatively identified by UHPLC-MS of both the DCM extracts. All the extracts showed moderate tyrosinase and a weak amylase inhibition activity. The aerial-DCM extract showed comparatively higher tyrosinase and amylase enzyme inhibition potential, which may be due to the presence of secondary metabolites as tentatively identified by its UHPLC-MS profiling. |
| فهرسة مساهمة: | Keywords: Anagallis arvensis; HPLC; amylase; phenolic; secondary metabolites; tyrosinase |
| المشرفين على المادة: | 0 (Antioxidants) 0 (Enzyme Inhibitors) 0 (Phytochemicals) 0 (Plant Extracts) EC 1.14.18.1 (Monophenol Monooxygenase) EC 3.2.1.- (Amylases) |
| تواريخ الأحداث: | Date Created: 20210208 Date Completed: 20220718 Latest Revision: 20220718 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/14786419.2021.1880404 |
| PMID: | 33550873 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2021.1880404 |